Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrB   Type   Machinery gene
Locus tag   MUA73_RS00190 Genome accession   NZ_CP094696
Coordinates   41950..43578 (-) Length   542 a.a.
NCBI ID   WP_262557420.1    Uniprot ID   -
Organism   Staphylococcus simulans strain IVB6251     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 31334..49117 41950..43578 within 0


Gene organization within MGE regions


Location: 31334..49117
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUA73_RS00140 (MUA73_00140) - 31781..32464 (+) 684 WP_262557411.1 hypothetical protein -
  MUA73_RS13150 - 32666..32761 (+) 96 Protein_26 hypothetical protein -
  MUA73_RS00145 (MUA73_00145) - 32864..33973 (+) 1110 WP_394371772.1 four-carbon acid sugar kinase family protein -
  MUA73_RS00150 (MUA73_00150) - 33970..34110 (+) 141 WP_262557413.1 hypothetical protein -
  MUA73_RS00155 (MUA73_00155) - 34129..35491 (+) 1363 Protein_29 gluconate:H+ symporter -
  MUA73_RS00160 (MUA73_00160) - 36338..37075 (+) 738 WP_262557414.1 GntR family transcriptional regulator -
  MUA73_RS00165 (MUA73_00165) deoD 37417..38124 (+) 708 WP_262557415.1 purine-nucleoside phosphorylase -
  MUA73_RS00170 (MUA73_00170) - 38137..39492 (+) 1356 WP_262557417.1 MFS transporter -
  MUA73_RS00175 (MUA73_00175) deoC 39506..40168 (+) 663 WP_262557418.1 deoxyribose-phosphate aldolase -
  MUA73_RS00180 (MUA73_00180) deoB 40197..41375 (+) 1179 WP_262557419.1 phosphopentomutase -
  MUA73_RS00185 (MUA73_00185) - 41421..41549 (-) 129 Protein_35 NAD-dependent protein deacylase -
  MUA73_RS00190 (MUA73_00190) ccrB 41950..43578 (-) 1629 WP_262557420.1 cassette chromosome recombinase CcrB Machinery gene
  MUA73_RS00195 (MUA73_00195) ccrA 43600..44951 (-) 1352 Protein_37 cassette chromosome recombinase CcrA -
  MUA73_RS00200 (MUA73_00200) cch1 45451..47239 (-) 1789 Protein_38 cassette chromosome replicative helicase -
  MUA73_RS00205 (MUA73_00205) - 47364..48751 (-) 1388 Protein_39 DUF6038 family protein -

Sequence

Protein


Download         Length: 542 a.a.        Molecular weight: 62660.64 Da        Isoelectric Point: 9.6801

>NTDB_id=670685 MUA73_RS00190 WP_262557420.1 41950..43578(-) (ccrB) [Staphylococcus simulans strain IVB6251]
MQQLKQKRVGIYVRVSTEIQSAEGYSIDGQINQIKEYCNFHHFEVKDIYADRGISGKSMNRPELQRMLHDANEGLIDCVM
VYKTNRLARNTSDLLKIVEDLHRQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
IPLGYDKTPDNKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGNPFSINSITYILVNPFYIGKIQFAK
YKDWNEKRRKGLNDKPIIADGKHPPIISQELWDKVQSRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSKLRNKGSKVCSANSVRADVIEKYVMDQILEIVKSDKVINKVLERVNQENKVDIGALNHDIAYKQQQFD
EIQAKLNNLVKTIEDNPDLTSVLKETIHQYETQLNDITNQMNQLKQQQNQEKPSYDTKQIALLLQRIFQNIESMDKSHLK
ALYLTVIDRIDIRKDGNHKKQFYVTLKLNNEIIKQLFNNTQLDEVLLSTSSLFLPQTLYFQI

Nucleotide


Download         Length: 1629 bp        

>NTDB_id=670685 MUA73_RS00190 WP_262557420.1 41950..43578(-) (ccrB) [Staphylococcus simulans strain IVB6251]
ATGCAACAACTCAAACAAAAACGTGTCGGTATCTATGTTCGTGTATCAACGGAAATCCAAAGTGCTGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATATTGTAACTTTCATCATTTCGAGGTCAAAGATATATACGCCGATCGTGGTA
TATCAGGAAAGTCTATGAACCGTCCTGAACTTCAACGTATGTTACATGATGCAAATGAAGGTCTCATCGATTGTGTCATG
GTATATAAAACAAATCGACTCGCACGTAATACATCAGACTTACTCAAAATTGTTGAAGACCTTCATCGTCAAAATGTCGA
ATTCTTCAGCTTATCTGAACGTATGGAAGTCAATACTTCTTCTGGTAAGCTCATGTTACAAATACTTGCGAGCTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAACGTATTCATGGGACAAACCAGACGTGCTCAAGAAGGCTATTATCAAGGCAAT
ATTCCACTAGGATATGACAAAACACCTGATAATAAACACGAACTGATGATTAATCAACATGAAGCGAATATCGTGAAATA
TATATTCGAATCTTATGCCAAAGGACATGGTTATCGTAAAATTGCCAATGCCCTCAATCACAAAGGATATGTTACTAAAA
AAGGTAATCCTTTTAGCATCAATTCAATAACCTATATCTTAGTCAATCCATTCTACATTGGTAAAATTCAATTTGCGAAG
TATAAAGATTGGAATGAAAAGCGTCGTAAAGGACTGAATGATAAACCTATTATAGCTGATGGTAAACACCCTCCTATTAT
TAGTCAAGAATTATGGGATAAAGTCCAATCACGCAAAAAACAGGTCAGTCAAAAACCTCAAGTTCATGGTAAAGGAACCA
ATCTATTAACAGGTATTATTCACTGTCCACAATGCGGCGCACCTATGGCGGCAAGTAATACCACTAATACACTCAAAGAT
GGAACTAAGAAACGTATTCGCTATTATTCTTGTAGTAAACTCCGAAACAAAGGCTCAAAAGTATGTTCTGCGAATAGCGT
TAGAGCTGATGTTATCGAAAAGTATGTTATGGATCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTAATAAAGTCT
TAGAACGTGTCAATCAAGAGAATAAAGTCGATATTGGTGCATTGAACCATGATATTGCTTATAAGCAACAACAATTTGAT
GAAATACAAGCTAAATTAAATAATTTGGTTAAAACTATTGAAGATAATCCAGACTTAACGTCCGTACTCAAAGAAACCAT
ACACCAATATGAAACGCAACTCAATGATATCACAAACCAAATGAATCAACTCAAGCAGCAACAAAATCAAGAGAAACCAT
CTTATGATACGAAACAAATCGCTCTCCTATTACAACGAATATTTCAAAACATAGAATCCATGGATAAATCACATCTTAAA
GCATTATACCTTACGGTCATTGATCGTATTGATATTCGTAAAGATGGGAATCATAAAAAGCAATTCTATGTCACACTCAA
GCTCAATAATGAGATTATTAAACAACTTTTCAATAATACTCAGCTCGACGAAGTGCTTCTCAGCACTTCGTCTTTATTTT
TGCCTCAAACACTCTACTTTCAAATCTAA

Domains

Predicted by InterproScan.

Recombinase (Recombinase)

(180-280)

Resolvase, N terminal domain (Resolvase)

(11-156)

Ogr/Delta-like zinc finger (Ogr_Delta)

(301-356)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrB Staphylococcus aureus N315

86.9

100

0.869