Detailed information    

insolico Bioinformatically predicted

Overview

Name   treR   Type   Regulator
Locus tag   MP387_RS01470 Genome accession   NZ_CP094226
Coordinates   290935..291648 (-) Length   237 a.a.
NCBI ID   WP_242747166.1    Uniprot ID   -
Organism   Streptococcus oralis strain 1648     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 276304..305386 290935..291648 within 0


Gene organization within MGE regions


Location: 276304..305386
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MP387_RS01420 (MP387_01420) - 278639..279115 (-) 477 WP_242747162.1 glutathione peroxidase -
  MP387_RS01425 (MP387_01425) - 279112..279690 (-) 579 WP_139658334.1 DUF3278 domain-containing protein -
  MP387_RS01430 (MP387_01430) - 279703..280044 (-) 342 WP_139658335.1 hypothetical protein -
  MP387_RS01435 (MP387_01435) - 280055..280597 (-) 543 WP_139658336.1 DUF3278 domain-containing protein -
  MP387_RS01440 (MP387_01440) - 280613..280807 (-) 195 WP_001082470.1 helix-turn-helix transcriptional regulator -
  MP387_RS01445 (MP387_01445) rsmH 280970..281920 (+) 951 WP_000159431.1 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH -
  MP387_RS01450 (MP387_01450) ftsL 281931..282248 (+) 318 WP_000840795.1 cell division protein FtsL -
  MP387_RS01455 (MP387_01455) pbp2X 282252..284507 (+) 2256 WP_125413317.1 penicillin-binding protein PBP2X -
  MP387_RS01460 (MP387_01460) mraY 284509..285489 (+) 981 WP_125413316.1 phospho-N-acetylmuramoyl-pentapeptide- transferase -
  MP387_RS01465 (MP387_01465) - 285559..290682 (-) 5124 WP_242747164.1 SIALI-17 repeat-containing surface protein -
  MP387_RS01470 (MP387_01470) treR 290935..291648 (-) 714 WP_242747166.1 trehalose operon repressor Regulator
  MP387_RS01475 (MP387_01475) treP 291833..293800 (+) 1968 WP_242747168.1 PTS system trehalose-specific EIIBC component -
  MP387_RS01480 (MP387_01480) treC 293864..295495 (+) 1632 WP_242747169.1 alpha,alpha-phosphotrehalase -
  MP387_RS01485 (MP387_01485) - 295891..298521 (+) 2631 WP_242747171.1 SEC10/PgrA surface exclusion domain-containing protein -
  MP387_RS01490 (MP387_01490) - 298742..298987 (+) 246 WP_000364980.1 YneF family protein -
  MP387_RS01495 (MP387_01495) racE 299193..299987 (+) 795 WP_242747173.1 glutamate racemase -
  MP387_RS01500 (MP387_01500) - 299984..300955 (+) 972 WP_242747175.1 nucleoside-triphosphate diphosphatase -
  MP387_RS01505 (MP387_01505) - 300931..301452 (+) 522 WP_001118939.1 metallophosphoesterase -
  MP387_RS01510 (MP387_01510) cbpB 301449..301910 (+) 462 WP_000560696.1 cyclic-di-AMP-binding protein CbpB -
  MP387_RS01515 (MP387_01515) xerD 301907..302641 (+) 735 WP_278192658.1 site-specific tyrosine recombinase XerD -
  MP387_RS01520 (MP387_01520) - 302641..303390 (+) 750 WP_242747180.1 segregation/condensation protein A -
  MP387_RS01525 (MP387_01525) scpB 303387..303956 (+) 570 WP_000105289.1 SMC-Scp complex subunit ScpB -
  MP387_RS01530 (MP387_01530) - 303943..304665 (+) 723 WP_242747182.1 pseudouridine synthase -
  MP387_RS01535 (MP387_01535) yidD 304665..304907 (+) 243 WP_050251720.1 membrane protein insertion efficiency factor YidD -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 27740.80 Da        Isoelectric Point: 7.1434

>NTDB_id=668092 MP387_RS01470 WP_242747166.1 290935..291648(-) (treR) [Streptococcus oralis strain 1648]
MKKYQQLFKQIQKTIQNETYAIGDFLPSEHELMNQYQVSRDTVRKALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLT
SYQELVQELGLRSKTNVVSLDKIIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELVPNLTRQIAEQSIY
SYIEDDLKLHIDYAQKEITIDHTGDRDKILMDIGKDPYVVSIKSKVYLQDGHQFQFTESRHKLEKFHFVDFAKRHPK

Nucleotide


Download         Length: 714 bp        

>NTDB_id=668092 MP387_RS01470 WP_242747166.1 290935..291648(-) (treR) [Streptococcus oralis strain 1648]
ATGAAGAAATACCAACAATTATTTAAGCAAATCCAAAAAACCATTCAAAACGAGACCTACGCTATCGGAGATTTCCTCCC
CAGTGAGCACGAACTCATGAATCAGTATCAGGTGAGCCGTGACACCGTCCGAAAAGCTCTGTCCCTCCTCCAAGAGGAAG
GATTGATCAAAAAGATAAGGGGGCAAGGTTCCCAAGTCGTCAAAGAAGAAACGGTCAATTTCCCTGTCTCTAACCTAACC
AGCTACCAAGAACTGGTTCAGGAACTTGGGCTGCGCTCAAAAACCAATGTCGTCAGTCTGGACAAGATCATTATCGATAA
AAAGTCCTCACTGATAACCGGCTTCCCAGAGTTTCGGATGGTGTGGAAGGTGGTCCGCCAGCGTGTGGTGGATGATTTGG
TATCGGTTCTAGATACGGACTATCTGGATATGGAACTGGTCCCAAATCTCACTCGCCAAATCGCTGAGCAGTCTATCTAC
TCGTATATAGAGGACGACCTCAAACTCCATATTGATTATGCTCAGAAAGAAATCACCATTGACCACACGGGTGATCGAGA
CAAGATTCTCATGGACATTGGCAAAGACCCTTATGTCGTTTCAATCAAGTCAAAAGTCTATCTCCAAGACGGGCACCAGT
TCCAATTCACCGAAAGTCGCCATAAATTAGAAAAATTTCACTTTGTTGACTTTGCCAAAAGACATCCGAAATAA

Domains

Predicted by InterproScan.

UTRA domain (UTRA)

(89-226)

Bacterial regulatory proteins, gntR family (GntR)

(3-66)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  treR Streptococcus mutans UA159

57.872

99.156

0.574

Multiple sequence alignment