Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   MPG42_RS03105 Genome accession   NZ_CP094167
Coordinates   646290..648074 (-) Length   594 a.a.
NCBI ID   WP_245028893.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe0007     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 641290..653074
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG42_RS03075 (MPG42_03075) - 641880..642128 (+) 249 WP_000790557.1 RNA-binding protein -
  MPG42_RS03080 (MPG42_03080) - 642335..643156 (-) 822 WP_245028889.1 glycosyltransferase family 25 protein -
  MPG42_RS03085 (MPG42_03085) trxB 643319..644254 (-) 936 WP_120945573.1 thioredoxin-disulfide reductase -
  MPG42_RS03090 (MPG42_03090) trxA 644260..644580 (-) 321 WP_000020199.1 thioredoxin -
  MPG42_RS03095 (MPG42_03095) - 644669..645013 (-) 345 WP_001211669.1 YraN family protein -
  MPG42_RS03100 (MPG42_03100) - 645014..646279 (-) 1266 WP_245028891.1 homoserine dehydrogenase -
  MPG42_RS03105 (MPG42_03105) uvrC 646290..648074 (-) 1785 WP_245028893.1 excinuclease ABC subunit UvrC Machinery gene
  MPG42_RS03110 (MPG42_03110) - 648075..648536 (-) 462 WP_000437195.1 hypothetical protein -
  MPG42_RS03115 (MPG42_03115) - 648528..648707 (+) 180 WP_000468796.1 hypothetical protein -
  MPG42_RS03120 (MPG42_03120) - 648719..649360 (-) 642 WP_220883803.1 ATP-binding cassette domain-containing protein -
  MPG42_RS03125 (MPG42_03125) - 649364..651025 (-) 1662 WP_245028895.1 ABC transporter permease/substrate-binding protein -
  MPG42_RS03130 (MPG42_03130) - 651205..651642 (-) 438 WP_245028897.1 hypothetical protein -
  MPG42_RS03135 (MPG42_03135) motB 651646..652413 (-) 768 WP_154404919.1 flagellar motor protein MotB -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68766.09 Da        Isoelectric Point: 9.5333

>NTDB_id=667883 MPG42_RS03105 WP_245028893.1 646290..648074(-) (uvrC) [Helicobacter pylori strain Hpfe0007]
MADLLSSLKNLSHSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIHNNEITPNCRTSLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMECLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGSHKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQDFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARALFKLECMPYRVEIFDT
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYTQMSELLTRRALDFAKEPPPNLWVIDGGRVQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTANDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNTVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=667883 MPG42_RS03105 WP_245028893.1 646290..648074(-) (uvrC) [Helicobacter pylori strain Hpfe0007]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGTTATTTCTCTATCCACAATAATGAAATCACGCCCA
ATTGTCGCACAAGCTTACGAATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAACTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGATGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAAGATATTTTAGACAGCCTATATGAATTGCTTCCGTTAGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGTGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATAGTGGGAGCCATAAGGCAGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTTAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTAATGCCAGAACAGATTTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGATTTTATCTCTCACCAATACTCTAAAAAAATCGCTCTTAGTATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGAGCGCTCTTTAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCACGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTCGCCAAAGAAC
CACCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGTGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CCACACCGCTAACGATACTTTTAAATTACTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGCATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
TACCGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(384-538)

UvrB/uvrC motif (UVR)

(205-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.296

100

0.963

Multiple sequence alignment