Detailed information
Bioinformatically predicted
Overview
| Name | ccrA | Type | Machinery gene |
| Locus tag | MUA70_RS00170 | Genome accession | NZ_CP094731 |
| Coordinates | 37795..39156 (-) | Length | 453 a.a. |
| NCBI ID | WP_061544228.1 | Uniprot ID | - |
| Organism | Staphylococcus epidermidis strain IVB6208 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| SCCmec | 36469..60183 | 37795..39156 | within | 0 |
Gene organization within MGE regions
Location: 36469..60183
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MUA70_RS00170 (MUA70_00170) | ccrA | 37795..39156 (-) | 1362 | WP_061544228.1 | cassette chromosome recombinase CcrA | Machinery gene |
| MUA70_RS00175 (MUA70_00175) | cch1 | 39367..41133 (-) | 1767 | WP_061544227.1 | cassette chromosome replicative helicase | - |
| MUA70_RS00180 (MUA70_00180) | ssb | 41133..41426 (-) | 294 | WP_046464617.1 | cassette chromosome ssDNA-binding protein | - |
| MUA70_RS00185 (MUA70_00185) | - | 41597..43111 (-) | 1515 | WP_108703122.1 | hypothetical protein | - |
| MUA70_RS00190 (MUA70_00190) | - | 43742..44653 (+) | 912 | WP_046464619.1 | ABC transporter substrate-binding protein | - |
| MUA70_RS00195 (MUA70_00195) | - | 44903..45564 (-) | 662 | Protein_36 | IS6 family transposase | - |
| MUA70_RS00200 (MUA70_00200) | - | 45678..46634 (+) | 957 | WP_000282655.1 | thymidylate synthase | - |
| MUA70_RS00205 (MUA70_00205) | - | 46676..47161 (+) | 486 | WP_000175735.1 | trimethoprim-resistant dihydrofolate reductase DfrS1 | - |
| MUA70_RS00210 (MUA70_00210) | - | 47171..47569 (+) | 399 | Protein_39 | DegV family protein | - |
| MUA70_RS00215 (MUA70_00215) | - | 47625..48299 (-) | 675 | WP_001106019.1 | IS6-like element IS257 family transposase | - |
| MUA70_RS00220 (MUA70_00220) | - | 48335..48724 (+) | 390 | WP_020444595.1 | hydroxymethylglutaryl-CoA synthase | - |
| MUA70_RS00225 (MUA70_00225) | - | 49601..50344 (+) | 744 | WP_000958858.1 | glycerophosphoryl diester phosphodiesterase | - |
| MUA70_RS00230 (MUA70_00230) | - | 50441..50869 (+) | 429 | WP_000872606.1 | MaoC family dehydratase | - |
| MUA70_RS00235 (MUA70_00235) | mecA | 50915..52924 (-) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| MUA70_RS00240 (MUA70_00240) | - | 53021..54007 (+) | 987 | WP_001549960.1 | beta-lactam sensor/signal transducer MecR1 | - |
| MUA70_RS00245 (MUA70_00245) | - | 53994..54239 (+) | 246 | Protein_46 | type I restriction enzyme endonuclease domain-containing protein | - |
| MUA70_RS00250 (MUA70_00250) | - | 54230..55840 (-) | 1611 | Protein_47 | IS1182 family transposase | - |
| MUA70_RS00255 (MUA70_00255) | - | 55889..56395 (-) | 507 | WP_001092195.1 | DUF1643 domain-containing protein | - |
| MUA70_RS00260 (MUA70_00260) | - | 56410..56721 (-) | 312 | WP_001024803.1 | DUF960 family protein | - |
| MUA70_RS00265 (MUA70_00265) | - | 56808..57158 (-) | 351 | WP_070508371.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| MUA70_RS00270 (MUA70_00270) | - | 57841..58431 (-) | 591 | WP_070508372.1 | hypothetical protein | - |
| MUA70_RS00275 (MUA70_00275) | ccrB | 58558..60183 (-) | 1626 | WP_262622810.1 | cassette chromosome recombinase CcrB | Machinery gene |
Sequence
Protein
Download Length: 453 a.a. Molecular weight: 52936.78 Da Isoelectric Point: 9.8297
>NTDB_id=671483 MUA70_RS00170 WP_061544228.1 37795..39156(-) (ccrA) [Staphylococcus epidermidis strain IVB6208]
MEKAIAYVRQSTLKQQSLATQKSLIIDTAKQHGWSNVTFYDDKKTGGHTKRSGYQKMVEVITSGECKVLCCYRLNRLHRN
FKNAIQFFEICKKHHVTIISVNDGYFDLSKEFDCFRLNILMSLAEMESNNISEQTRNGIREKAKQGKLITTHAPFGYHYS
KGHFIVNAEEAPTIKAVYRWYLQGLGYKKISQKLDKDMNFISRKPYQVRNILLNPNYCGRVINKYGTFNDIVPPIINVDT
FEEAQERRIHKQHNRSNSRNKLKRRIKCPYCQSTLTNLTIKKEHRSLRYYVCPKNMNEAYHTCPFKGINAQMIETEVLNT
CKVYCGNQSFHDKLNETILKALKHQQMKHRQSHLTQEQLIEKLAQNQIDIETFKRLSAGFEREERYSNYSSNQIAETIRH
VVKDKLTLEIIAPLIDDITITQTKQLQGIYFKNSPLNIVEQSHLITPERNEVI
MEKAIAYVRQSTLKQQSLATQKSLIIDTAKQHGWSNVTFYDDKKTGGHTKRSGYQKMVEVITSGECKVLCCYRLNRLHRN
FKNAIQFFEICKKHHVTIISVNDGYFDLSKEFDCFRLNILMSLAEMESNNISEQTRNGIREKAKQGKLITTHAPFGYHYS
KGHFIVNAEEAPTIKAVYRWYLQGLGYKKISQKLDKDMNFISRKPYQVRNILLNPNYCGRVINKYGTFNDIVPPIINVDT
FEEAQERRIHKQHNRSNSRNKLKRRIKCPYCQSTLTNLTIKKEHRSLRYYVCPKNMNEAYHTCPFKGINAQMIETEVLNT
CKVYCGNQSFHDKLNETILKALKHQQMKHRQSHLTQEQLIEKLAQNQIDIETFKRLSAGFEREERYSNYSSNQIAETIRH
VVKDKLTLEIIAPLIDDITITQTKQLQGIYFKNSPLNIVEQSHLITPERNEVI
Nucleotide
Download Length: 1362 bp
>NTDB_id=671483 MUA70_RS00170 WP_061544228.1 37795..39156(-) (ccrA) [Staphylococcus epidermidis strain IVB6208]
ATGGAAAAAGCCATTGCTTATGTACGTCAAAGTACACTCAAACAACAAAGCTTAGCGACTCAGAAATCCCTCATTATAGA
CACTGCTAAGCAACATGGATGGTCCAATGTAACATTTTATGATGATAAAAAAACAGGTGGACATACAAAGCGTTCAGGCT
ATCAAAAAATGGTAGAAGTGATTACATCTGGAGAGTGTAAAGTATTATGTTGCTATCGGCTAAATCGGCTCCATCGTAAT
TTCAAAAATGCTATACAATTCTTTGAAATTTGTAAAAAGCATCACGTCACAATCATCAGTGTTAACGATGGATATTTTGA
TTTGTCTAAAGAGTTTGATTGCTTTCGCTTAAACATACTCATGAGTCTAGCAGAAATGGAATCGAACAACATCAGCGAAC
AAACACGAAATGGGATAAGAGAAAAAGCCAAACAAGGTAAGTTGATTACAACACACGCCCCTTTTGGTTATCACTACAGC
AAAGGTCACTTTATTGTAAATGCAGAAGAAGCACCGACAATCAAAGCCGTTTATCGTTGGTATTTACAAGGACTTGGTTA
CAAGAAAATTTCTCAAAAGCTGGATAAAGATATGAATTTTATTTCTCGTAAGCCCTATCAAGTTAGAAATATTCTCTTGA
ACCCTAACTATTGTGGTCGTGTCATTAATAAATATGGAACGTTTAATGATATCGTTCCACCTATTATTAATGTTGATACG
TTTGAGGAAGCACAAGAGCGTCGTATTCATAAACAACACAATCGATCCAATTCTAGAAATAAGTTAAAGCGACGAATCAA
ATGTCCTTACTGTCAATCAACATTAACAAACTTAACGATAAAAAAAGAACATCGTTCTCTACGTTACTATGTCTGTCCTA
AAAATATGAATGAAGCCTATCATACGTGTCCATTTAAAGGCATCAATGCGCAAATGATTGAAACAGAGGTCCTAAACACT
TGTAAAGTATACTGTGGCAATCAATCATTTCATGACAAATTAAATGAGACAATACTAAAAGCTCTAAAACACCAACAAAT
GAAACACAGACAATCACATCTAACACAAGAACAACTCATCGAAAAACTAGCACAAAATCAAATTGATATAGAAACATTTA
AACGGTTATCTGCTGGCTTTGAAAGAGAAGAACGTTACTCTAATTATTCATCCAATCAAATTGCTGAAACAATCCGTCAT
GTAGTCAAAGATAAATTGACATTAGAAATCATAGCACCTTTGATTGATGACATTACAATAACTCAAACTAAACAATTACA
AGGAATCTACTTTAAAAACAGTCCACTCAATATCGTTGAACAATCGCATTTAATAACTCCTGAAAGGAATGAAGTCATAT
GA
ATGGAAAAAGCCATTGCTTATGTACGTCAAAGTACACTCAAACAACAAAGCTTAGCGACTCAGAAATCCCTCATTATAGA
CACTGCTAAGCAACATGGATGGTCCAATGTAACATTTTATGATGATAAAAAAACAGGTGGACATACAAAGCGTTCAGGCT
ATCAAAAAATGGTAGAAGTGATTACATCTGGAGAGTGTAAAGTATTATGTTGCTATCGGCTAAATCGGCTCCATCGTAAT
TTCAAAAATGCTATACAATTCTTTGAAATTTGTAAAAAGCATCACGTCACAATCATCAGTGTTAACGATGGATATTTTGA
TTTGTCTAAAGAGTTTGATTGCTTTCGCTTAAACATACTCATGAGTCTAGCAGAAATGGAATCGAACAACATCAGCGAAC
AAACACGAAATGGGATAAGAGAAAAAGCCAAACAAGGTAAGTTGATTACAACACACGCCCCTTTTGGTTATCACTACAGC
AAAGGTCACTTTATTGTAAATGCAGAAGAAGCACCGACAATCAAAGCCGTTTATCGTTGGTATTTACAAGGACTTGGTTA
CAAGAAAATTTCTCAAAAGCTGGATAAAGATATGAATTTTATTTCTCGTAAGCCCTATCAAGTTAGAAATATTCTCTTGA
ACCCTAACTATTGTGGTCGTGTCATTAATAAATATGGAACGTTTAATGATATCGTTCCACCTATTATTAATGTTGATACG
TTTGAGGAAGCACAAGAGCGTCGTATTCATAAACAACACAATCGATCCAATTCTAGAAATAAGTTAAAGCGACGAATCAA
ATGTCCTTACTGTCAATCAACATTAACAAACTTAACGATAAAAAAAGAACATCGTTCTCTACGTTACTATGTCTGTCCTA
AAAATATGAATGAAGCCTATCATACGTGTCCATTTAAAGGCATCAATGCGCAAATGATTGAAACAGAGGTCCTAAACACT
TGTAAAGTATACTGTGGCAATCAATCATTTCATGACAAATTAAATGAGACAATACTAAAAGCTCTAAAACACCAACAAAT
GAAACACAGACAATCACATCTAACACAAGAACAACTCATCGAAAAACTAGCACAAAATCAAATTGATATAGAAACATTTA
AACGGTTATCTGCTGGCTTTGAAAGAGAAGAACGTTACTCTAATTATTCATCCAATCAAATTGCTGAAACAATCCGTCAT
GTAGTCAAAGATAAATTGACATTAGAAATCATAGCACCTTTGATTGATGACATTACAATAACTCAAACTAAACAATTACA
AGGAATCTACTTTAAAAACAGTCCACTCAATATCGTTGAACAATCGCATTTAATAACTCCTGAAAGGAATGAAGTCATAT
GA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrA | Staphylococcus aureus COL |
55.305 |
97.792 |
0.541 |
| ccrA | Staphylococcus aureus N315 |
52.37 |
97.792 |
0.512 |