Detailed information NTG0670871

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MUA28_RS04865
• Genome accession: NZ_CP094707
• Coordinates: 1077676..1078719 (+)
• Length: 347 a.a.
• NCBI ID: WP_002481663.1
• Uniprot ID: -
• Organism: Staphylococcus simulans strain IVB6192
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1072676..1083719

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA28_RS04840 (MUA28_04830)	-	1073679..1074398 (+)	720	WP_023015863.1	type 1 glutamine amidotransferase	-
MUA28_RS04845 (MUA28_04835)	-	1074481..1075467 (-)	987	WP_002481667.1	aromatic acid exporter family protein	-
MUA28_RS04850 (MUA28_04840)	map	1075687..1076451 (+)	765	WP_002481666.1	type I methionyl aminopeptidase	-
MUA28_RS04855 (MUA28_04845)	-	1076567..1076962 (+)	396	WP_002481665.1	hypothetical protein	-
MUA28_RS04860 (MUA28_04850)	liaF	1076978..1077679 (+)	702	WP_002481664.1	cell wall-active antibiotics response protein LiaF	-
MUA28_RS04865 (MUA28_04855)	vraS	1077676..1078719 (+)	1044	WP_002481663.1	sensor histidine kinase	Regulator
MUA28_RS04870 (MUA28_04860)	vraR	1078709..1079338 (+)	630	WP_002481662.1	response regulator transcription factor	Regulator
MUA28_RS04875 (MUA28_04865)	-	1079409..1079987 (-)	579	WP_002481661.1	carbonic anhydrase	-
MUA28_RS04880 (MUA28_04870)	-	1080183..1081259 (-)	1077	WP_262556405.1	YihY/virulence factor BrkB family protein	-
MUA28_RS04885 (MUA28_04875)	-	1081390..1081680 (-)	291	WP_002481659.1	hypothetical protein	-
MUA28_RS04890 (MUA28_04880)	-	1081688..1082152 (-)	465	WP_023015860.1	low molecular weight protein-tyrosine-phosphatase	-
MUA28_RS04895 (MUA28_04885)	-	1082376..1082582 (+)	207	WP_002481657.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39897.15 Da
• Isoelectric Point: 4.8944

>NTDB_id=670871 MUA28_RS04865 WP_002481663.1 1077676..1078719(+) (vraS) [Staphylococcus simulans strain IVB6192]
MNHYIRAIGSMLILNYSILAIFFFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNIIVILMSIIVGSVLAYKVNEQNDWIKT
QIEHSIEGEVVGINDQNIELYQETLDIYHTLVPLNQELHRLRIKTQDLTNETYNLNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESPLEPPLDQQIPTLEKMVQDSQLEMRALLLHLRPLGLKDRSLGEGIKDLVVDLQKKVPMKVVYDI
EDFEVPKGIEDHLFRITQEGISNTLRHAEGTKLTIDLFNKDDYLLLRIQDDGKGFDVDEKMEKSYGLKNMRERALEIGAT
LHIVSLPGAGTRIEVKAPLNKEENDGD

Nucleotide

• Length: 1044 bp

>NTDB_id=670871 MUA28_RS04865 WP_002481663.1 1077676..1078719(+) (vraS) [Staphylococcus simulans strain IVB6192]
ATGAACCACTATATCAGAGCCATCGGTTCGATGCTGATATTGAACTATAGTATATTAGCGATTTTCTTTTTTATAGACAA
AGTATTCGTCAACATCATCTACTTTCAAGGAATGTTTTACACGCAGATTTTCGGCATTCCTGTTTTCTTGTTTTTAAATA
TTATAGTGATTTTGATGAGTATTATTGTTGGTTCTGTGTTAGCGTATAAAGTGAACGAACAAAATGATTGGATTAAAACA
CAAATTGAACATTCCATTGAAGGGGAAGTTGTCGGTATTAATGATCAAAATATCGAACTCTACCAAGAAACTTTGGATAT
CTATCATACACTTGTGCCATTAAACCAAGAATTACATCGACTACGTATTAAAACACAAGATTTGACCAACGAAACATATA
ATTTAAATGACGTTAAAGTGAAGAAAATTATAGAAGATGAACGCCAGCGTTTAGCTAGAGAATTGCATGATTCAGTTAGT
CAGCAATTATTTGCGGCAAGTATGATGTTATCGGCGATTAAGGAATCACCACTTGAACCGCCGCTTGATCAGCAAATTCC
GACACTAGAAAAGATGGTACAAGATTCGCAACTAGAAATGCGTGCATTGTTATTACATTTAAGACCGCTTGGCTTAAAAG
ATCGCTCACTTGGGGAAGGAATTAAAGATCTTGTGGTGGACTTACAAAAGAAAGTGCCTATGAAAGTAGTTTATGATATT
GAAGACTTTGAGGTACCAAAAGGCATAGAAGATCATTTATTCCGTATCACCCAAGAAGGGATTTCCAATACACTGCGACA
TGCAGAAGGCACAAAATTAACGATAGATTTATTTAATAAAGATGATTATCTGTTATTGCGTATTCAAGATGATGGTAAAG
GCTTTGATGTAGATGAAAAAATGGAGAAAAGCTATGGATTGAAGAATATGCGAGAGCGAGCATTAGAAATCGGGGCAACA
CTGCATATTGTTTCTTTGCCTGGGGCAGGGACAAGAATTGAAGTGAAGGCTCCATTGAATAAGGAGGAAAATGATGGCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	86.167	100	0.862