Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   MUA28_RS04560 Genome accession   NZ_CP094707
Coordinates   1016796..1017512 (-) Length   238 a.a.
NCBI ID   WP_002481723.1    Uniprot ID   -
Organism   Staphylococcus simulans strain IVB6192     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1011796..1022512
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUA28_RS04540 (MUA28_04530) - 1012941..1013582 (+) 642 WP_002481727.1 redox-sensing transcriptional repressor Rex -
  MUA28_RS04545 (MUA28_04535) - 1013633..1013857 (-) 225 WP_002481726.1 sulfurtransferase TusA family protein -
  MUA28_RS04550 (MUA28_04540) - 1013913..1015001 (-) 1089 WP_070463416.1 YeeE/YedE family protein -
  MUA28_RS04555 (MUA28_04545) - 1015237..1016721 (+) 1485 WP_262571638.1 glycoside hydrolase family 32 protein -
  MUA28_RS04560 (MUA28_04550) agrA 1016796..1017512 (-) 717 WP_002481723.1 quorum-sensing response regulator AgrA Regulator
  MUA28_RS04565 (MUA28_04555) agrC 1017515..1018816 (-) 1302 WP_262571640.1 quorum-sensing sensor histidine kinase AgrC -
  MUA28_RS04570 (MUA28_04560) agrD 1018862..1018999 (-) 138 WP_002481721.1 cyclic lactone autoinducer peptide AgrD -
  MUA28_RS04575 (MUA28_04565) - 1018999..1019577 (-) 579 WP_002481720.1 accessory gene regulator AgrB -
  MUA28_RS04580 (MUA28_04570) - 1019889..1020053 (+) 165 WP_158257062.1 delta-lysin family phenol-soluble modulin -
  MUA28_RS04585 (MUA28_04575) - 1020358..1021158 (-) 801 WP_262571642.1 carbon-nitrogen family hydrolase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27762.55 Da        Isoelectric Point: 4.6392

>NTDB_id=670870 MUA28_RS04560 WP_002481723.1 1016796..1017512(-) (agrA) [Staphylococcus simulans strain IVB6192]
MKIIICEDDVQQREHIESIIENYIMIEEKPLEVALSTGDPYEVLEFAKATNEICCYFLDIQLDSDINGIKLGSELRNYDS
VGSIIFITSHSELTYLTFVYKVAAMDFIFKDDPSEMKSRIIDCIETALTRLQLLSKESSLETIELKRGSNSVYVNYDDVM
FFESSAKSHRLIAHLDNRQIEFYGNLKDLSQLDDRFFRCHNSYVINRNNIEEVISKEREVYFKNGEHCYISVRNLKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=670870 MUA28_RS04560 WP_002481723.1 1016796..1017512(-) (agrA) [Staphylococcus simulans strain IVB6192]
GTGAAGATTATTATATGCGAAGATGATGTACAACAGCGTGAACACATTGAATCCATCATTGAAAATTATATTATGATTGA
AGAAAAACCTTTAGAAGTGGCGCTCTCAACGGGCGATCCTTATGAGGTATTAGAATTCGCTAAAGCTACAAATGAGATTT
GTTGTTACTTCTTAGATATTCAGTTAGATTCTGATATTAACGGTATTAAGCTTGGCAGCGAACTTAGAAACTATGATTCT
GTCGGCAGTATTATCTTTATTACTAGCCACAGTGAACTCACTTATCTTACTTTCGTTTATAAAGTAGCAGCCATGGACTT
TATTTTTAAAGATGACCCTTCAGAAATGAAATCTCGAATTATTGATTGTATCGAAACTGCATTGACGAGACTACAGTTGC
TTTCAAAAGAATCTAGTCTCGAAACAATTGAGTTAAAACGTGGCAGTAACTCAGTCTATGTTAATTACGATGATGTCATG
TTCTTTGAATCCTCGGCAAAATCACATCGTTTAATTGCGCATTTAGACAATCGTCAAATCGAATTTTATGGCAACTTAAA
AGATTTAAGCCAATTAGATGACCGCTTCTTCCGTTGTCACAATAGTTACGTCATTAATCGCAATAACATCGAAGAAGTAA
TATCTAAAGAACGTGAGGTCTACTTTAAAAATGGTGAACACTGTTATATCTCAGTAAGAAATTTAAAGAAAATCTAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

79.412

100

0.794