Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   MTP23_RS14260 Genome accession   NZ_CP094443
Coordinates   2858014..2858730 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain N10CSA27     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2853014..2863730
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MTP23_RS14240 (MTP23_14240) - 2854106..2855056 (+) 951 WP_000790331.1 LacI family DNA-binding transcriptional regulator -
  MTP23_RS14245 (MTP23_14245) - 2855205..2856689 (+) 1485 WP_000141432.1 glycoside hydrolase family 32 protein -
  MTP23_RS14250 (MTP23_14250) - 2856686..2857645 (+) 960 WP_001253312.1 carbohydrate kinase -
  MTP23_RS14255 (MTP23_14255) - 2857833..2857942 (-) 110 Protein_2779 hypothetical protein -
  MTP23_RS14260 (MTP23_14260) agrA 2858014..2858730 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  MTP23_RS14265 (MTP23_14265) agrC 2858749..2860032 (-) 1284 WP_228653083.1 quorum-sensing sensor histidine kinase AgrC -
  MTP23_RS14270 (MTP23_14270) agrD 2860062..2860205 (-) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  MTP23_RS14275 (MTP23_14275) - 2860208..2860771 (-) 564 WP_001105696.1 accessory gene regulator ArgB-like protein -
  MTP23_RS14280 (MTP23_14280) hld 2861061..2861141 (+) 81 WP_000046022.1 delta-hemolysin -
  MTP23_RS14285 (MTP23_14285) - 2861741..2862526 (-) 786 WP_000867951.1 carbon-nitrogen family hydrolase -
  MTP23_RS14290 (MTP23_14290) - 2862887..2863513 (-) 627 WP_000522381.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=669522 MTP23_RS14260 WP_000688492.1 2858014..2858730(-) (agrA) [Staphylococcus aureus strain N10CSA27]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=669522 MTP23_RS14260 WP_000688492.1 2858014..2858730(-) (agrA) [Staphylococcus aureus strain N10CSA27]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment