Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   MUA72_RS04335 Genome accession   NZ_CP094714
Coordinates   956930..957559 (+) Length   209 a.a.
NCBI ID   WP_016425506.1    Uniprot ID   S2XKD5
Organism   Staphylococcus schleiferi strain IVB6176     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 951930..962559
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUA72_RS04310 (MUA72_04300) - 952842..953840 (-) 999 WP_194368683.1 aromatic acid exporter family protein -
  MUA72_RS04315 (MUA72_04305) map 953938..954699 (+) 762 WP_167732697.1 type I methionyl aminopeptidase -
  MUA72_RS04320 (MUA72_04310) - 954797..955186 (+) 390 WP_016425509.1 hypothetical protein -
  MUA72_RS04325 (MUA72_04315) liaF 955199..955900 (+) 702 WP_016425508.1 cell wall-active antibiotics response protein LiaF -
  MUA72_RS04330 (MUA72_04320) vraS 955897..956940 (+) 1044 WP_050330549.1 sensor histidine kinase Regulator
  MUA72_RS04335 (MUA72_04325) vraR 956930..957559 (+) 630 WP_016425506.1 response regulator transcription factor Regulator
  MUA72_RS04340 (MUA72_04330) - 957614..958186 (-) 573 WP_016425505.1 carbonic anhydrase -
  MUA72_RS04345 (MUA72_04335) - 958219..959478 (-) 1260 WP_016425504.1 YihY/virulence factor BrkB family protein -
  MUA72_RS04350 (MUA72_04340) - 959769..960056 (-) 288 WP_016425503.1 YtxH domain-containing protein -
  MUA72_RS04355 (MUA72_04345) - 960064..960522 (-) 459 WP_016425502.1 low molecular weight protein-tyrosine-phosphatase -
  MUA72_RS04360 (MUA72_04350) - 960655..960858 (+) 204 WP_016425501.1 DUF1128 family protein -
  MUA72_RS04365 (MUA72_04355) - 960877..962109 (+) 1233 WP_016425500.1 aminopeptidase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23479.04 Da        Isoelectric Point: 5.0018

>NTDB_id=671024 MUA72_RS04335 WP_016425506.1 956930..957559(+) (vraR) [Staphylococcus schleiferi strain IVB6176]
MTIKVLFVDDHEMVRIGISSYLSTQPDIEVVGEGASGKEAIQKAHELHPDLILMDLVMTDMDGVEATTQIKKDLPHIKVV
MLTSYIEDKEVYRALDAGVDSYILKTTSASDIAEAIRKTSQGESVFEAEVLVKMRNRMKQRAELYELLTEREMEILLLIS
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHGLIE

Nucleotide


Download         Length: 630 bp        

>NTDB_id=671024 MUA72_RS04335 WP_016425506.1 956930..957559(+) (vraR) [Staphylococcus schleiferi strain IVB6176]
ATGACAATTAAAGTATTATTTGTAGATGATCATGAAATGGTTAGAATTGGAATATCTAGCTATTTATCCACGCAACCGGA
TATTGAGGTTGTAGGGGAAGGGGCTTCAGGGAAAGAGGCTATTCAAAAAGCACATGAACTTCATCCGGATTTAATTTTAA
TGGACTTAGTGATGACAGACATGGACGGTGTTGAAGCGACAACACAAATCAAAAAAGACTTACCACATATTAAAGTGGTC
ATGCTTACAAGTTATATTGAGGATAAAGAAGTTTATCGTGCCTTAGATGCAGGTGTCGATAGTTATATTCTTAAAACGAC
AAGTGCAAGTGATATTGCTGAAGCGATACGAAAAACAAGTCAAGGCGAGTCTGTATTTGAAGCAGAAGTCCTTGTGAAAA
TGCGCAATCGCATGAAACAAAGAGCGGAATTATATGAGTTACTGACAGAGCGTGAAATGGAAATCCTATTATTGATATCA
AAAGGGTATTCAAATCAAGAAATCGCAAGTGCTTCACATATTACGATTAAAACAGTGAAAACACATGTGAGTAATATTTT
AAGTAAATTAGAAGTGCAAGATCGTACGCAAGCAGTGATTTATGCCTTTCAACATGGATTAATTGAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB S2XKD5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

91.388

100

0.914
  degU Bacillus subtilis subsp. subtilis str. 168

35.714

100

0.383