Detailed information NTG0671388

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MUA29_RS04640
• Genome accession: NZ_CP094726
• Coordinates: 991351..992397 (+)
• Length: 348 a.a.
• NCBI ID: WP_002494127.1
• Uniprot ID: -
• Organism: Staphylococcus epidermidis strain IVB6256
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 986351..997397

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA29_RS04620 (MUA29_04605)	-	988179..989165 (-)	987	WP_262608851.1	aromatic acid exporter family protein	-
MUA29_RS04625 (MUA29_04610)	map	989339..990094 (+)	756	WP_002447444.1	type I methionyl aminopeptidase	-
MUA29_RS04630 (MUA29_04615)	-	990252..990638 (+)	387	WP_001830382.1	hypothetical protein	-
MUA29_RS04635 (MUA29_04620)	liaF	990653..991354 (+)	702	WP_002473931.1	cell wall-active antibiotics response protein LiaF	-
MUA29_RS04640 (MUA29_04625)	vraS	991351..992397 (+)	1047	WP_002494127.1	sensor histidine kinase	Regulator
MUA29_RS04645 (MUA29_04630)	vraR	992387..993016 (+)	630	WP_002473914.1	two-component system response regulator VraR	Regulator
MUA29_RS04650 (MUA29_04635)	-	993073..994251 (-)	1179	WP_262608853.1	YihY/virulence factor BrkB family protein	-
MUA29_RS04655 (MUA29_04640)	-	994658..994942 (-)	285	WP_002473916.1	YtxH domain-containing protein	-
MUA29_RS04660 (MUA29_04645)	-	994950..995414 (-)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
MUA29_RS04665 (MUA29_04650)	-	995555..995770 (+)	216	WP_001830421.1	DUF1128 domain-containing protein	-
MUA29_RS04670 (MUA29_04655)	-	995772..997013 (+)	1242	WP_002498658.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 39994.42 Da
• Isoelectric Point: 6.0544

>NTDB_id=671388 MUA29_RS04640 WP_002494127.1 991351..992397(+) (vraS) [Staphylococcus epidermidis strain IVB6256]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVLLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQGDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=671388 MUA29_RS04640 WP_002494127.1 991351..992397(+) (vraS) [Staphylococcus epidermidis strain IVB6256]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAGGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTCTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCA
CAAATAGAAAGATCAATAGAAGGACAAACGGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAAAATTTAACTAATGAAAACTACA
ACATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCCAGGGAATTACATGATTCTGTTAGT
CAACAATTATTTGCTGCGAGCATGATGCTATCAGCGATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTGTTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTTTAGGTGAAGGAATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTGTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGCATTGAAGATCATTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACAAAAGTAACTGTGGAATTATTTAATCAAGGGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GGTTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	93.023	98.851	0.92