Detailed information NTG0671623

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MUA34_RS04830
• Genome accession: NZ_CP094738
• Coordinates: 1023709..1024752 (+)
• Length: 347 a.a.
• NCBI ID: WP_019166463.1
• Uniprot ID: A0A2A4GVQ0
• Organism: Staphylococcus delphini strain IVB6220
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1018709..1029752

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA34_RS04805 (MUA34_04790)	-	1019554..1020276 (+)	723	WP_262611974.1	type 1 glutamine amidotransferase	-
MUA34_RS04810 (MUA34_04795)	-	1020655..1021653 (-)	999	WP_262611975.1	aromatic acid exporter family protein	-
MUA34_RS04815 (MUA34_04800)	map	1021750..1022511 (+)	762	WP_019166460.1	type I methionyl aminopeptidase	-
MUA34_RS04820 (MUA34_04805)	-	1022609..1022998 (+)	390	WP_262611976.1	hypothetical protein	-
MUA34_RS04825 (MUA34_04810)	liaF	1023011..1023712 (+)	702	WP_096597675.1	cell wall-active antibiotics response protein LiaF	-
MUA34_RS04830 (MUA34_04815)	vraS	1023709..1024752 (+)	1044	WP_019166463.1	sensor histidine kinase	Regulator
MUA34_RS04835 (MUA34_04820)	vraR	1024742..1025371 (+)	630	WP_262611977.1	response regulator transcription factor	Regulator
MUA34_RS04840 (MUA34_04825)	-	1026006..1026587 (-)	582	WP_262611978.1	carbonic anhydrase	-
MUA34_RS04845 (MUA34_04830)	-	1026620..1027966 (-)	1347	WP_262611979.1	YihY/virulence factor BrkB family protein	-
MUA34_RS04850 (MUA34_04835)	-	1028182..1028469 (-)	288	WP_014613485.1	YtxH domain-containing protein	-
MUA34_RS04855 (MUA34_04840)	-	1028477..1028935 (-)	459	WP_262611980.1	low molecular weight protein-tyrosine-phosphatase	-
MUA34_RS04860 (MUA34_04845)	-	1029069..1029272 (+)	204	WP_019169369.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39911.18 Da
• Isoelectric Point: 5.0397

>NTDB_id=671623 MUA34_RS04830 WP_019166463.1 1023709..1024752(+) (vraS) [Staphylococcus delphini strain IVB6220]
MNHYVRAIGSMLILVYSMLTAFFFIDKVFTNIIFFQGMFYTQILGIPVFIFLNLVVIFLCIIVGSVLAYKINQQNDWVKQ
QIVRAFEGETVGINDQQLELYNETIELYQALVPLNQELHKMRIKTQNLTNETYNLNDLKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETDLAPPLDQQIPTLEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKSLVTDLQRKVPIKVVQEI
DEFEVPKGIEDHLFRITQEAISNTLRHAEGTQVTVELLNRNDYLLLRIQDDGIGFNVDDKLEQSYGLKNMRERAIEIGAT
FHIVSLPDAGTRIEVKAPLEKEEQHDN

Nucleotide

• Length: 1044 bp

>NTDB_id=671623 MUA34_RS04830 WP_019166463.1 1023709..1024752(+) (vraS) [Staphylococcus delphini strain IVB6220]
ATGAATCACTACGTCCGAGCGATAGGTTCGATGCTCATTCTCGTATATAGTATGCTCACCGCGTTTTTCTTTATCGATAA
AGTGTTTACCAATATTATTTTCTTTCAAGGCATGTTTTATACACAAATTTTAGGGATTCCTGTTTTTATCTTTTTAAATT
TAGTCGTCATTTTTTTATGTATTATCGTGGGCAGTGTGTTAGCTTATAAAATCAATCAACAAAATGATTGGGTGAAGCAA
CAAATCGTTCGTGCTTTCGAAGGCGAAACAGTGGGAATCAATGATCAACAACTTGAGCTGTATAATGAAACGATTGAATT
GTACCAAGCGCTCGTCCCATTGAATCAAGAACTGCATAAAATGCGGATTAAAACACAAAATTTAACGAATGAAACGTATA
ATTTAAATGATTTGAAGGTGAAAAAGATTATAGAAGATGAACGGCAGCGTTTAGCACGAGAATTGCATGATAGTGTGTCG
CAACAACTTTTCGCGGCAAGTATGATGTTGTCTGCAATCAAGGAAACAGATTTAGCTCCACCGTTAGACCAACAAATTCC
AACGTTAGAAAAAATGGTGCAAGACTCACAACTTGAAATGCGTGCACTGTTACTTCATTTAAGACCTATAGGATTGAAGG
ATAAATCGTTAGGTGAGGGGATAAAATCGCTCGTGACGGATTTACAACGCAAAGTGCCCATTAAAGTCGTGCAAGAAATT
GATGAGTTTGAAGTCCCTAAAGGTATTGAGGATCACCTTTTTAGGATTACCCAAGAAGCGATTTCCAATACGTTACGACA
TGCTGAGGGAACGCAAGTAACAGTAGAATTACTTAACCGCAATGATTATTTATTGTTGCGTATACAAGATGACGGCATTG
GATTTAATGTCGATGATAAATTAGAACAAAGTTATGGATTAAAAAATATGCGTGAACGTGCAATAGAGATTGGTGCCACG
TTTCATATCGTCTCATTACCTGATGCAGGGACGAGAATAGAAGTGAAAGCACCACTTGAAAAGGAGGAACAGCATGACAA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-341)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A2A4GVQ0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	83.573	100	0.836