Detailed information NTG0670992

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MUA91_RS04310
• Genome accession: NZ_CP094713
• Coordinates: 952625..953668 (+)
• Length: 347 a.a.
• NCBI ID: WP_050330549.1
• Uniprot ID: A0A0K1ACB9
• Organism: Staphylococcus schleiferi strain IVB6180
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 947625..958668

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA91_RS04285 (MUA91_04275)	-	948047..949186 (+)	1140	WP_242678349.1	exo-alpha-sialidase	-
MUA91_RS04290 (MUA91_04280)	-	949570..950568 (-)	999	WP_194368683.1	FUSC family protein	-
MUA91_RS04295 (MUA91_04285)	map	950666..951427 (+)	762	WP_167732697.1	type I methionyl aminopeptidase	-
MUA91_RS04300 (MUA91_04290)	-	951525..951914 (+)	390	WP_016425509.1	hypothetical protein	-
MUA91_RS04305 (MUA91_04295)	liaF	951927..952628 (+)	702	WP_016425508.1	cell wall-active antibiotics response protein LiaF	-
MUA91_RS04310 (MUA91_04300)	vraS	952625..953668 (+)	1044	WP_050330549.1	sensor histidine kinase	Regulator
MUA91_RS04315 (MUA91_04305)	vraR	953658..954287 (+)	630	WP_016425506.1	response regulator transcription factor	Regulator
MUA91_RS04320 (MUA91_04310)	-	954342..954914 (-)	573	WP_016425505.1	beta-class carbonic anhydrase	-
MUA91_RS04325 (MUA91_04315)	-	954947..956206 (-)	1260	WP_016425504.1	YihY/virulence factor BrkB family protein	-
MUA91_RS04330 (MUA91_04320)	-	956497..956784 (-)	288	WP_016425503.1	YtxH domain-containing protein	-
MUA91_RS04335 (MUA91_04325)	-	956792..957250 (-)	459	WP_016425502.1	low molecular weight protein-tyrosine-phosphatase	-
MUA91_RS04340 (MUA91_04330)	-	957383..957586 (+)	204	WP_016425501.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40139.47 Da
• Isoelectric Point: 5.4523

>NTDB_id=670992 MUA91_RS04310 WP_050330549.1 952625..953668(+) (vraS) [Staphylococcus schleiferi strain IVB6180]
MNHYVRAIGSMLILVYSMFTAFFFIDKVFTNIIYFQGMFYTQIFGIPVFIFLNLIVIFLCIIVGSVLAYKINQQNDWLKQ
QIERAFEGETVGINDQHIELYNETIELYQALVPLNQELHKMRIKTQNLTNESYNMNDLKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETELTPPLDQQIPTLEKMVQDSQLEMRALLLHLRPIGLKDRSLGEGIKSLVTDLQRKVPMKVVQEI
DEFEVPKGIEDHLFRITQEAISNTLRHAKGKQVTVELLNREDYLLLRIQDDGIGFNVDDKLEQSYGLKNMRERAIEIGAT
FHIVSLPDAGTRIEVKAPLDKEVHNDN

Nucleotide

• Length: 1044 bp

>NTDB_id=670992 MUA91_RS04310 WP_050330549.1 952625..953668(+) (vraS) [Staphylococcus schleiferi strain IVB6180]
ATGAACCATTACGTTCGTGCCATAGGCTCAATGTTGATTTTAGTCTACAGTATGTTTACTGCTTTTTTCTTTATTGATAA
AGTCTTTACTAATATCATTTATTTTCAAGGCATGTTTTATACCCAGATTTTTGGGATTCCCGTATTTATCTTTTTAAATT
TAATCGTTATCTTTCTTTGTATCATTGTAGGTAGCGTACTTGCCTATAAAATCAATCAACAAAATGATTGGTTGAAGCAA
CAAATTGAACGTGCATTTGAAGGGGAAACAGTAGGGATCAATGACCAACATATCGAATTATATAATGAGACGATTGAACT
GTATCAAGCCCTTGTTCCTTTGAATCAAGAACTTCATAAAATGCGTATTAAAACTCAAAATTTAACGAACGAATCTTATA
ATATGAACGATTTGAAAGTGAAAAAAATAATTGAAGATGAGAGACAACGGTTGGCTAGGGAATTACACGATAGTGTGTCC
CAACAACTCTTTGCGGCAAGCATGATGTTATCCGCGATTAAAGAAACAGAGTTAACCCCACCACTCGATCAGCAAATTCC
AACTTTAGAGAAAATGGTCCAAGATTCTCAGTTGGAGATGCGGGCGTTATTGTTACATTTGAGACCGATAGGACTTAAAG
ACCGCTCGTTAGGTGAAGGTATTAAATCATTAGTTACAGATCTACAAAGAAAAGTTCCAATGAAAGTTGTACAAGAAATT
GACGAATTTGAAGTGCCAAAAGGGATAGAAGACCACTTATTTCGAATCACTCAAGAAGCCATCTCTAATACATTACGTCA
TGCTAAAGGGAAACAAGTTACTGTCGAATTGCTCAATCGTGAAGACTATTTATTGTTGCGTATTCAAGATGACGGTATCG
GTTTTAATGTAGATGACAAATTAGAGCAAAGTTATGGACTTAAAAATATGCGTGAACGTGCAATAGAAATCGGGGCAACC
TTTCATATCGTTTCATTGCCAGACGCTGGGACGAGAATAGAAGTAAAGGCACCACTTGATAAGGAGGTACATAATGACAA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

3D structure

• AlphaFold DB: A0A0K1ACB9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	84.438	100	0.844