Detailed information NTG0671810

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: OIE71_RS19510
• Genome accession: NZ_CP109167
• Coordinates: 4400165..4401298 (-)
• Length: 377 a.a.
• NCBI ID: WP_078075735.1
• Uniprot ID: A0A1U9QSN1
• Organism: Streptomyces sp. NBC_01725
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 4395165..4406298

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OIE71_RS19485 (OIE71_19485)	-	4395440..4396306 (-)	867	WP_329034809.1	hypothetical protein	-
OIE71_RS19490 (OIE71_19490)	-	4396294..4396914 (-)	621	WP_147878346.1	SigE family RNA polymerase sigma factor	-
OIE71_RS19495 (OIE71_19495)	-	4397218..4398129 (-)	912	WP_147878345.1	A/G-specific adenine glycosylase	-
OIE71_RS19500 (OIE71_19500)	-	4398283..4399047 (-)	765	WP_329034814.1	phosphatase PAP2 family protein	-
OIE71_RS19505 (OIE71_19505)	-	4399229..4400074 (+)	846	WP_329034816.1	hypothetical protein	-
OIE71_RS19510 (OIE71_19510)	disA	4400165..4401298 (-)	1134	WP_078075735.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
OIE71_RS19515 (OIE71_19515)	radA/sms	4401343..4402755 (-)	1413	WP_147878341.1	DNA repair protein RadA	Machinery gene
OIE71_RS19520 (OIE71_19520)	-	4402861..4404729 (+)	1869	WP_329034818.1	hypothetical protein	-
OIE71_RS19525 (OIE71_19525)	-	4404755..4405573 (-)	819	WP_147878339.1	hypothetical protein	-

Sequence

Protein

• Length: 377 a.a.
• Molecular weight: 40512.47 Da
• Isoelectric Point: 4.9406

>NTDB_id=671810 OIE71_RS19510 WP_078075735.1 4400165..4401298(-) (disA) [Streptomyces sp. NBC_01725]
MAANDRAAAPGKSGGGSGGSGTEALMRASLSAVAPGMALRDGLERILRGNTGGLIVLGMDKTVETMCTGGFVLDVEFTAT
RLRELCKLDGALILDKDITKILRAGVQLVPDASIPTEETGTRHRTADRVSKQCGFPVISVSQSMRLIALYVDGERRVLEE
SAAILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVSQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDE
LIAGVEPERELVVRDYVPEPTAKRSRTVAEAMTELDALSHTELLELPVVARALGYSGSPETLDSAVSPRGYRLLAKVPRL
PGAIIERLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1134 bp

>NTDB_id=671810 OIE71_RS19510 WP_078075735.1 4400165..4401298(-) (disA) [Streptomyces sp. NBC_01725]
GTGGCAGCCAACGACCGGGCAGCAGCACCCGGAAAGTCCGGTGGTGGCTCCGGTGGATCCGGCACCGAAGCGCTGATGCG
CGCCTCACTGAGCGCCGTAGCGCCCGGCATGGCGCTGCGTGACGGGCTGGAGCGGATCCTCCGGGGGAACACCGGCGGTC
TCATCGTCCTGGGCATGGACAAGACCGTCGAGACGATGTGCACGGGCGGCTTCGTGCTGGACGTGGAATTCACCGCCACG
AGGCTCCGCGAGCTCTGCAAGCTCGACGGCGCGCTCATTCTCGACAAAGACATCACCAAAATTCTGCGGGCCGGTGTCCA
GCTCGTGCCCGACGCCTCCATCCCCACCGAGGAGACCGGCACGCGCCACCGCACGGCGGACCGGGTGTCCAAGCAGTGCG
GGTTCCCGGTGATCTCCGTGTCCCAGTCGATGCGGCTGATCGCGCTGTACGTGGACGGGGAGCGCCGGGTCCTGGAGGAG
TCGGCGGCGATCCTGTCGCGCGCCAACCAGGCGCTGGCGACTCTGGAGCGGTACAAGCTCCGGCTGGACGAGGTCGCGGG
CACGCTCTCCGCGCTGGAGATCGAGGACCTGGTGACGGTCCGGGACGTGACGGCGGTGTCGCAGCGCCTGGAGATGGTGC
GCAGGATCGCCACGGAGATCGCCGAGTACGTGGTCGAGTTGGGCACCGACGGGCGGCTTCTCTCCCTCCAGCTCGACGAG
TTGATCGCGGGCGTCGAGCCCGAGCGTGAGCTCGTCGTACGGGACTACGTGCCCGAGCCGACGGCGAAGCGGTCGCGCAC
GGTCGCCGAGGCGATGACCGAGCTGGACGCGCTCTCCCACACGGAGCTGCTGGAACTGCCCGTCGTGGCCCGTGCGTTGG
GCTACAGCGGTTCGCCCGAGACACTGGACTCGGCGGTCTCACCGCGCGGCTACCGGCTGCTGGCCAAGGTGCCGCGTCTG
CCGGGCGCCATCATCGAGCGGCTGGTCGAGCACTTCGGCGGGCTCCAGAAGCTGCTGGCGGCGAGCGTCGACGATCTCCA
GACGGTGGACGGCGTGGGCGAGGCGCGGGCGCGCAGCGTGCGCGAGGGGCTGTCGCGGCTGGCGGAGTCGTCGATCCTGG
AGCGGTACGTCTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller linker region (DisA-linker) (158-300)

• Helix-hairpin-helix motif (HHH_2) (327-362)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (41-154)

3D structure

• AlphaFold DB: A0A1U9QSN1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.938	94.695	0.435