Detailed information NTG0670841

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MUA57_RS04945
• Genome accession: NZ_CP094706
• Coordinates: 1101174..1102217 (+)
• Length: 347 a.a.
• NCBI ID: WP_002481663.1
• Uniprot ID: -
• Organism: Staphylococcus simulans strain IVB6193
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1096174..1107217

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA57_RS04920 (MUA57_04920)	-	1097177..1097896 (+)	720	WP_070848237.1	type 1 glutamine amidotransferase	-
MUA57_RS04925 (MUA57_04925)	-	1097979..1098965 (-)	987	WP_002481667.1	aromatic acid exporter family protein	-
MUA57_RS04930 (MUA57_04930)	map	1099185..1099949 (+)	765	WP_060803962.1	type I methionyl aminopeptidase	-
MUA57_RS04935 (MUA57_04935)	-	1100065..1100460 (+)	396	WP_002481665.1	hypothetical protein	-
MUA57_RS04940 (MUA57_04940)	liaF	1100476..1101177 (+)	702	WP_002481664.1	cell wall-active antibiotics response protein LiaF	-
MUA57_RS04945 (MUA57_04945)	vraS	1101174..1102217 (+)	1044	WP_002481663.1	sensor histidine kinase	Regulator
MUA57_RS04950 (MUA57_04950)	vraR	1102207..1102836 (+)	630	WP_002481662.1	response regulator transcription factor	Regulator
MUA57_RS04955 (MUA57_04955)	-	1102907..1103485 (-)	579	WP_002481661.1	carbonic anhydrase	-
MUA57_RS04960 (MUA57_04960)	-	1103693..1104769 (-)	1077	WP_002481660.1	YihY/virulence factor BrkB family protein	-
MUA57_RS04965 (MUA57_04965)	-	1104900..1105190 (-)	291	WP_002481659.1	hypothetical protein	-
MUA57_RS04970 (MUA57_04970)	-	1105198..1105662 (-)	465	WP_023015860.1	low molecular weight protein-tyrosine-phosphatase	-
MUA57_RS04975 (MUA57_04975)	-	1105886..1106092 (+)	207	WP_002481657.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39897.15 Da
• Isoelectric Point: 4.8944

>NTDB_id=670841 MUA57_RS04945 WP_002481663.1 1101174..1102217(+) (vraS) [Staphylococcus simulans strain IVB6193]
MNHYIRAIGSMLILNYSILAIFFFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNIIVILMSIIVGSVLAYKVNEQNDWIKT
QIEHSIEGEVVGINDQNIELYQETLDIYHTLVPLNQELHRLRIKTQDLTNETYNLNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESPLEPPLDQQIPTLEKMVQDSQLEMRALLLHLRPLGLKDRSLGEGIKDLVVDLQKKVPMKVVYDI
EDFEVPKGIEDHLFRITQEGISNTLRHAEGTKLTIDLFNKDDYLLLRIQDDGKGFDVDEKMEKSYGLKNMRERALEIGAT
LHIVSLPGAGTRIEVKAPLNKEENDGD

Nucleotide

• Length: 1044 bp

>NTDB_id=670841 MUA57_RS04945 WP_002481663.1 1101174..1102217(+) (vraS) [Staphylococcus simulans strain IVB6193]
ATGAACCACTATATCAGAGCCATCGGTTCGATGCTGATATTGAACTATAGTATATTAGCGATTTTCTTTTTTATAGACAA
AGTATTCGTCAACATCATCTACTTTCAAGGAATGTTTTACACGCAGATTTTCGGCATTCCTGTTTTCTTATTTTTAAATA
TTATAGTGATTTTGATGAGTATTATTGTTGGTTCTGTGTTAGCGTATAAAGTGAACGAACAAAATGATTGGATTAAAACA
CAAATTGAACATTCCATTGAAGGGGAAGTTGTCGGTATTAATGATCAAAATATCGAACTCTACCAAGAAACTTTGGATAT
CTATCATACACTTGTGCCATTAAACCAAGAGTTACATCGACTACGTATTAAAACACAAGATTTGACCAACGAAACATATA
ATTTAAATGACGTTAAAGTGAAGAAAATTATAGAAGATGAACGCCAGCGTTTAGCTAGAGAATTGCATGATTCAGTTAGT
CAGCAATTATTTGCGGCAAGTATGATGTTATCGGCGATTAAGGAATCACCACTTGAACCGCCGCTTGATCAGCAAATTCC
GACACTAGAAAAGATGGTACAAGATTCGCAACTAGAAATGCGTGCATTGTTATTACATTTAAGACCGCTTGGCTTAAAAG
ATCGCTCACTTGGGGAAGGAATTAAAGATCTTGTTGTGGACTTACAAAAGAAAGTGCCTATGAAAGTAGTTTATGATATT
GAAGACTTTGAGGTACCAAAAGGCATAGAAGATCATTTATTCCGTATCACCCAAGAAGGGATTTCCAATACACTGCGACA
TGCAGAAGGCACAAAATTAACGATAGATTTATTTAATAAAGATGATTATCTGTTATTGCGTATTCAAGATGATGGTAAAG
GCTTTGATGTAGATGAAAAAATGGAGAAAAGCTATGGATTGAAGAATATGCGAGAGCGAGCATTAGAAATCGGGGCAACA
CTGCATATTGTTTCTTTGCCTGGGGCAGGGACAAGAATTGAAGTGAAGGCTCCATTGAATAAGGAGGAAAATGATGGCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	86.167	100	0.862