Detailed information NTG0667719

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: OG705_RS20175
• Genome accession: NZ_CP108857
• Coordinates: 4570845..4573370 (+)
• Length: 841 a.a.
• NCBI ID: WP_164252176.1
• Uniprot ID: -
• Organism: Streptomyces sp. NBC_00838
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 4565845..4578370

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OG705_RS20145 (OG705_20155)	-	4567281..4567892 (+)	612	WP_405826689.1	hypothetical protein	-
OG705_RS20150 (OG705_20160)	-	4567906..4568085 (+)	180	WP_242573290.1	hypothetical protein	-
OG705_RS20155 (OG705_20165)	-	4568189..4568710 (+)	522	WP_242573300.1	BlaI/MecI/CopY family transcriptional regulator	-
OG705_RS20160 (OG705_20170)	-	4568720..4569253 (+)	534	WP_242573291.1	amino-acid N-acetyltransferase	-
OG705_RS20165 (OG705_20175)	-	4569398..4569733 (+)	336	WP_023539576.1	Lsr2 family protein	-
OG705_RS20170 (OG705_20180)	-	4569712..4570392 (-)	681	WP_242573292.1	SCO3374 family protein	-
OG705_RS20175 (OG705_20185)	clpC	4570845..4573370 (+)	2526	WP_164252176.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
OG705_RS20180 (OG705_20190)	-	4574027..4574695 (+)	669	WP_242573293.1	M23 family metallopeptidase	-
OG705_RS20185 (OG705_20195)	-	4574685..4575263 (-)	579	WP_242573294.1	TetR/AcrR family transcriptional regulator	-
OG705_RS20190 (OG705_20200)	-	4575389..4577014 (+)	1626	WP_405822189.1	MDR family MFS transporter	-
OG705_RS20195 (OG705_20205)	cseC	4577045..4578358 (-)	1314	WP_242573295.1	two-component system sensor histidine kinase CseC	-

Sequence

Protein

• Length: 841 a.a.
• Molecular weight: 93235.46 Da
• Isoelectric Point: 5.9188

>NTDB_id=667719 OG705_RS20175 WP_164252176.1 4570845..4573370(+) (clpC) [Streptomyces sp. NBC_00838]
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKALESLGISLEAVRQQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGADLNRVRQQVIQLLSGYQGKEAATAGGPAEGT
PSTSLVLDQFGRNLTQAARESKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVKGEVPETLKD
KHLYTLDLGALVAGSRYRGDFEERLKKVLKEIRTRGDIILFIDELHTLVGAGAAEGAIDAASILKPMLARGELQTIGATT
LDEYRKHLEKDAALERRFQPIQVAEPSLPHTIEILKGLRDRYEAHHRVSITDSALVAAATLADRYISDRFLPDKAIDLID
EAGSRMRIRRMTAPPDLREFDEKIANVRRDKESAIDSQDFEKAASLRDKEKQLLAAKTKREKEWKAGDMDVVAEVDEELI
AEVLATATGIPVFKLTEEESSRLLRMEDELHKRVIGQKDAIKALSQAIRRTRAGLKDPKRPGGSFIFAGPSGVGKTELSK
TLAEFLFGDEDALISLDMSEFSEKHTVSRLFGSPPGYVGYEEGGQLTEKVRRKPFSVVLFDEVEKAHPDIFNSLLQILED
GRLTDSQGRVVDFKNTVIIMTTNLGTRDISKGFNLGFAAQGDTKSNYERMKNKVNEELKQHFRPEFLNRVDDTVVFHQLT
EEDIIQIVDLMVTKVDERLKDRDMGLELSPNAKALLAKKGYDPVLGARPLRRTIQREIEDILSEKILFGELRPGHIVVVD
TEGEGEEKKFSFRGEEKSALPDVPPIEQAAGGAGPNLTKEA

Nucleotide

• Length: 2526 bp

>NTDB_id=667719 OG705_RS20175 WP_164252176.1 4570845..4573370(+) (clpC) [Streptomyces sp. NBC_00838]
ATGTTCGAGAGGTTCACCGACCGCGCGCGGCGGGTTGTCGTCCTGGCTCAGGAAGAAGCCCGGATGCTCAACCACAACTA
CATCGGCACCGAGCACATCCTCCTGGGCCTTATCCACGAGGGTGAGGGTGTCGCCGCTAAGGCCCTGGAGAGCCTCGGGA
TTTCGCTCGAGGCGGTCCGCCAGCAGGTGGAGGAGATCATCGGGCAGGGCCAGCAGGCTCCGTCCGGCCACATCCCCTTC
ACGCCCCGTGCCAAGAAGGTCCTGGAGCTGTCGCTCCGCGAGGCCCTTCAGCTCGGCCACAACTACATCGGCACCGAGCA
CATCCTGCTCGGCCTGATCCGCGAGGGCGAGGGCGTCGCGGCCCAGGTCCTCGTGAAGCTGGGCGCCGATCTCAACCGGG
TGCGGCAGCAGGTCATCCAGCTGCTCTCCGGTTACCAGGGCAAGGAGGCCGCCACCGCCGGCGGCCCGGCCGAGGGCACG
CCCTCGACCTCGCTCGTCCTGGACCAGTTCGGCAGGAATCTCACGCAGGCCGCCCGCGAATCCAAGCTCGACCCGGTCAT
CGGGCGCGAGAAGGAGATCGAGCGGGTCATGCAGGTGCTGTCCCGCCGTACGAAGAACAACCCGGTTCTCATCGGCGAGC
CCGGCGTCGGCAAGACGGCGGTCGTCGAGGGACTGGCGCAGGCCATCGTCAAGGGCGAGGTGCCCGAGACCCTCAAGGAC
AAGCACCTCTACACCCTGGACCTCGGCGCCCTGGTCGCGGGCTCCCGCTACCGAGGTGACTTCGAGGAGCGCCTGAAGAA
GGTCCTCAAGGAGATCCGCACCCGCGGCGACATCATCCTGTTCATCGACGAGCTCCACACCCTCGTGGGTGCGGGCGCCG
CCGAGGGCGCGATCGACGCGGCTTCGATCCTGAAGCCCATGCTCGCCCGTGGAGAGCTCCAGACCATCGGCGCCACGACG
CTCGACGAGTACCGCAAGCACCTGGAGAAGGACGCCGCGCTGGAGCGCCGCTTCCAGCCGATCCAGGTGGCCGAGCCGTC
GCTGCCGCACACCATCGAGATCCTCAAGGGTCTGCGGGACCGTTACGAGGCGCACCACCGCGTGTCCATCACGGACTCCG
CGCTGGTCGCAGCCGCGACGCTCGCCGACCGCTACATCTCGGACCGCTTCCTGCCGGACAAGGCGATCGACCTGATCGAC
GAGGCCGGCTCACGGATGCGCATCCGCCGGATGACCGCTCCGCCGGACCTCCGCGAGTTCGACGAGAAGATCGCGAACGT
CCGCCGCGACAAGGAGTCGGCCATCGACTCCCAGGACTTCGAGAAGGCAGCTTCGCTCCGCGACAAGGAGAAGCAGCTGC
TGGCCGCGAAGACCAAGCGGGAGAAGGAGTGGAAGGCCGGCGACATGGACGTCGTCGCCGAGGTGGACGAGGAGCTGATC
GCCGAGGTCCTGGCGACCGCCACGGGCATCCCGGTCTTCAAGCTCACCGAGGAGGAGTCCTCGCGGCTGCTCCGCATGGA
GGACGAGCTCCACAAGCGCGTCATCGGCCAGAAGGATGCCATCAAGGCGCTCTCCCAGGCGATCCGGCGTACGCGGGCGG
GTCTGAAGGACCCCAAGCGTCCCGGTGGCTCGTTCATCTTCGCCGGCCCCTCCGGAGTCGGTAAGACGGAGCTCTCCAAG
ACGCTCGCCGAATTCCTCTTCGGCGACGAGGACGCGCTGATCTCCCTCGACATGTCGGAGTTCAGCGAGAAGCACACGGT
CTCGCGTCTCTTCGGTTCTCCCCCCGGATACGTGGGGTACGAGGAGGGCGGCCAGCTCACCGAGAAGGTGCGCCGGAAGC
CGTTCTCCGTCGTCCTCTTCGACGAGGTCGAGAAGGCCCACCCCGATATCTTCAATTCCCTTCTGCAGATCCTGGAGGAC
GGTCGGCTGACCGACTCCCAGGGCCGGGTCGTGGACTTCAAGAACACGGTCATCATCATGACGACCAACCTCGGGACCAG
GGACATCTCCAAGGGGTTCAACCTGGGCTTCGCCGCCCAGGGCGACACCAAGTCCAACTACGAGCGGATGAAGAACAAGG
TCAACGAGGAGCTCAAGCAGCACTTCCGGCCCGAGTTCCTCAACCGTGTGGACGACACGGTCGTCTTCCACCAGCTCACC
GAGGAAGACATCATCCAGATCGTCGACCTCATGGTGACCAAGGTGGACGAGCGCCTGAAGGACCGGGACATGGGCCTGGA
GCTCAGCCCGAACGCCAAGGCGCTGCTCGCCAAGAAGGGTTACGACCCCGTTCTGGGCGCCCGGCCGCTGCGCCGGACGA
TCCAGCGCGAGATCGAGGACATCCTCTCCGAGAAGATCCTCTTCGGTGAGCTGCGCCCCGGTCACATCGTGGTCGTGGAC
ACCGAGGGTGAGGGCGAGGAGAAGAAGTTCAGCTTCCGCGGCGAGGAGAAGTCGGCGCTGCCCGACGTCCCGCCGATCGA
GCAGGCGGCCGGCGGTGCCGGTCCGAACCTGACGAAGGAGGCGTGA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (349-449)

• AAA domain (Cdc48 subfamily) (AAA_2) (541-712)

• ATPase family associated with various cellular activities (AAA) (AAA) (209-329)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (719-799)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (93-142)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (16-68)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	61.596	95.363	0.587
clpC	Streptococcus mutans UA159	44.819	98.692	0.442
clpC	Streptococcus thermophilus LMD-9	43.894	98.335	0.432
clpC	Streptococcus thermophilus LMG 18311	43.72	98.454	0.43
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	44.321	96.314	0.427
clpC	Streptococcus pneumoniae Rx1	44.458	95.482	0.424
clpC	Streptococcus pneumoniae D39	44.458	95.482	0.424
clpC	Streptococcus pneumoniae TIGR4	44.486	94.887	0.422
clpE	Streptococcus mutans UA159	53.674	74.435	0.4
clpE	Streptococcus pneumoniae Rx1	52.809	74.078	0.391
clpE	Streptococcus pneumoniae R6	52.809	74.078	0.391
clpE	Streptococcus pneumoniae D39	52.809	74.078	0.391
clpE	Streptococcus pneumoniae TIGR4	52.809	74.078	0.391
clpC	Lactococcus lactis subsp. cremoris KW2	52.581	73.722	0.388