Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/comE3   Type   Machinery gene
Locus tag   MPF84_RS07085 Genome accession   NZ_CP094149
Coordinates   1477454..1478767 (-) Length   437 a.a.
NCBI ID   WP_245085635.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe023     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1477454..1490294 1477454..1478767 within 0


Gene organization within MGE regions


Location: 1477454..1490294
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPF84_RS07085 (MPF84_07085) comEC/comE3 1477454..1478767 (-) 1314 WP_245085635.1 ComEC/Rec2 family competence protein Machinery gene
  MPF84_RS07090 (MPF84_07090) - 1478764..1480230 (-) 1467 WP_245085637.1 replicative DNA helicase -
  MPF84_RS07095 (MPF84_07095) - 1480241..1481635 (-) 1395 WP_245085639.1 NAD(P)H-hydrate dehydratase -
  MPF84_RS07100 (MPF84_07100) crdS 1481638..1482840 (-) 1203 WP_245086814.1 copper-sensing histidine kinase CrdS -
  MPF84_RS07105 (MPF84_07105) crdR 1482806..1483447 (-) 642 WP_154417806.1 copper response regulator transcription factor CrdR -
  MPF84_RS07110 (MPF84_07110) - 1483535..1484806 (-) 1272 WP_245085641.1 restriction endonuclease subunit R -
  MPF84_RS07115 (MPF84_07115) - 1484822..1485604 (-) 783 WP_039704080.1 site-specific DNA-methyltransferase -
  MPF84_RS07120 (MPF84_07120) - 1485591..1486454 (-) 864 WP_120933440.1 site-specific DNA-methyltransferase -
  MPF84_RS07125 (MPF84_07125) - 1486599..1486961 (+) 363 WP_280636978.1 type II restriction endonuclease -
  MPF84_RS07130 (MPF84_07130) - 1486958..1487851 (+) 894 WP_245085643.1 Dam family site-specific DNA-(adenine-N6)-methyltransferase -
  MPF84_RS07135 (MPF84_07135) - 1487823..1490294 (+) 2472 Protein_1401 site-specific DNA-methyltransferase -

Sequence

Protein


Download         Length: 437 a.a.        Molecular weight: 50052.05 Da        Isoelectric Point: 9.8315

>NTDB_id=667648 MPF84_RS07085 WP_245085635.1 1477454..1478767(-) (comEC/comE3) [Helicobacter pylori strain Hpfe023]
MKDKTFQGAFELLATPKEYLLCGVILSLLLALNLYLEYLNYQKLDFSKPTSLNAQILLQYPKTKDQKTYFVLKLQSKGMI
FYATIKEPLKNLQYRYAQFFGKIKPCSFLESLKSCFFQTYSFSLTRKQDFKSHWRHFIDSAHSSALVGNLYRALFIGDSL
NKDLRDRANALGINHLLAISGFHLGILSASMYFLFSLFYTPLQKRYFPYRNAFYDIGVLVWVFLLGYLLLLDFLPSFFRA
FLMGLLGFLACFFGVRLLSFKLLILACCIAIALLPKLLFSVGFLLSVCGVWYIFLFLKHTQAFFKTSSFLARSFQVISLS
ALVFLNMLIIAHAFFPMFSPYQLFSIPLGLIFVVFFPLSLFLHAVGLGSLLDGILNMPLMIPTISISSPLWLLGAHLFLT
ILSVRFFKVYLSMNVLSAGFFLYCCYQYIIMPSLIVG

Nucleotide


Download         Length: 1314 bp        

>NTDB_id=667648 MPF84_RS07085 WP_245085635.1 1477454..1478767(-) (comEC/comE3) [Helicobacter pylori strain Hpfe023]
TTGAAAGATAAAACTTTTCAGGGGGCGTTTGAACTTCTTGCAACCCCCAAAGAATACTTGTTGTGTGGGGTTATTTTAAG
CCTTTTGTTAGCACTTAATCTTTATTTAGAATACTTGAATTACCAAAAGCTTGATTTTTCAAAACCTACAAGTCTGAACG
CTCAAATCTTGTTGCAATACCCTAAAACTAAAGATCAAAAAACCTATTTTGTTTTAAAGCTCCAATCAAAGGGCATGATC
TTTTATGCCACCATTAAAGAGCCTTTAAAAAACCTCCAATACCGCTACGCGCAATTTTTTGGCAAAATCAAACCTTGCTC
GTTTTTGGAGTCTTTAAAATCATGCTTTTTTCAAACTTATTCTTTTTCTTTAACACGAAAACAAGATTTTAAATCGCATT
GGCGCCATTTCATTGACAGCGCTCATTCAAGCGCTTTAGTGGGGAATTTGTATCGAGCGTTGTTTATAGGGGATAGCTTG
AATAAAGACTTAAGAGATAGGGCTAACGCATTAGGGATCAACCACTTACTAGCCATTAGCGGATTCCATTTAGGGATTTT
GAGTGCGAGTATGTATTTCCTTTTCTCTCTTTTTTATACCCCCTTACAAAAACGCTATTTCCCTTATAGGAACGCTTTTT
ATGATATAGGGGTTTTGGTGTGGGTTTTTTTGCTAGGGTATTTATTGCTATTAGATTTTTTACCCTCTTTTTTCAGGGCG
TTTTTAATGGGCTTGTTAGGGTTTTTGGCATGTTTTTTTGGGGTAAGGCTTTTGAGTTTTAAACTTTTGATTTTAGCGTG
CTGTATCGCTATAGCGTTACTCCCTAAATTGCTTTTTAGCGTGGGGTTTTTGCTTTCTGTTTGTGGGGTGTGGTATATCT
TTTTGTTTTTAAAACACACTCAAGCCTTTTTTAAAACCTCTTCTTTTTTGGCGCGATCTTTTCAGGTCATAAGCTTAAGC
GCGCTAGTGTTTTTGAACATGCTCATCATTGCGCATGCCTTTTTCCCTATGTTTTCGCCCTACCAACTCTTTAGCATTCC
TTTAGGCTTGATTTTTGTCGTGTTTTTCCCTTTGAGTTTGTTTTTGCATGCTGTGGGTTTGGGGTCTTTGCTGGATGGTA
TTTTAAACATGCCTTTAATGATCCCTACGATTTCAATCTCTTCGCCTTTATGGCTTTTGGGGGCGCATTTATTTTTAACG
ATTCTAAGTGTGCGTTTTTTTAAAGTTTATTTAAGCATGAATGTTTTAAGCGCGGGCTTTTTCTTGTATTGTTGCTATCA
ATATATTATAATGCCTAGTTTAATTGTAGGTTAG

Domains

Predicted by InterproScan.

Competence protein (Competence)

(159-406)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/comE3 Helicobacter pylori 26695

94.05

100

0.941

Multiple sequence alignment