Detailed information NTG0670750

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MUA31_RS04985
• Genome accession: NZ_CP094698
• Coordinates: 1100980..1102023 (+)
• Length: 347 a.a.
• NCBI ID: WP_002481663.1
• Uniprot ID: -
• Organism: Staphylococcus simulans strain IVB6241
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1095980..1107023

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA31_RS04960 (MUA31_04965)	-	1096984..1097703 (+)	720	WP_070848237.1	type 1 glutamine amidotransferase	-
MUA31_RS04965 (MUA31_04970)	-	1097786..1098772 (-)	987	WP_002481667.1	aromatic acid exporter family protein	-
MUA31_RS04970 (MUA31_04975)	map	1098991..1099755 (+)	765	WP_002481666.1	type I methionyl aminopeptidase	-
MUA31_RS04975 (MUA31_04980)	-	1099871..1100266 (+)	396	WP_002481665.1	hypothetical protein	-
MUA31_RS04980 (MUA31_04985)	liaF	1100282..1100983 (+)	702	WP_002481664.1	cell wall-active antibiotics response protein LiaF	-
MUA31_RS04985 (MUA31_04990)	vraS	1100980..1102023 (+)	1044	WP_002481663.1	sensor histidine kinase	Regulator
MUA31_RS04990 (MUA31_04995)	vraR	1102013..1102642 (+)	630	WP_002481662.1	response regulator transcription factor	Regulator
MUA31_RS04995 (MUA31_05000)	-	1102713..1103291 (-)	579	WP_002481661.1	carbonic anhydrase	-
MUA31_RS05000 (MUA31_05005)	-	1103499..1104575 (-)	1077	WP_057510596.1	YihY/virulence factor BrkB family protein	-
MUA31_RS05005 (MUA31_05010)	-	1104706..1104996 (-)	291	WP_002481659.1	hypothetical protein	-
MUA31_RS05010 (MUA31_05015)	-	1105004..1105468 (-)	465	WP_023015860.1	low molecular weight protein-tyrosine-phosphatase	-
MUA31_RS05015 (MUA31_05020)	-	1105692..1105898 (+)	207	WP_262547376.1	DUF1128 domain-containing protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39897.15 Da
• Isoelectric Point: 4.8944

>NTDB_id=670750 MUA31_RS04985 WP_002481663.1 1100980..1102023(+) (vraS) [Staphylococcus simulans strain IVB6241]
MNHYIRAIGSMLILNYSILAIFFFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNIIVILMSIIVGSVLAYKVNEQNDWIKT
QIEHSIEGEVVGINDQNIELYQETLDIYHTLVPLNQELHRLRIKTQDLTNETYNLNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESPLEPPLDQQIPTLEKMVQDSQLEMRALLLHLRPLGLKDRSLGEGIKDLVVDLQKKVPMKVVYDI
EDFEVPKGIEDHLFRITQEGISNTLRHAEGTKLTIDLFNKDDYLLLRIQDDGKGFDVDEKMEKSYGLKNMRERALEIGAT
LHIVSLPGAGTRIEVKAPLNKEENDGD

Nucleotide

• Length: 1044 bp

>NTDB_id=670750 MUA31_RS04985 WP_002481663.1 1100980..1102023(+) (vraS) [Staphylococcus simulans strain IVB6241]
ATGAACCACTATATCAGAGCCATCGGTTCGATGCTGATATTGAACTATAGTATATTAGCGATTTTCTTTTTTATAGACAA
AGTATTCGTCAACATCATCTACTTTCAAGGAATGTTTTACACGCAGATTTTCGGCATTCCTGTTTTCTTATTTTTAAATA
TTATAGTGATTTTGATGAGTATTATTGTTGGTTCTGTGTTAGCGTATAAAGTGAACGAACAAAATGATTGGATTAAAACA
CAAATCGAACATTCCATTGAAGGGGAAGTTGTCGGTATTAATGATCAAAATATCGAACTCTACCAAGAAACTTTGGATAT
CTATCACACACTTGTGCCATTAAACCAAGAATTACATCGACTACGTATTAAAACACAAGATTTGACCAATGAAACATATA
ATTTAAATGACGTTAAAGTGAAGAAAATTATAGAAGATGAACGCCAGCGTTTAGCTAGAGAATTGCATGATTCAGTTAGT
CAGCAATTATTTGCGGCAAGTATGATGTTATCGGCGATTAAGGAATCACCACTTGAACCGCCGCTTGATCAGCAAATTCC
GACACTAGAAAAGATGGTACAAGATTCGCAACTAGAAATGCGTGCATTGTTATTACATTTAAGACCGCTTGGCTTAAAAG
ATCGCTCACTTGGGGAAGGAATTAAAGATCTTGTTGTGGACTTACAAAAGAAAGTGCCTATGAAAGTAGTTTATGATATT
GAAGACTTTGAGGTACCAAAAGGCATAGAAGATCATTTATTCCGTATCACCCAAGAAGGGATTTCCAATACACTGCGACA
TGCAGAAGGCACAAAATTAACGATAGATTTATTTAATAAAGATGATTATCTGTTATTGCGTATTCAAGATGATGGTAAAG
GCTTTGATGTAGATGAAAAAATGGAGAAAAGCTATGGATTGAAGAATATGCGAGAGCGAGCATTAGAAATTGGGGCAACA
CTGCATATTGTTTCTTTGCCTGGGGCAGGGACAAGAATTGAAGTGAAGGCTCCATTGAATAAGGAGGAAAATGATGGCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	86.167	100	0.862