Detailed information NTG0668667

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: MRS49_RS10065
• Genome accession: NZ_CP094294
• Coordinates: 1944405..1946837 (+)
• Length: 810 a.a.
• NCBI ID: WP_015239036.1
• Uniprot ID: -
• Organism: Bacillus velezensis strain AP3
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1939405..1951837

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MRS49_RS10050	ctsR	1942282..1942746 (+)	465	WP_003156396.1	transcriptional regulator CtsR	-
MRS49_RS10055	-	1942760..1943317 (+)	558	WP_007410387.1	UvrB/UvrC motif-containing protein	-
MRS49_RS10060	-	1943317..1944408 (+)	1092	WP_003156398.1	protein arginine kinase	-
MRS49_RS10065	clpC	1944405..1946837 (+)	2433	WP_015239036.1	ATP-dependent protease ATP-binding subunit ClpC	Regulator
MRS49_RS10070	radA	1946931..1948310 (+)	1380	WP_014304212.1	DNA repair protein RadA	Machinery gene
MRS49_RS10075	disA	1948314..1949396 (+)	1083	WP_007615225.1	DNA integrity scanning diadenylate cyclase DisA	-
MRS49_RS10080	-	1949510..1950610 (+)	1101	WP_003156403.1	PIN/TRAM domain-containing protein	-
MRS49_RS10085	ispD	1950623..1951321 (+)	699	WP_032872229.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
MRS49_RS10090	ispF	1951314..1951790 (+)	477	WP_003156407.1	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	-

Sequence

Protein

• Length: 810 a.a.
• Molecular weight: 90040.49 Da
• Isoelectric Point: 5.9514

>NTDB_id=668667 MRS49_RS10065 WP_015239036.1 1944405..1946837(+) (clpC) [Bacillus velezensis strain AP3]
MMFGRFTERAQKVLALAQEEALRLGHNNIGTEHILLGLVREGEGIAAKALQALGLGSDKIQKEVESLIGRGQEMSQTIHY
TPRAKKVIELSMDEARKLGHSYVGTEHILLGLIREGEGVAARVLNNLGVSLNKARQQVLQLLGSNETGSSASGTNSNANT
PTLDSLARDLTAIAKEDSLDPVIGRSKEIQRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQQIINNEVPEILRDKRVM
TLDMGTVVAGTKYRGEFEDRLKKVMDEIRQAGNIILFIDELHTLIGAGGAEGAIDASNILKPSLARGELQCIGATTLDEY
RKYIEKDAALERRFQPIQVDQPSADESIQILKGLRDRYEAHHRVSITDEAIEAAVKLSDRYISDRFLPDKAIDLIDEAGS
KVRLRSFTTPPNLKELEQKLDEVRKEKDAAVQSQEFEKAASLRDTEQRLREQVEDTKKTWKEKQGQENSEVSVEDIAMVV
SSWTGVPVSKIAQTETDKLLNMENILHSRVIGQDEAVVAVAKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALAE
SIFGDEEAMIRVDMSEYMEKHSTSRLVGSPPGYVGYDEGGQLTEKVRRKPYSVVLLDEIEKAHPDVFNILLQVLEDGRLT
DSKGRTVDFRNTILIMTSNVGASELKRNKYVGFNVQDESQNHKDMKDKVMGELKRAFRPEFINRIDEIIVFHSLEKKHLT
DIVSLMSDQLTKRLKEQDLSIELTDAAKAKVAEEGVDLEYGARPLRRAIQKHVEDRLSEELLRGNIDKGQHIVLDVEDGE
FVVKTTAKTN

Nucleotide

• Length: 2433 bp

>NTDB_id=668667 MRS49_RS10065 WP_015239036.1 1944405..1946837(+) (clpC) [Bacillus velezensis strain AP3]
ATGATGTTTGGAAGGTTTACAGAGCGAGCTCAAAAGGTATTGGCACTGGCACAGGAAGAAGCACTGCGCTTAGGCCATAA
CAATATTGGAACTGAACATATCTTATTAGGTCTGGTTCGTGAAGGAGAAGGGATTGCGGCTAAAGCACTCCAAGCACTCG
GACTCGGTTCGGATAAAATTCAGAAAGAAGTGGAGAGCTTAATCGGACGGGGACAGGAAATGTCTCAAACGATTCATTAT
ACGCCAAGAGCAAAAAAAGTCATTGAGCTCAGCATGGATGAAGCCAGAAAGCTAGGACATTCTTATGTGGGAACAGAACA
CATACTTCTCGGACTGATTCGTGAAGGAGAAGGCGTGGCCGCGAGAGTTCTGAATAATCTCGGTGTCAGCTTGAATAAGG
CGAGACAGCAAGTGCTGCAGCTTCTGGGAAGCAATGAGACGGGATCTTCTGCATCCGGTACGAACAGCAATGCAAACACG
CCGACGCTTGACAGCTTGGCTCGTGATTTAACTGCGATTGCGAAGGAAGACAGTCTTGATCCGGTTATCGGCCGAAGCAA
AGAGATTCAGCGTGTTATTGAGGTATTAAGCCGCAGAACGAAGAATAATCCCGTTCTTATCGGAGAACCGGGTGTAGGTA
AGACTGCGATTGCTGAAGGCCTCGCACAGCAGATCATCAATAATGAAGTGCCGGAAATTTTACGTGATAAACGCGTAATG
ACATTAGACATGGGTACGGTTGTAGCCGGTACGAAATACCGCGGAGAATTTGAAGACCGCTTGAAAAAAGTAATGGATGA
AATACGTCAGGCCGGCAATATTATTTTATTCATTGACGAACTGCATACACTGATCGGAGCGGGGGGAGCAGAAGGTGCGA
TTGACGCATCGAATATCTTAAAACCTTCACTGGCCCGCGGAGAGCTTCAATGCATCGGTGCGACAACGCTTGATGAATAC
CGTAAATATATCGAAAAAGACGCTGCTCTGGAGCGCCGTTTCCAGCCGATTCAGGTGGATCAGCCGTCAGCCGATGAAAG
CATTCAAATTTTAAAAGGGCTCCGTGACCGCTATGAAGCGCATCACCGCGTATCCATTACCGATGAAGCGATTGAAGCAG
CGGTAAAATTGTCCGACCGTTATATTTCTGACCGCTTCCTTCCGGATAAAGCGATCGATTTAATTGATGAAGCCGGTTCA
AAAGTACGTCTCCGTTCTTTCACAACGCCTCCGAACTTAAAAGAGCTTGAGCAGAAACTCGATGAAGTTCGCAAGGAAAA
AGACGCTGCCGTTCAGAGCCAGGAGTTTGAAAAAGCGGCTTCTCTTCGTGATACGGAGCAGCGCCTGAGAGAACAGGTGG
AAGACACGAAAAAAACGTGGAAAGAAAAACAAGGCCAGGAGAACTCCGAAGTTTCTGTAGAGGATATCGCGATGGTTGTA
TCCAGCTGGACCGGGGTGCCTGTATCTAAAATTGCCCAAACGGAAACAGATAAGCTTCTCAATATGGAAAACATTCTGCA
CTCCCGCGTCATCGGCCAGGATGAAGCTGTTGTAGCCGTTGCAAAGGCTGTCAGACGTGCAAGAGCCGGTCTGAAGGACC
CGAAACGCCCGATTGGTTCATTCATCTTCTTAGGCCCTACAGGCGTTGGGAAGACAGAGCTGGCACGAGCGCTGGCGGAA
TCCATTTTCGGTGATGAGGAAGCGATGATCAGAGTGGATATGTCCGAATACATGGAGAAACACTCGACTTCACGTCTTGT
CGGTTCTCCTCCGGGATATGTCGGCTATGATGAAGGCGGCCAGCTGACAGAAAAAGTGAGAAGAAAACCTTACTCTGTCG
TACTGCTTGATGAAATTGAAAAAGCGCATCCTGATGTGTTTAACATTCTCCTGCAAGTGCTTGAAGACGGACGCTTGACT
GATTCAAAAGGACGCACTGTGGATTTCCGCAACACGATCCTGATTATGACGTCAAACGTCGGAGCGAGCGAGCTGAAACG
CAACAAATATGTGGGCTTCAATGTGCAGGATGAATCACAAAACCATAAAGACATGAAAGACAAAGTCATGGGAGAGCTGA
AGCGCGCCTTCAGACCTGAGTTTATCAACCGGATTGACGAAATTATCGTCTTCCACTCCCTTGAGAAAAAACATCTTACA
GACATCGTGTCGCTTATGTCTGATCAGTTAACAAAACGTCTGAAAGAACAAGATCTCTCTATCGAGCTGACGGATGCTGC
AAAAGCAAAAGTGGCAGAAGAGGGCGTCGATTTGGAATACGGCGCACGTCCGTTAAGAAGAGCGATTCAAAAGCATGTGG
AGGACCGGTTATCAGAAGAACTCCTCAGAGGCAATATTGATAAAGGCCAGCACATTGTTCTTGATGTTGAGGACGGCGAA
TTTGTCGTAAAAACAACTGCTAAAACGAACTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (536-708)

• AAA lid domain (AAA_lid_9) (343-444)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (714-793)

• ATPase family associated with various cellular activities (AAA) (AAA) (205-317)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-69)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (93-143)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	98.395	100	0.984
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	49.875	98.765	0.493
clpC	Streptococcus thermophilus LMD-9	46.723	100	0.475
clpC	Streptococcus thermophilus LMG 18311	46.481	100	0.473
clpC	Streptococcus pneumoniae Rx1	45.117	99.877	0.451
clpC	Streptococcus pneumoniae D39	45.117	99.877	0.451
clpC	Streptococcus mutans UA159	43.947	100	0.448
clpC	Streptococcus pneumoniae TIGR4	44.87	99.877	0.448
clpE	Streptococcus mutans UA159	53.313	80.123	0.427
clpC	Lactococcus lactis subsp. cremoris KW2	49.709	84.938	0.422
clpE	Streptococcus pneumoniae TIGR4	52.388	80.123	0.42
clpE	Streptococcus pneumoniae Rx1	52.388	80.123	0.42
clpE	Streptococcus pneumoniae D39	52.388	80.123	0.42
clpE	Streptococcus pneumoniae R6	52.388	80.123	0.42