Detailed information NTG0671456

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MUA58_RS04475
• Genome accession: NZ_CP094729
• Coordinates: 966882..967928 (+)
• Length: 348 a.a.
• NCBI ID: WP_002447441.1
• Uniprot ID: -
• Organism: Staphylococcus epidermidis strain IVB6210
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 961882..972928

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA58_RS04450 (MUA58_04445)	-	963022..963558 (+)	537	WP_002447446.1	hypothetical protein	-
MUA58_RS04455 (MUA58_04450)	-	963710..964696 (-)	987	WP_002447445.1	aromatic acid exporter family protein	-
MUA58_RS04460 (MUA58_04455)	map	964870..965625 (+)	756	WP_002447444.1	type I methionyl aminopeptidase	-
MUA58_RS04465 (MUA58_04460)	-	965783..966169 (+)	387	WP_002458548.1	hypothetical protein	-
MUA58_RS04470 (MUA58_04465)	liaF	966184..966885 (+)	702	WP_002447442.1	cell wall-active antibiotics response protein LiaF	-
MUA58_RS04475 (MUA58_04470)	vraS	966882..967928 (+)	1047	WP_002447441.1	sensor histidine kinase	Regulator
MUA58_RS04480 (MUA58_04475)	vraR	967918..968547 (+)	630	WP_002473914.1	two-component system response regulator VraR	Regulator
MUA58_RS04485 (MUA58_04480)	-	968604..969782 (-)	1179	WP_262615096.1	YihY/virulence factor BrkB family protein	-
MUA58_RS04490 (MUA58_04485)	-	970188..970472 (-)	285	WP_002447438.1	YtxH domain-containing protein	-
MUA58_RS04495 (MUA58_04490)	-	970480..970944 (-)	465	WP_002458546.1	low molecular weight protein-tyrosine-phosphatase	-
MUA58_RS04500 (MUA58_04495)	-	971086..971301 (+)	216	WP_001830421.1	DUF1128 domain-containing protein	-
MUA58_RS04505 (MUA58_04500)	-	971303..972544 (+)	1242	WP_262615097.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40114.53 Da
• Isoelectric Point: 5.8512

>NTDB_id=671456 MUA58_RS04475 WP_002447441.1 966882..967928(+) (vraS) [Staphylococcus epidermidis strain IVB6210]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVFLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVLHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=671456 MUA58_RS04475 WP_002447441.1 966882..967928(+) (vraS) [Staphylococcus epidermidis strain IVB6210]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAAGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTTTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCC
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACTATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAGAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCAAGGGAATTGCATGATTCTGTTAGC
CAACAATTATTTGCTGCGAGCATGATGCTATCGGCAATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTGTTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTCTAGGTGAAGGTATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTTTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGTATTGAAGATCATTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACGAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GATTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTAAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	92.442	98.851	0.914