Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   MTX16_RS14975 Genome accession   NZ_CP094624
Coordinates   2913598..2916033 (+) Length   811 a.a.
NCBI ID   WP_000971183.1    Uniprot ID   A0A9Q5MSH6
Organism   Bacillus thuringiensis strain LX43     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 2908598..2921033
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MTX16_RS14960 ctsR 2911326..2911787 (+) 462 WP_001244565.1 transcriptional regulator CtsR -
  MTX16_RS14965 - 2911958..2912506 (+) 549 WP_000128399.1 UvrB/UvrC motif-containing protein -
  MTX16_RS14970 - 2912511..2913575 (+) 1065 WP_017673990.1 protein arginine kinase -
  MTX16_RS14975 clpC 2913598..2916033 (+) 2436 WP_000971183.1 ATP-dependent protease ATP-binding subunit ClpC Regulator
  MTX16_RS14980 radA 2916129..2917505 (+) 1377 WP_001085202.1 DNA repair protein RadA Machinery gene
  MTX16_RS14985 disA 2917509..2918582 (+) 1074 WP_000392163.1 DNA integrity scanning diadenylate cyclase DisA -
  MTX16_RS14990 - 2918743..2919852 (+) 1110 WP_000919677.1 PIN/TRAM domain-containing protein -
  MTX16_RS14995 ispD 2919869..2920549 (+) 681 WP_000288284.1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase -

Sequence

Protein


Download         Length: 811 a.a.        Molecular weight: 90572.42 Da        Isoelectric Point: 6.4057

>NTDB_id=670281 MTX16_RS14975 WP_000971183.1 2913598..2916033(+) (clpC) [Bacillus thuringiensis strain LX43]
MMFGRFTERAQKVLALSQEEAIRIGHNNIGTEHILLGLVREGEGIAAKALIALGLSPEKVQKEVEALIGRGTEASQTVHY
TPRAKKVIELSMDEARKLGHSYVGTEHILLGLIREGEGVAARVLNNLGVSLNKARQQVLQLLGSNEASSGHQGGSSTNAN
TPTLDSLARDLTVVARENRLDPVIGRSKEIQRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQQIVNNEVPETLRDKRV
MTLDMGTVVAGTKYRGEFEDRLKKVMDEIRQAGNIILFIDELHTLIGAGGAEGAIDASNILKPSLARGELQCIGATTLDE
YRKYIEKDAALERRFQPIHVDEPSLEESTQILKGLRDRYEAHHRVSITDDAIDAAVKLSDRYITDRFLPDKAIDLIDEAA
SKVRLRSYTTPPNLKELEVKLEEIRKEKDAAVQSQEFEKAASLRDMEQRLREKLEDTKRQWKEQQGKENSEVTVEDIANV
VSTWTRIPVSKLAQTETDKLLNLESILHDRVIGQDEAVVAVAKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALA
ESMFGDEDAMIRIDMSEYMEKHSTSRLVGSPPGYVGYEEGGQLTEKVRRKPYSVVLLDEVEKAHPDVFNILLQVLEDGRL
TDSKGRTVDFRNTIVIMTSNVGAEALKRNKHLGFNVQDESRDYSDMKGKVMDELKKAFRPEFLNRIDEIIVFHMLEKKHI
QEIVTLMVNQLVNRLKEQEIELHLTEGAIAAIADKGFDREYGARPLRRAIQKHVEDRLSEELLKGAIEKGQKVIFDVEGE
TFVIHSAEKVK

Nucleotide


Download         Length: 2436 bp        

>NTDB_id=670281 MTX16_RS14975 WP_000971183.1 2913598..2916033(+) (clpC) [Bacillus thuringiensis strain LX43]
ATGATGTTTGGAAGATTTACAGAAAGAGCACAGAAAGTATTAGCTTTATCTCAAGAGGAAGCAATTCGCATTGGGCATAA
TAACATTGGAACAGAACATATTTTACTTGGGCTTGTACGCGAAGGTGAAGGAATTGCAGCAAAAGCGTTAATTGCTCTTG
GATTGAGCCCGGAGAAAGTGCAAAAAGAGGTAGAAGCGTTAATTGGACGTGGAACAGAAGCTTCTCAAACTGTACATTAT
ACACCTCGTGCTAAAAAAGTTATTGAATTGTCTATGGATGAAGCGCGTAAGCTAGGACATTCTTATGTTGGAACAGAACA
TATTTTACTTGGCTTAATCCGTGAAGGTGAAGGTGTAGCGGCACGTGTATTAAATAATTTAGGTGTAAGCCTCAACAAAG
CAAGACAACAAGTGTTACAACTTCTTGGAAGTAACGAAGCAAGTTCAGGTCACCAAGGTGGTTCATCGACAAATGCAAAT
ACACCGACACTAGACAGTTTAGCGCGCGACTTAACAGTTGTTGCACGTGAGAATCGTTTGGATCCTGTTATTGGACGTAG
TAAAGAAATTCAACGTGTAATTGAAGTGTTAAGCCGTAGAACAAAAAACAATCCAGTGTTAATTGGAGAGCCTGGTGTAG
GTAAAACAGCAATTGCTGAAGGGTTAGCACAGCAAATCGTAAATAATGAAGTTCCTGAAACGTTAAGAGATAAGCGTGTT
ATGACACTAGATATGGGAACAGTGGTAGCTGGGACGAAATATCGTGGTGAGTTTGAAGATCGTTTAAAGAAAGTAATGGA
TGAAATACGTCAAGCAGGGAATATTATTCTATTTATTGATGAACTTCATACATTAATCGGTGCAGGTGGAGCAGAAGGTG
CAATCGATGCATCGAATATTTTAAAACCATCTTTAGCACGCGGAGAATTACAATGTATTGGTGCGACAACTTTAGATGAG
TATCGTAAATATATTGAAAAGGATGCAGCTTTAGAGAGACGTTTCCAGCCAATTCATGTTGATGAGCCGAGTCTAGAAGA
ATCAACTCAAATCTTGAAAGGGTTACGCGATCGTTATGAGGCGCATCACCGTGTGTCTATTACAGATGATGCAATTGATG
CAGCTGTAAAACTTTCAGATCGTTATATTACGGATCGTTTCTTACCAGATAAAGCAATTGATTTAATTGATGAAGCTGCT
TCAAAAGTTCGCTTGCGTTCTTATACAACACCACCAAACTTAAAAGAGCTTGAAGTGAAGCTTGAGGAAATTCGAAAAGA
AAAAGATGCGGCTGTACAAAGTCAAGAGTTTGAAAAGGCTGCTTCCTTACGTGATATGGAACAACGCTTACGTGAGAAAT
TGGAAGATACAAAGCGTCAGTGGAAAGAACAACAAGGAAAAGAAAATTCAGAGGTTACGGTAGAAGATATTGCAAATGTC
GTTTCTACATGGACACGTATCCCTGTTTCTAAACTTGCACAAACAGAGACTGATAAATTATTAAACTTAGAATCCATTCT
TCATGATCGTGTCATCGGTCAGGATGAAGCTGTAGTGGCTGTAGCGAAAGCTGTTCGTCGTGCAAGAGCAGGACTGAAAG
ATCCGAAACGTCCAATTGGTTCATTTATTTTCTTAGGGCCAACAGGTGTAGGTAAAACAGAATTAGCAAGAGCATTGGCA
GAATCTATGTTCGGTGATGAGGATGCAATGATTCGCATTGATATGTCTGAGTATATGGAGAAACATTCAACTTCTCGCTT
AGTTGGTTCTCCTCCAGGATATGTTGGGTATGAAGAAGGCGGACAATTAACAGAGAAGGTTCGTCGTAAGCCTTATTCAG
TTGTCCTATTAGATGAAGTAGAGAAGGCACATCCTGATGTATTTAATATTCTACTACAGGTATTGGAAGATGGTCGTTTA
ACTGATTCTAAAGGACGTACAGTTGATTTCCGTAATACGATTGTTATTATGACGTCTAACGTTGGTGCTGAGGCGTTAAA
ACGTAACAAACATCTTGGATTTAACGTACAAGATGAAAGCCGTGATTATTCGGATATGAAAGGTAAAGTAATGGATGAGC
TGAAAAAGGCATTTCGTCCAGAATTCTTAAACCGTATTGATGAAATTATCGTATTCCATATGCTTGAGAAAAAACATATT
CAAGAAATTGTGACTCTTATGGTAAATCAGTTAGTGAATCGCTTAAAAGAACAAGAAATTGAATTGCACTTAACAGAAGG
AGCGATTGCAGCTATTGCTGATAAAGGGTTTGATCGTGAATATGGTGCTCGTCCACTACGTAGAGCAATTCAGAAGCATG
TAGAAGATAGACTATCGGAAGAACTTTTAAAAGGTGCTATTGAGAAAGGTCAAAAAGTTATCTTTGATGTAGAAGGGGAA
ACATTTGTCATTCATAGTGCTGAAAAGGTAAAATAA

Domains

Predicted by InterproScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(206-318)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(715-793)

AAA domain (Cdc48 subfamily) (AAA_2)

(537-709)

AAA lid domain (AAA_lid_9)

(345-446)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(18-69)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(93-143)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Bacillus subtilis subsp. subtilis str. 168

86.049

99.877

0.859
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

50.375

98.644

0.497
  clpC Streptococcus thermophilus LMD-9

45.969

100

0.471
  clpC Streptococcus mutans UA159

45

100

0.466
  clpC Streptococcus thermophilus LMG 18311

45.476

100

0.465
  clpC Streptococcus pneumoniae D39

46.675

98.274

0.459
  clpC Streptococcus pneumoniae Rx1

46.675

98.274

0.459
  clpC Streptococcus pneumoniae TIGR4

46.375

98.644

0.457
  clpE Streptococcus mutans UA159

53.538

80.148

0.429
  clpE Streptococcus pneumoniae R6

52.55

79.778

0.419
  clpE Streptococcus pneumoniae TIGR4

52.55

79.778

0.419
  clpE Streptococcus pneumoniae Rx1

52.55

79.778

0.419
  clpE Streptococcus pneumoniae D39

52.55

79.778

0.419
  clpC Lactococcus lactis subsp. cremoris KW2

51.735

78.175

0.404