Detailed information NTG0670567

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MT995_RS07075
• Genome accession: NZ_CP094663
• Coordinates: 1430636..1431679 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 494
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1425636..1436679

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MT995_RS07045 (MT995_07045)	-	1426057..1427313 (-)	1257	WP_001795108.1	aminopeptidase	-
MT995_RS07050 (MT995_07050)	-	1427316..1427516 (-)	201	WP_000180460.1	DUF1128 family protein	-
MT995_RS07055 (MT995_07055)	-	1427663..1428127 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
MT995_RS07060 (MT995_07060)	-	1428134..1428409 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
MT995_RS07065 (MT995_07065)	-	1428687..1429904 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
MT995_RS07070 (MT995_07070)	vraR	1430017..1430646 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
MT995_RS07075 (MT995_07075)	vraS	1430636..1431679 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
MT995_RS07080 (MT995_07080)	liaF	1431676..1432377 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
MT995_RS07085 (MT995_07085)	-	1432392..1432778 (-)	387	WP_001110179.1	hypothetical protein	-
MT995_RS07090 (MT995_07090)	map	1432995..1433753 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
MT995_RS07095 (MT995_07095)	-	1434284..1435270 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
MT995_RS07100 (MT995_07100)	-	1435701..1436114 (-)	414	WP_001557448.1	hypothetical protein	-
MT995_RS07105 (MT995_07105)	-	1436143..1436253 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=670567 MT995_RS07075 WP_001017131.1 1430636..1431679(-) (vraS) [Staphylococcus aureus strain 494]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=670567 MT995_RS07075 WP_001017131.1 1430636..1431679(-) (vraS) [Staphylococcus aureus strain 494]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1