Detailed information    

insolico Bioinformatically predicted

Overview

Name   disA   Type   Machinery gene
Locus tag   OIE75_RS21120 Genome accession   NZ_CP109171
Coordinates   4554109..4555233 (-) Length   374 a.a.
NCBI ID   WP_307014187.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_01723     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 4549109..4560233
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OIE75_RS21100 (OIE75_21140) - 4549970..4551679 (+) 1710 WP_329471808.1 histidine kinase -
  OIE75_RS21105 (OIE75_21145) - 4551676..4552350 (+) 675 WP_307014182.1 response regulator transcription factor -
  OIE75_RS21110 (OIE75_21150) - 4552397..4553041 (-) 645 WP_307014183.1 phosphatase PAP2 family protein -
  OIE75_RS21115 (OIE75_21155) - 4553217..4554059 (+) 843 WP_329471809.1 hypothetical protein -
  OIE75_RS21120 (OIE75_21160) disA 4554109..4555233 (-) 1125 WP_307014187.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  OIE75_RS21125 (OIE75_21165) radA 4555315..4556724 (-) 1410 WP_307014189.1 DNA repair protein RadA Machinery gene
  OIE75_RS21130 (OIE75_21170) - 4556900..4558657 (+) 1758 WP_329471810.1 hypothetical protein -
  OIE75_RS21135 (OIE75_21175) - 4558686..4559498 (-) 813 WP_307014192.1 hypothetical protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40057.85 Da        Isoelectric Point: 5.0058

>NTDB_id=671979 OIE75_RS21120 WP_307014187.1 4554109..4555233(-) (disA) [Streptomyces sp. NBC_01723]
MAANDRAAAPGKSGGSAGADGLMRASLSAVAPGTLLRDGLERVLRGNTGGLMVLGSDKTVESMCTGGFVLDVEFTATRLR
ELCKLDGGIVLSSDLSKILRAGVQLLPDPTIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALAELDKLGHAELLELSTVARALGYTGSPETLDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=671979 OIE75_RS21120 WP_307014187.1 4554109..4555233(-) (disA) [Streptomyces sp. NBC_01723]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGAAAGTCCGGTGGGAGTGCCGGTGCCGATGGCCTGATGCGCGCCTCGCT
GAGCGCCGTGGCGCCCGGCACGCTGCTGCGGGACGGCCTGGAACGGGTCCTTCGCGGCAACACCGGCGGTCTGATGGTGC
TGGGTTCGGACAAGACCGTCGAGTCGATGTGTACGGGCGGCTTCGTACTGGACGTCGAGTTCACGGCGACCCGGCTGCGC
GAGCTGTGCAAGCTCGACGGCGGGATCGTGCTCTCCTCGGACCTGTCGAAGATCCTTCGGGCGGGCGTGCAGCTGCTGCC
CGACCCGACCATTCCGACCGAGGAGACCGGTACCCGGCACCGTACGGCGGACCGGGTCAGCAAGCAGGTCGGCTTCCCCG
TCGTGTCCGTTTCGCAGTCCATGCGGCTCATCGCCCTCTACGTCGACGGGCAGCGACGCGTGCTGGAGGACTCCGCGGCG
ATCCTGTCCCGGGCCAACCAGGCGCTCGCCACCCTGGAGCGCTACAAGCTCCGGCTCGACGAGGTCGCCGGCACGCTCTC
CGCGCTGGAGATCGAGGACCTGGTGACCGTCCGGGACGTGTCTGCGGTCGCCCAGCGGCTGGAGATGGTGCGCCGGATCG
CCACCGAGATCGCCGAGTACGTGGTGGAGCTGGGCACGGACGGACGGCTGCTGGCGCTTCAGCTGGACGAGTTGATCGCC
GGCGTGGAGCCGGAGCGCGAGCTGGTCGTACGGGACTACGTGCCCGAGCCGACCGCCAAGCGGTCCCGCACGGTCGACGA
GGCGCTCGCCGAGCTGGACAAGCTCGGCCATGCCGAGCTGCTCGAACTGTCCACGGTGGCCCGGGCGCTGGGCTACACCG
GGTCTCCCGAGACGCTGGACTCGGCGGTGTCGCCGCGCGGGTTCCGGCTGCTGGCGAAGGTGCCGCGGCTGCCGGGCGCG
ATCATCGACCGGCTGGTGGAGCACTTCGGCGGCCTGCAGAAGCTGCTCGCCGCCAGCGTGGACGACCTCCAGACGGTGGA
CGGCGTCGGCGAGGCGCGGGCGCGCAGCGTGCGTGAGGGGCTGTCGCGGCTCGCGGAGTCGTCGATCCTCGAGCGTTACG
TCTGA

Domains

Predicted by InterProScan.

Helix-hairpin-helix motif (HHH_2)

(324-359)

DisA bacterial checkpoint controller nucleotide-binding (DAC)

(38-151)

DisA bacterial checkpoint controller linker region (DisA-linker)

(155-297)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  disA Bacillus subtilis subsp. subtilis str. 168

45.706

96.524

0.441