Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   MP387_RS01290 Genome accession   NZ_CP094226
Coordinates   245090..245914 (+) Length   274 a.a.
NCBI ID   WP_242747114.1    Uniprot ID   -
Organism   Streptococcus oralis strain 1648     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 240090..250914
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MP387_RS01255 (MP387_01255) asnA 240180..241172 (+) 993 WP_000747998.1 aspartate--ammonia ligase -
  MP387_RS01260 (MP387_01260) rsmD 241237..241776 (+) 540 WP_242747101.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  MP387_RS01265 (MP387_01265) coaD 241766..242254 (+) 489 WP_242747112.1 pantetheine-phosphate adenylyltransferase -
  MP387_RS01270 (MP387_01270) sepM 242238..243275 (+) 1038 WP_000730765.1 SepM family pheromone-processing serine protease Regulator
  MP387_RS01275 (MP387_01275) - 243331..243561 (+) 231 WP_009013716.1 DUF1146 family protein -
  MP387_RS01280 (MP387_01280) murA 243585..244868 (+) 1284 WP_000411918.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  MP387_RS01285 (MP387_01285) - 244855..245049 (+) 195 WP_000739701.1 DNA-directed RNA polymerase subunit beta -
  MP387_RS01290 (MP387_01290) endA 245090..245914 (+) 825 WP_242747114.1 DNA/RNA non-specific endonuclease Machinery gene
  MP387_RS01295 (MP387_01295) - 246050..247381 (+) 1332 WP_000390020.1 hemolysin family protein -
  MP387_RS01305 (MP387_01305) amiA3 247884..249863 (+) 1980 WP_242747116.1 peptide ABC transporter substrate-binding protein Regulator

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29957.54 Da        Isoelectric Point: 9.7190

>NTDB_id=668086 MP387_RS01290 WP_242747114.1 245090..245914(+) (endA) [Streptococcus oralis strain 1648]
MDKKTRQALIGLLLFLLLAAGSYYIKQMQSAPNSPRTKVNQKKQASEAPSQELAESVLTESIKNQIKGNLEWNGAGAFVV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANAILSKATRQYKNREETGNGSTSWTPPGWHQVKNLKGAYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEDSTGQNYYESLVRKALDQNKRVRYRVTLHYATNEDLVPSASQIE
AKSSDGELEFNVLIPNVQKGIQLDYQTGQVTVTD

Nucleotide


Download         Length: 825 bp        

>NTDB_id=668086 MP387_RS01290 WP_242747114.1 245090..245914(+) (endA) [Streptococcus oralis strain 1648]
ATGGACAAAAAAACAAGACAAGCTCTGATAGGATTACTTCTATTCTTACTCTTGGCTGCTGGAAGCTACTACATCAAGCA
GATGCAGTCAGCACCAAATAGCCCTAGAACCAAGGTTAATCAGAAAAAACAAGCTTCAGAAGCACCCAGTCAGGAGTTGG
CAGAAAGTGTCTTAACCGAGTCAATCAAAAACCAAATCAAGGGTAATCTCGAGTGGAATGGAGCAGGGGCCTTTGTTGTC
AATGGCAATAAAACCAATCTAGATGCCAAGGTTTCCAGCAAACCCTATGCGGATAATAAAACAAAGACAGTTGGAAAAGA
AACAGTCCCGACTGTTGCCAATGCCATCTTATCCAAAGCGACTCGGCAGTATAAGAATCGTGAAGAGACTGGAAATGGAT
CCACCTCTTGGACGCCACCAGGATGGCATCAGGTCAAGAATCTAAAGGGAGCCTATACACATGCAGTTGATAGAGGACAC
CTGCTGGGCTATGCCTTGATAGGTGGATTGGATGGTTTTGATGCCTCTACTAGCAATCCCAAGAACATTGCAGTCCAGAC
AGCTTGGGCAAACCAAGCACAGGCTGAAGATTCGACAGGTCAGAACTACTATGAGAGTTTGGTCAGAAAAGCCTTGGACC
AAAATAAGAGAGTCCGTTATCGGGTGACGCTCCACTATGCGACAAATGAGGACTTAGTTCCATCCGCTTCACAAATCGAA
GCCAAGTCTTCAGATGGCGAATTGGAATTCAATGTCCTAATCCCCAATGTTCAAAAGGGAATCCAGCTTGATTACCAAAC
GGGTCAAGTAACAGTGACAGATTAG

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(76-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

89.011

99.635

0.887
  endA Streptococcus pneumoniae D39

89.011

99.635

0.887
  endA Streptococcus pneumoniae R6

89.011

99.635

0.887
  endA Streptococcus pneumoniae TIGR4

89.011

99.635

0.887

Multiple sequence alignment