Detailed information NTG0670782

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MUA41_RS05095
• Genome accession: NZ_CP094702
• Coordinates: 1124938..1125981 (+)
• Length: 347 a.a.
• NCBI ID: WP_002481663.1
• Uniprot ID: -
• Organism: Staphylococcus simulans strain IVB6209
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1119938..1130981

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA41_RS05070 (MUA41_05065)	-	1120941..1121660 (+)	720	WP_070848237.1	type 1 glutamine amidotransferase	-
MUA41_RS05075 (MUA41_05070)	-	1121743..1122729 (-)	987	WP_002481667.1	aromatic acid exporter family protein	-
MUA41_RS05080 (MUA41_05075)	map	1122949..1123713 (+)	765	WP_002481666.1	type I methionyl aminopeptidase	-
MUA41_RS05085 (MUA41_05080)	-	1123829..1124224 (+)	396	WP_002481665.1	hypothetical protein	-
MUA41_RS05090 (MUA41_05085)	liaF	1124240..1124941 (+)	702	WP_002481664.1	cell wall-active antibiotics response protein LiaF	-
MUA41_RS05095 (MUA41_05090)	vraS	1124938..1125981 (+)	1044	WP_002481663.1	sensor histidine kinase	Regulator
MUA41_RS05100 (MUA41_05095)	vraR	1125971..1126600 (+)	630	WP_002481662.1	response regulator transcription factor	Regulator
MUA41_RS05105 (MUA41_05100)	-	1126671..1127249 (-)	579	WP_002481661.1	carbonic anhydrase	-
MUA41_RS05110 (MUA41_05105)	-	1127457..1128533 (-)	1077	WP_262556405.1	YihY/virulence factor BrkB family protein	-
MUA41_RS05115 (MUA41_05110)	-	1128664..1128954 (-)	291	WP_002481659.1	hypothetical protein	-
MUA41_RS05120 (MUA41_05115)	-	1128962..1129426 (-)	465	WP_023015860.1	low molecular weight protein-tyrosine-phosphatase	-
MUA41_RS05125 (MUA41_05120)	-	1129650..1129856 (+)	207	WP_002481657.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39897.15 Da
• Isoelectric Point: 4.8944

>NTDB_id=670782 MUA41_RS05095 WP_002481663.1 1124938..1125981(+) (vraS) [Staphylococcus simulans strain IVB6209]
MNHYIRAIGSMLILNYSILAIFFFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNIIVILMSIIVGSVLAYKVNEQNDWIKT
QIEHSIEGEVVGINDQNIELYQETLDIYHTLVPLNQELHRLRIKTQDLTNETYNLNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESPLEPPLDQQIPTLEKMVQDSQLEMRALLLHLRPLGLKDRSLGEGIKDLVVDLQKKVPMKVVYDI
EDFEVPKGIEDHLFRITQEGISNTLRHAEGTKLTIDLFNKDDYLLLRIQDDGKGFDVDEKMEKSYGLKNMRERALEIGAT
LHIVSLPGAGTRIEVKAPLNKEENDGD

Nucleotide

• Length: 1044 bp

>NTDB_id=670782 MUA41_RS05095 WP_002481663.1 1124938..1125981(+) (vraS) [Staphylococcus simulans strain IVB6209]
ATGAACCACTATATCAGAGCCATCGGTTCGATGCTGATATTGAACTATAGTATATTAGCGATTTTCTTTTTTATAGACAA
AGTATTCGTCAACATCATCTACTTTCAAGGAATGTTTTACACGCAGATTTTCGGCATTCCTGTTTTCTTGTTTTTAAATA
TTATAGTGATTTTGATGAGTATTATTGTTGGTTCTGTGTTAGCGTATAAAGTGAACGAACAAAATGATTGGATTAAAACA
CAAATTGAACATTCCATTGAAGGGGAAGTTGTCGGTATTAATGATCAAAATATCGAACTCTACCAAGAAACTTTGGATAT
CTATCATACACTTGTGCCATTAAACCAAGAATTACATCGACTACGTATTAAAACACAAGATTTGACCAACGAAACATATA
ATTTAAATGACGTTAAAGTGAAGAAAATTATAGAAGATGAACGCCAGCGTTTAGCTAGAGAATTGCATGATTCAGTTAGT
CAGCAATTATTTGCGGCAAGTATGATGTTATCGGCGATTAAGGAATCACCACTTGAACCGCCGCTTGATCAGCAAATTCC
GACACTAGAAAAGATGGTACAAGATTCGCAACTAGAAATGCGTGCATTGTTATTACATTTAAGACCGCTTGGCTTAAAAG
ATCGCTCACTTGGGGAAGGAATTAAAGATCTTGTTGTGGACTTACAAAAGAAAGTGCCTATGAAAGTAGTTTATGATATT
GAAGACTTTGAGGTACCAAAAGGCATAGAAGATCATTTATTCCGTATCACCCAAGAAGGGATTTCCAATACACTGCGACA
TGCAGAAGGCACAAAATTAACGATAGATTTATTTAATAAAGATGATTATCTGTTATTGCGTATTCAAGATGATGGTAAAG
GCTTTGATGTAGATGAAAAAATGGAGAAAAGCTATGGATTGAAGAATATGCGAGAGCGAGCATTAGAAATCGGGGCAACA
CTGCATATTGTTTCTTTGCCTGGGGCAGGGACAAGAATTGAAGTGAAGGCTCCATTGAATAAGGAGGAAAATGATGGCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	86.167	100	0.862