Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   MPG52_RS04755 Genome accession   NZ_CP094157
Coordinates   1014015..1015799 (+) Length   594 a.a.
NCBI ID   WP_245076251.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe0021     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1009015..1020799
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG52_RS04720 (MPG52_04720) - 1009174..1009416 (+) 243 Protein_934 osmoprotection protein -
  MPG52_RS04725 (MPG52_04725) - 1009430..1010002 (-) 573 WP_180385878.1 Hpy99I family type II restriction endonuclease -
  MPG52_RS04730 (MPG52_04730) - 1009996..1010814 (-) 819 WP_000125522.1 site-specific DNA-methyltransferase -
  MPG52_RS04735 (MPG52_04735) - 1011065..1012726 (+) 1662 WP_245076247.1 glycine betaine ABC transporter substrate-binding protein -
  MPG52_RS04740 (MPG52_04740) - 1012729..1013379 (+) 651 WP_180452149.1 ATP-binding cassette domain-containing protein -
  MPG52_RS04745 (MPG52_04745) - 1013382..1013561 (-) 180 WP_000468793.1 hypothetical protein -
  MPG52_RS04750 (MPG52_04750) - 1013553..1014014 (+) 462 WP_245076249.1 hypothetical protein -
  MPG52_RS04755 (MPG52_04755) uvrC 1014015..1015799 (+) 1785 WP_245076251.1 excinuclease ABC subunit UvrC Machinery gene
  MPG52_RS04760 (MPG52_04760) - 1015810..1017075 (+) 1266 WP_120996447.1 homoserine dehydrogenase -
  MPG52_RS04765 (MPG52_04765) - 1017076..1017420 (+) 345 WP_001211708.1 YraN family protein -
  MPG52_RS04770 (MPG52_04770) trxA 1017509..1017829 (+) 321 WP_000020199.1 thioredoxin -
  MPG52_RS04775 (MPG52_04775) trxB 1017835..1018770 (+) 936 WP_120871976.1 thioredoxin-disulfide reductase -
  MPG52_RS04780 (MPG52_04780) - 1019143..1019964 (+) 822 WP_245076253.1 glycosyltransferase family 25 protein -
  MPG52_RS04785 (MPG52_04785) - 1020172..1020420 (-) 249 WP_000790557.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68554.76 Da        Isoelectric Point: 9.6734

>NTDB_id=667763 MPG52_RS04755 WP_245076251.1 1014015..1015799(+) (uvrC) [Helicobacter pylori strain Hpfe0021]
MADLLSSLKNLPNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSVRNNEITPNPRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCEDKITKEEYLKIAKECLEMIENKDRLIKELELKMEHLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGASNKAVLVKMFMRGGKIISSAFEKIHSLNGFDADEAMKQAIINHYQSHLPLIPEQILLN
ACSNEVLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFNLECVPYRVEIFDT
SHHSNSQCVGGMVVYENNAFQKNSYRRYHLKGSNEYAQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGTKDIIHTPSNTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=667763 MPG52_RS04755 WP_245076251.1 1014015..1015799(+) (uvrC) [Helicobacter pylori strain Hpfe0021]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTCCTAATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAAGCAAAAAACTTAAAAAAGCGCATCAAAAGCTATTTTTCTGTCCGCAATAATGAAATCACGCCTA
ATCCTCGTGCAAGCTTACGCATCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTGGAAAATTCTTTGATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGTGGGGCTAAGGATATTTTGGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATTAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGGATAAAATCACTAA
AGAAGAATATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAGGCTCATCAAAGAGCTTGAATTGA
AAATGGAGCACCTTTCTAACAACTTGCGTTTTGAAGAAGCCCTAATTTACAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCCTTCACTTGCATGGATTTGGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATGGCGCAAGCAATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTTAATGGGTTTGACG
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATACCAGAACAAATTCTATTAAAC
GCTTGCTCTAACGAAGTGCTTAAAGAATTGCAAGAGTTTATCTCTCATCAATATTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAGGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTTTTCAATTTAGAGTGCGTGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATTCAAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAACAATGCATTCCAAAAAAACTCTTACCGGCG
CTACCATTTAAAAGGCTCTAATGAATACGCTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTGCCAAAGAGC
CACCGCCTAATTTGTGGGTGATAGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAGGCTTATCGTTCTAAAGGGGGCACTAAAGACATTAT
CCATACGCCCAGCAATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCACAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGCATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATTTAA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(205-239)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

97.475

100

0.975

Multiple sequence alignment