Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   MPG09_RS04630 Genome accession   NZ_CP094150
Coordinates   988774..990558 (+) Length   594 a.a.
NCBI ID   WP_245026405.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe022     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 983774..995558
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG09_RS04600 (MPG09_04600) motB 984435..985202 (+) 768 WP_001085319.1 flagellar motor protein MotB -
  MPG09_RS04605 (MPG09_04605) - 985206..985643 (+) 438 WP_001031792.1 hypothetical protein -
  MPG09_RS04610 (MPG09_04610) - 985823..987484 (+) 1662 WP_245026399.1 ABC transporter permease/substrate-binding protein -
  MPG09_RS04615 (MPG09_04615) - 987488..988129 (+) 642 WP_245026401.1 ATP-binding cassette domain-containing protein -
  MPG09_RS04620 (MPG09_04620) - 988141..988320 (-) 180 WP_171930372.1 hypothetical protein -
  MPG09_RS04625 (MPG09_04625) - 988312..988773 (+) 462 WP_245026403.1 hypothetical protein -
  MPG09_RS04630 (MPG09_04630) uvrC 988774..990558 (+) 1785 WP_245026405.1 excinuclease ABC subunit UvrC Machinery gene
  MPG09_RS04635 (MPG09_04635) - 990569..991834 (+) 1266 WP_245026407.1 homoserine dehydrogenase -
  MPG09_RS04640 (MPG09_04640) - 991835..992179 (+) 345 WP_001211650.1 YraN family protein -
  MPG09_RS04645 (MPG09_04645) trxA 992268..992588 (+) 321 WP_000020200.1 thioredoxin -
  MPG09_RS04650 (MPG09_04650) trxB 992594..993529 (+) 936 WP_220939135.1 thioredoxin-disulfide reductase -
  MPG09_RS04655 (MPG09_04655) - 993689..994510 (+) 822 WP_021306422.1 glycosyltransferase family 25 protein -
  MPG09_RS04660 (MPG09_04660) - 994715..994963 (-) 249 WP_000790557.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68800.21 Da        Isoelectric Point: 9.7098

>NTDB_id=667666 MPG09_RS04630 WP_245026405.1 988774..990558(+) (uvrC) [Helicobacter pylori strain Hpfe022]
MADLLSSLKNLSHSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNHRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYEVLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGSNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQDFISHQYSKKIALIIPKKGDKLALIEIAMKNAQEIFSQEKISNEDLILEEARSLFKLECMPYRVEIFDV
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYTQMSELLTRRALDFAKEPPPNLWVIDGGRVQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTASDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=667666 MPG09_RS04630 WP_245026405.1 988774..990558(+) (uvrC) [Helicobacter pylori strain Hpfe022]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCTATCCGTAATAATGAAATCACGCCCA
ATCATCGTGCAAGCTTACGCATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAACCCAAATACAACATCCTTTTAAGAGACGATAAAACTTA
CCCCTATATTTATATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTAGACAGCTTGTATGAAGTACTCCCATTAGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCTCTCATTTATAGGGATAGGATTGCAAAAATCCAAAAAATC
GCCCCCTTTACTTGTATGGATTTGGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATAGTGGGAGCAATAAGGCAGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTCAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCTATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCTGAACAGATTTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGATTTTATCTCTCATCAATATTCTAAAAAAATCGCTCTTATCATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAATCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTCTTTAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGATGTA
AGCCACCATGCCAACAGCCAATGCGTGGGAGGAATGGTCGTGTATGAAAACCATGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTGCCAAAGAGC
CGCCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGTGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCCAAAGGAGGCGCTAAAGACATTAT
CCACACCGCTAGCGATACTTTTAAATTACTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGCATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCTGTTTTAAAAAAACGAATTTAA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(205-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.97

100

0.97

Multiple sequence alignment