Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   MPG84_RS00705 Genome accession   NZ_CP094164
Coordinates   151601..152344 (+) Length   247 a.a.
NCBI ID   WP_245059603.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe0012     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 146601..157344
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG84_RS00680 (MPG84_00680) panD 148751..149101 (+) 351 WP_180403071.1 aspartate 1-decarboxylase -
  MPG84_RS00685 (MPG84_00685) - 149112..149405 (+) 294 WP_000347916.1 YbaB/EbfC family nucleoid-associated protein -
  MPG84_RS00690 (MPG84_00690) - 149405..150400 (+) 996 WP_245060136.1 PDZ domain-containing protein -
  MPG84_RS00695 (MPG84_00695) comB6 150408..151463 (+) 1056 WP_245060138.1 P-type conjugative transfer protein TrbL Machinery gene
  MPG84_RS00700 (MPG84_00700) comB7 151479..151604 (+) 126 WP_001217867.1 hypothetical protein Machinery gene
  MPG84_RS00705 (MPG84_00705) comB8 151601..152344 (+) 744 WP_245059603.1 virB8 family protein Machinery gene
  MPG84_RS00710 (MPG84_00710) comB9 152344..153309 (+) 966 WP_245059604.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  MPG84_RS00715 (MPG84_00715) comB10 153302..154438 (+) 1137 WP_245059605.1 DNA type IV secretion system protein ComB10 Machinery gene
  MPG84_RS00720 (MPG84_00720) - 154508..155920 (+) 1413 WP_245059606.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  MPG84_RS00725 (MPG84_00725) gmd 155935..157080 (+) 1146 WP_245059607.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28712.97 Da        Isoelectric Point: 8.9546

>NTDB_id=667833 MPG84_RS00705 WP_245059603.1 151601..152344(+) (comB8) [Helicobacter pylori strain Hpfe0012]
MKEKPFNSEQLIYLEELLNHQEKHLENKLSGFSVSDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAIVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
VQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLMNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKVTRYSITEI
APTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=667833 MPG84_RS00705 WP_245059603.1 151601..152344(+) (comB8) [Helicobacter pylori strain Hpfe0012]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAATTGATCTATTTAGAAGAGCTTTTAAACCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAGTGATTTGGACATGCAAAGCGTGTTTAGATTAGAGAGAAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGCTTGATGAGTTTTATCGCTCTTGTTTTAGCGATCGTTTTAATCAGTGTTTTACCCCTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAAGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAATCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAGGATTTGATCAAAACGCAAAACAGCATTTAT
GTGCAAAGCCATTTGGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
CTCCATTGCAGCTAAACTCATGAACGAAAACAAGCTGGTGTATGAAAAGCGTTATAAAATCGTGCTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAGTTACTCGCTACAGCATCACTGAAATC
GCGCCGACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

97.571

100

0.976

Multiple sequence alignment