Detailed information NTG0669518

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: MTP23_RS11120
• Genome accession: NZ_CP094443
• Coordinates: 2238972..2239859 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain N10CSA27
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2233972..2244859

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MTP23_RS11090 (MTP23_11090)	-	2234707..2235468 (+)	762	WP_000323441.1	alpha/beta hydrolase family protein	-
MTP23_RS11095 (MTP23_11095)	-	2235713..2236168 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
MTP23_RS14885	-	2236290..2236391 (+)	102	WP_000731976.1	SE2200 family small protein	-
MTP23_RS11105 (MTP23_11105)	-	2236451..2237872 (-)	1422	WP_117201430.1	alkaline phosphatase	-
MTP23_RS11110 (MTP23_11110)	-	2238070..2238270 (+)	201	WP_000604730.1	hypothetical protein	-
MTP23_RS11115 (MTP23_11115)	braR	2238296..2238961 (+)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
MTP23_RS11120 (MTP23_11120)	braS	2238972..2239859 (+)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
MTP23_RS11125 (MTP23_11125)	-	2239967..2240722 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
MTP23_RS11130 (MTP23_11130)	-	2240719..2242719 (+)	2001	WP_000776751.1	ABC transporter permease	-
MTP23_RS11135 (MTP23_11135)	-	2243378..2243491 (+)	114	Protein_2167	hypothetical protein	-
MTP23_RS11140 (MTP23_11140)	-	2243873..2244133 (+)	261	WP_001791974.1	hypothetical protein	-
MTP23_RS11145 (MTP23_11145)	-	2244143..2244640 (+)	498	WP_001065268.1	glutathione peroxidase	-
MTP23_RS11150 (MTP23_11150)	-	2244748..2244840 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=669518 MTP23_RS11120 WP_000143425.1 2238972..2239859(+) (braS) [Staphylococcus aureus strain N10CSA27]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=669518 MTP23_RS11120 WP_000143425.1 2238972..2239859(+) (braS) [Staphylococcus aureus strain N10CSA27]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1