Detailed information NTG0671058

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MUA61_RS04480
• Genome accession: NZ_CP094715
• Coordinates: 929203..930246 (+)
• Length: 347 a.a.
• NCBI ID: WP_017637854.1
• Uniprot ID: A0A654BBJ5
• Organism: Staphylococcus pasteuri strain IVB6198
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 924203..935246

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA61_RS04455 (MUA61_04455)	-	924935..925660 (+)	726	WP_046467432.1	type 1 glutamine amidotransferase	-
MUA61_RS04460 (MUA61_04460)	-	926046..927032 (-)	987	WP_029056008.1	aromatic acid exporter family protein	-
MUA61_RS04465 (MUA61_04465)	map	927198..927953 (+)	756	WP_017637857.1	type I methionyl aminopeptidase	-
MUA61_RS04470 (MUA61_04470)	-	928104..928490 (+)	387	WP_017637856.1	DUF2543 family protein	-
MUA61_RS04475 (MUA61_04475)	liaF	928505..929206 (+)	702	WP_017637855.1	cell wall-active antibiotics response protein LiaF	-
MUA61_RS04480 (MUA61_04480)	vraS	929203..930246 (+)	1044	WP_017637854.1	sensor histidine kinase	Regulator
MUA61_RS04485 (MUA61_04485)	vraR	930236..930865 (+)	630	WP_017637853.1	two-component system response regulator VraR	Regulator
MUA61_RS04490 (MUA61_04490)	-	930956..932194 (-)	1239	WP_070452157.1	YihY/virulence factor BrkB family protein	-
MUA61_RS04495 (MUA61_04495)	-	932484..932768 (-)	285	WP_017637851.1	hypothetical protein	-
MUA61_RS04500 (MUA61_04500)	-	932773..933237 (-)	465	WP_017637850.1	low molecular weight protein-tyrosine-phosphatase	-
MUA61_RS04505 (MUA61_04505)	-	933399..933581 (+)	183	WP_037555624.1	DUF1128 domain-containing protein	-
MUA61_RS04510 (MUA61_04510)	-	933595..934836 (+)	1242	WP_070452162.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40047.46 Da
• Isoelectric Point: 6.2449

>NTDB_id=671058 MUA61_RS04480 WP_017637854.1 929203..930246(+) (vraS) [Staphylococcus pasteuri strain IVB6198]
MNHYIRAIGSMLILTYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNIIVILLCIIVGSVLAYKINQQNDWINS
QIERSIEGETVGINDQNIELYSETLEIYHTLVPLNQELHRLRMKTQNLTNENYNMNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPVLEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QEFKVPKGIEDHLFRITQEAISNTLRHSNGTRVTVELFNKQDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYGD

Nucleotide

• Length: 1044 bp

>NTDB_id=671058 MUA61_RS04480 WP_017637854.1 929203..930246(+) (vraS) [Staphylococcus pasteuri strain IVB6198]
ATGAATCACTATATAAGAGCAATAGGCTCTATGCTCATTTTAACGTATAGTATGTTAACCGCATTTTTATTTATTGATAA
AGTATTTGTTAACATCATCTATTTTCAAGGTATGTTCTATACACAGATTTTTGGCATACCTGTATTCTTATTTTTAAATA
TCATAGTGATATTATTATGTATCATTGTAGGCTCTGTTTTAGCTTATAAAATTAATCAACAGAATGACTGGATTAATTCT
CAAATAGAACGATCTATTGAAGGTGAAACAGTTGGTATCAATGACCAAAATATAGAATTATATAGTGAAACACTGGAAAT
ATATCATACACTTGTACCATTAAATCAGGAATTACATCGATTAAGAATGAAAACACAAAACTTAACTAATGAAAACTACA
ACATGAACGATGTAAAAGTTAAAAAGATTATTGAAGACGAAAGACAACGTCTAGCTAGAGAATTACATGACTCAGTAAGT
CAACAATTATTCGCTGCGAGTATGATGTTATCAGCGATTAAAGAAACTAAATTAGAACCCCCATTAGACCAACAAATTCC
AGTTTTAGAGAAAATGGTACAAGATTCACAACTTGAAATGAGAGCTTTATTATTACATTTACGACCTCTAGGGTTGAAAG
ATAAGTCCTTAGGTGAAGGAATTAAAGATTTAGTTATAGATCTTCAAAAGAAAGTTCCGATGAAAGTTGTACATGAAATA
CAAGAATTTAAAGTTCCTAAAGGTATCGAAGATCATTTATTTAGAATTACTCAAGAAGCTATTTCAAATACATTAAGACA
TTCTAATGGCACTAGAGTGACGGTTGAACTATTTAATAAGCAAGATTATTTATTATTACGTATACAAGATAATGGTAAAG
GCTTTAATGTAGATGAAAAATTGGAACAAAGCTATGGTTTAAAAAATATGAGAGAACGTGCATTAGAAATTGGTGCTACA
TTCCATATCGTTTCGTTACCTGATTCCGGAACACGTATAGAAGTTAAAGCCCCATTGAACAAGGAGGATTCTTATGGCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

3D structure

• AlphaFold DB: A0A654BBJ5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	94.524	100	0.945