Detailed information NTG0670813

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MUA54_RS05050
• Genome accession: NZ_CP094704
• Coordinates: 1130397..1131440 (+)
• Length: 347 a.a.
• NCBI ID: WP_002481663.1
• Uniprot ID: -
• Organism: Staphylococcus simulans strain IVB6207
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1125397..1136440

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA54_RS05025 (MUA54_05015)	-	1126400..1127119 (+)	720	WP_023015863.1	type 1 glutamine amidotransferase	-
MUA54_RS05030 (MUA54_05020)	-	1127202..1128188 (-)	987	WP_002481667.1	aromatic acid exporter family protein	-
MUA54_RS05035 (MUA54_05025)	map	1128408..1129172 (+)	765	WP_002481666.1	type I methionyl aminopeptidase	-
MUA54_RS05040 (MUA54_05030)	-	1129288..1129683 (+)	396	WP_002481665.1	hypothetical protein	-
MUA54_RS05045 (MUA54_05035)	liaF	1129699..1130400 (+)	702	WP_002481664.1	cell wall-active antibiotics response protein LiaF	-
MUA54_RS05050 (MUA54_05040)	vraS	1130397..1131440 (+)	1044	WP_002481663.1	sensor histidine kinase	Regulator
MUA54_RS05055 (MUA54_05045)	vraR	1131430..1132059 (+)	630	WP_002481662.1	response regulator transcription factor	Regulator
MUA54_RS05060 (MUA54_05050)	-	1132130..1132708 (-)	579	WP_002481661.1	carbonic anhydrase	-
MUA54_RS05065 (MUA54_05055)	-	1132916..1133992 (-)	1077	WP_002481660.1	YihY/virulence factor BrkB family protein	-
MUA54_RS05070 (MUA54_05060)	-	1134123..1134413 (-)	291	WP_002481659.1	hypothetical protein	-
MUA54_RS05075 (MUA54_05065)	-	1134421..1134885 (-)	465	WP_023015860.1	low molecular weight protein-tyrosine-phosphatase	-
MUA54_RS05080 (MUA54_05070)	-	1135109..1135315 (+)	207	WP_002481657.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39897.15 Da
• Isoelectric Point: 4.8944

>NTDB_id=670813 MUA54_RS05050 WP_002481663.1 1130397..1131440(+) (vraS) [Staphylococcus simulans strain IVB6207]
MNHYIRAIGSMLILNYSILAIFFFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNIIVILMSIIVGSVLAYKVNEQNDWIKT
QIEHSIEGEVVGINDQNIELYQETLDIYHTLVPLNQELHRLRIKTQDLTNETYNLNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESPLEPPLDQQIPTLEKMVQDSQLEMRALLLHLRPLGLKDRSLGEGIKDLVVDLQKKVPMKVVYDI
EDFEVPKGIEDHLFRITQEGISNTLRHAEGTKLTIDLFNKDDYLLLRIQDDGKGFDVDEKMEKSYGLKNMRERALEIGAT
LHIVSLPGAGTRIEVKAPLNKEENDGD

Nucleotide

• Length: 1044 bp

>NTDB_id=670813 MUA54_RS05050 WP_002481663.1 1130397..1131440(+) (vraS) [Staphylococcus simulans strain IVB6207]
ATGAACCACTATATCAGAGCCATCGGTTCGATGCTGATATTGAACTATAGTATTTTAGCGATTTTCTTTTTTATAGACAA
AGTATTCGTCAACATCATCTACTTTCAAGGAATGTTTTACACGCAGATTTTCGGCATTCCTGTTTTCTTATTTTTAAATA
TTATAGTAATTTTGATGAGTATTATTGTTGGTTCTGTGTTAGCGTATAAAGTGAACGAACAAAATGATTGGATTAAAACA
CAAATTGAACATTCCATTGAAGGGGAAGTTGTCGGTATTAATGATCAAAATATCGAACTCTACCAAGAAACTTTGGATAT
CTATCATACACTTGTGCCATTAAACCAAGAATTACATCGACTACGTATTAAAACACAAGATTTGACCAACGAAACATATA
ATTTAAATGACGTTAAAGTGAAGAAAATTATAGAAGATGAACGCCAGCGTTTAGCTAGGGAATTGCATGATTCAGTTAGT
CAGCAATTATTTGCGGCAAGTATGATGTTATCGGCGATTAAGGAATCACCACTTGAACCGCCGCTTGATCAGCAAATTCC
GACATTAGAAAAGATGGTACAAGATTCGCAACTAGAAATGCGTGCATTGTTATTACATTTAAGACCGCTTGGCTTAAAAG
ATCGCTCACTTGGGGAAGGAATTAAAGATCTTGTGGTGGACTTACAAAAGAAAGTGCCTATGAAAGTAGTTTATGATATT
GAAGACTTTGAGGTACCAAAAGGCATAGAAGATCATTTATTCCGTATCACCCAAGAAGGGATTTCCAATACACTGCGACA
TGCAGAAGGCACAAAATTAACGATAGATTTATTTAATAAAGATGATTATCTGTTATTGCGTATTCAAGATGATGGTAAAG
GCTTTGATGTAGATGAAAAAATGGAGAAAAGCTATGGATTGAAGAATATGCGAGAGCGAGCATTAGAAATTGGGGCAACA
CTGCATATTGTTTCTTTGCCTGGAGCAGGGACAAGAATTGAAGTGAAGGCTCCATTGAATAAGGAGGAAAATGATGGCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	86.167	100	0.862