Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   OHA79_RS31360 Genome accession   NZ_CP108853
Coordinates   6842483..6843142 (+) Length   219 a.a.
NCBI ID   WP_266981390.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00841     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 6837483..6848142
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHA79_RS31350 (OHA79_31340) - 6839450..6841696 (+) 2247 WP_266981394.1 serine/threonine-protein kinase -
  OHA79_RS31355 (OHA79_31345) - 6841730..6842362 (-) 633 WP_266981392.1 PepSY domain-containing protein -
  OHA79_RS31360 (OHA79_31350) ciaR 6842483..6843142 (+) 660 WP_266981390.1 response regulator transcription factor Regulator
  OHA79_RS31365 (OHA79_31355) - 6843139..6844623 (+) 1485 WP_266981388.1 HAMP domain-containing sensor histidine kinase -
  OHA79_RS31370 (OHA79_31360) - 6844700..6845176 (-) 477 WP_266981386.1 MarR family transcriptional regulator -
  OHA79_RS31375 (OHA79_31365) - 6845327..6846094 (-) 768 WP_266981384.1 AIM24 family protein -
  OHA79_RS31380 (OHA79_31370) - 6846091..6846741 (-) 651 WP_037689354.1 AIM24 family protein -
  OHA79_RS31385 (OHA79_31375) - 6846741..6847373 (-) 633 WP_266990470.1 AIM24 family protein -
  OHA79_RS31390 (OHA79_31380) - 6847585..6847935 (+) 351 WP_266981381.1 DUF3817 domain-containing protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 23766.41 Da        Isoelectric Point: 4.9817

>NTDB_id=667644 OHA79_RS31360 WP_266981390.1 6842483..6843142(+) (ciaR) [Streptomyces sp. NBC_00841]
MRLLIVEDERRLAMSLAGGLTAEGFAVDVVHDGLEGLHRASEGVYDLVILDIMLPGMNGYRVCAALRAAGHEVPILMLTA
KDGEYDEAEGLDTGADDYLTKPFSYVVLVARIRALLRRRGGSASPVITVGALRMDTAARRVLLGEDEVTLTAKEFAVLEQ
LALRVGQVVSKADILEHVWDFAYDGDPNIVEVYVSALRRKLGAASIRTVRGAGYRLEAL

Nucleotide


Download         Length: 660 bp        

>NTDB_id=667644 OHA79_RS31360 WP_266981390.1 6842483..6843142(+) (ciaR) [Streptomyces sp. NBC_00841]
ATGCGCCTGTTGATCGTGGAGGACGAGAGACGGCTGGCGATGTCCCTGGCCGGGGGACTCACCGCCGAGGGCTTCGCCGT
GGATGTCGTGCATGACGGCCTCGAAGGACTGCACCGCGCGAGCGAGGGGGTGTACGACCTCGTGATCCTCGACATCATGC
TGCCCGGGATGAACGGCTACCGGGTCTGCGCCGCCCTGCGCGCCGCCGGTCACGAGGTGCCGATCCTGATGCTGACGGCG
AAGGACGGGGAGTACGACGAGGCGGAGGGGCTCGATACCGGCGCCGACGACTATCTGACCAAGCCGTTCTCGTACGTGGT
GCTGGTCGCCCGGATCCGGGCGCTGCTGCGACGCCGCGGCGGTTCCGCCTCGCCCGTGATCACCGTCGGCGCGCTGCGGA
TGGACACCGCCGCCCGCCGCGTTCTTCTCGGCGAGGACGAAGTCACGCTCACGGCCAAGGAGTTCGCCGTGCTGGAGCAG
CTGGCTCTGCGGGTGGGCCAGGTGGTGAGCAAGGCGGACATCCTGGAACACGTCTGGGACTTCGCGTACGACGGGGACCC
GAACATCGTCGAGGTGTACGTCAGCGCACTGCGCCGCAAGCTCGGCGCGGCGTCCATCCGTACGGTGCGGGGCGCAGGCT
ACCGGCTGGAGGCGCTGTGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-216)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

41.441

100

0.42
  vicR Streptococcus mutans UA159

39.224

100

0.416
  micA Streptococcus pneumoniae Cp1015

38.428

100

0.402
  ciaR Streptococcus pneumoniae R6

39.189

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

39.189

100

0.397
  ciaR Streptococcus pneumoniae D39

39.189

100

0.397
  ciaR Streptococcus pneumoniae Rx1

39.189

100

0.397
  covR Streptococcus salivarius strain HSISS4

38.739

100

0.393
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.462

100

0.388

Multiple sequence alignment