Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   MUA73_RS04830 Genome accession   NZ_CP094696
Coordinates   1060172..1060888 (-) Length   238 a.a.
NCBI ID   WP_262557882.1    Uniprot ID   -
Organism   Staphylococcus simulans strain IVB6251     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1055172..1065888
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUA73_RS04810 (MUA73_04805) - 1056317..1056958 (+) 642 WP_002481727.1 redox-sensing transcriptional repressor Rex -
  MUA73_RS04815 (MUA73_04810) - 1057009..1057233 (-) 225 WP_002481726.1 sulfurtransferase TusA family protein -
  MUA73_RS04820 (MUA73_04815) - 1057289..1058377 (-) 1089 WP_070463416.1 YeeE/YedE family protein -
  MUA73_RS04825 (MUA73_04820) - 1058613..1060097 (+) 1485 WP_262557881.1 glycoside hydrolase family 32 protein -
  MUA73_RS04830 (MUA73_04825) agrA 1060172..1060888 (-) 717 WP_262557882.1 quorum-sensing response regulator AgrA Regulator
  MUA73_RS13195 agrC 1060891..1062192 (-) 1302 WP_002481722.1 quorum-sensing sensor histidine kinase AgrC -
  MUA73_RS04840 (MUA73_04835) agrD 1062238..1062375 (-) 138 WP_002481721.1 cyclic lactone autoinducer peptide AgrD -
  MUA73_RS04845 (MUA73_04840) - 1062375..1062953 (-) 579 WP_002481720.1 accessory gene regulator AgrB -
  MUA73_RS04850 (MUA73_04845) - 1063265..1063429 (+) 165 WP_158257062.1 delta-lysin family phenol-soluble modulin -
  MUA73_RS04855 (MUA73_04850) - 1063734..1064534 (-) 801 WP_107587542.1 carbon-nitrogen family hydrolase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27746.55 Da        Isoelectric Point: 4.6392

>NTDB_id=670688 MUA73_RS04830 WP_262557882.1 1060172..1060888(-) (agrA) [Staphylococcus simulans strain IVB6251]
MKIIICEDDVQQREHIESIIENYIMIEEKPLEVALSTGDPYEVLEFAKATNEICCYFLDIQLDSDINGIKLGSELRNYDS
VGSIIFITSHSELTYLTFVYKVAAMDFIFKDDPSEMKSRIIDCIETALTRLQLLSKESSLETIELKRGSNSVFVNYDDVM
FFESSAKSHRLIAHLDNRQIEFYGNLKDLSQLDDRFFRCHNSYVINRNNIEEVISKEREVYFKNGEHCYISVRNLKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=670688 MUA73_RS04830 WP_262557882.1 1060172..1060888(-) (agrA) [Staphylococcus simulans strain IVB6251]
GTGAAGATTATTATATGCGAAGATGATGTACAACAGCGTGAACACATTGAATCCATCATTGAAAATTATATTATGATTGA
AGAAAAACCTTTAGAAGTGGCGCTCTCAACGGGTGATCCTTATGAGGTATTAGAATTCGCTAAAGCTACAAATGAGATTT
GTTGTTACTTCTTAGATATTCAGTTAGATTCTGATATTAACGGTATTAAGCTTGGCAGCGAACTTAGAAACTATGATTCT
GTCGGCAGTATTATCTTTATTACTAGCCACAGTGAACTCACTTATCTTACTTTCGTTTATAAAGTAGCAGCCATGGACTT
TATTTTTAAAGATGACCCTTCAGAAATGAAATCTCGAATTATTGATTGTATCGAAACTGCATTGACGAGACTACAGTTGC
TTTCAAAAGAATCTAGTCTCGAAACAATTGAGTTAAAACGTGGCAGTAACTCAGTCTTTGTTAATTACGATGATGTTATG
TTCTTTGAATCCTCGGCAAAATCACATCGCTTAATTGCGCATTTAGACAATCGTCAAATCGAATTTTATGGCAACTTAAA
AGATTTAAGCCAATTAGATGACCGCTTCTTCCGTTGTCACAATAGTTACGTCATTAATCGCAATAACATCGAAGAAGTAA
TATCTAAAGAACGTGAGGTCTACTTTAAAAATGGTGAACACTGTTATATCTCAGTAAGAAATTTAAAGAAAATCTAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

78.992

100

0.79