Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   MPF98_RS04630 Genome accession   NZ_CP094153
Coordinates   974051..975835 (+) Length   594 a.a.
NCBI ID   WP_245048706.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe010     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 969051..980835
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPF98_RS04600 (MPF98_04600) motB 969715..970482 (+) 768 WP_001085307.1 flagellar motor protein MotB -
  MPF98_RS04605 (MPF98_04605) - 970486..970923 (+) 438 WP_001031792.1 hypothetical protein -
  MPF98_RS04610 (MPF98_04610) - 971102..972763 (+) 1662 WP_245048702.1 ABC transporter permease/substrate-binding protein -
  MPF98_RS04615 (MPF98_04615) - 972765..973406 (+) 642 WP_245048704.1 ATP-binding cassette domain-containing protein -
  MPF98_RS04620 (MPF98_04620) - 973418..973597 (-) 180 WP_180586319.1 hypothetical protein -
  MPF98_RS04625 (MPF98_04625) - 973589..974050 (+) 462 WP_033587181.1 hypothetical protein -
  MPF98_RS04630 (MPF98_04630) uvrC 974051..975835 (+) 1785 WP_245048706.1 excinuclease ABC subunit UvrC Machinery gene
  MPF98_RS04635 (MPF98_04635) - 975846..977111 (+) 1266 WP_180592443.1 homoserine dehydrogenase -
  MPF98_RS04640 (MPF98_04640) - 977112..977456 (+) 345 WP_180400925.1 YraN family protein -
  MPF98_RS04645 (MPF98_04645) trxA 977545..977865 (+) 321 WP_000020200.1 thioredoxin -
  MPF98_RS04650 (MPF98_04650) trxB 977871..978806 (+) 936 WP_245048708.1 thioredoxin-disulfide reductase -
  MPF98_RS04655 (MPF98_04655) - 978974..979795 (+) 822 WP_245048710.1 glycosyltransferase family 25 protein -
  MPF98_RS04660 (MPF98_04660) - 979992..980240 (-) 249 WP_212858334.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68820.11 Da        Isoelectric Point: 9.7098

>NTDB_id=667713 MPF98_RS04630 WP_245048706.1 974051..975835(+) (uvrC) [Helicobacter pylori strain Hpfe010]
MADLLSSLKNLSHSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNHRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQLGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGSNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQEFISHKYSKKIAISIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFQLECMPYRVEIFDA
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYTQMSELLTRRALDFNKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTANDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=667713 MPF98_RS04630 WP_245048706.1 974051..975835(+) (uvrC) [Helicobacter pylori strain Hpfe010]
ATGGCTGATTTATTATCCAGTTTGAAAAACCTTTCTCATAGCAGTGGCGTGTATCAATACTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCCATCCGTAATAATGAAATCACGCCCA
ATCATCGTGCAAGCTTACGAATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTAGAAAACGAACAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCTTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTGAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCTCTCATTTATAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATAGTGGGAGCAATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTCAACGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTAATGCCAGAACAAATCTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCTCATAAATACTCTAAAAAAATCGCTATTAGTATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTCTTTCAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGATGCA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTAATAAAGAGC
CGCCGCCTAATTTGTGGGTAATCGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATTGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGTGCTAAAGACATCAT
CCACACCGCTAACGATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATTTAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.801

100

0.968

Multiple sequence alignment