Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   MPG27_RS04540 Genome accession   NZ_CP094147
Coordinates   959409..961193 (+) Length   594 a.a.
NCBI ID   WP_245041541.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe027     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 954409..966193
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG27_RS04510 (MPG27_04510) motB 955070..955837 (+) 768 WP_001085311.1 flagellar motor protein MotB -
  MPG27_RS04515 (MPG27_04515) - 955841..956278 (+) 438 WP_001031792.1 hypothetical protein -
  MPG27_RS04520 (MPG27_04520) - 956458..958119 (+) 1662 WP_245041538.1 ABC transporter permease/substrate-binding protein -
  MPG27_RS04525 (MPG27_04525) - 958123..958764 (+) 642 WP_245041539.1 ATP-binding cassette domain-containing protein -
  MPG27_RS04530 (MPG27_04530) - 958776..958955 (-) 180 WP_000468796.1 hypothetical protein -
  MPG27_RS04535 (MPG27_04535) - 958947..959408 (+) 462 WP_245041540.1 hypothetical protein -
  MPG27_RS04540 (MPG27_04540) uvrC 959409..961193 (+) 1785 WP_245041541.1 excinuclease ABC subunit UvrC Machinery gene
  MPG27_RS04545 (MPG27_04545) - 961204..962469 (+) 1266 WP_000746791.1 homoserine dehydrogenase -
  MPG27_RS04550 (MPG27_04550) - 962470..962814 (+) 345 WP_231168136.1 YraN family protein -
  MPG27_RS04555 (MPG27_04555) trxA 962903..963223 (+) 321 WP_000020200.1 thioredoxin -
  MPG27_RS04560 (MPG27_04560) trxB 963229..964164 (+) 936 WP_245041542.1 thioredoxin-disulfide reductase -
  MPG27_RS04565 (MPG27_04565) - 964331..965152 (+) 822 WP_245041543.1 glycosyltransferase family 25 protein -
  MPG27_RS04570 (MPG27_04570) - 965359..965607 (-) 249 WP_033589505.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68770.10 Da        Isoelectric Point: 9.7879

>NTDB_id=667597 MPG27_RS04540 WP_245041541.1 959409..961193(+) (uvrC) [Helicobacter pylori strain Hpfe027]
MADLLSSLKNLSHSSGVYQYFDKNRQLLYIGKAKNLKKRIRSYFSVRNNEITPNHRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGSHKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQEFISHKYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFKLECMPYRVEIFDT
SHHANSQCVGGMVVYENHAFQKNSYRRYHLKGSNEYTQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTANDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=667597 MPG27_RS04540 WP_245041541.1 959409..961193(+) (uvrC) [Helicobacter pylori strain Hpfe027]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAGAAGCTATTTTTCTGTCCGCAATAATGAAATCACGCCCA
ATCATCGCGCAAGCTTACGCATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAACCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACCGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAAGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTGAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTTATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATAGTGGGAGCCATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTTAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTAATGCCAGAACAGATTTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCTCATAAATACTCTAAAAAAATCGCTCTTAGTATTCC
TAAAAAAGGCGATAAACTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTCTTTAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGCATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTGCCAAAGAGC
CACCGCCTAATTTATGGGTGATCGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGAGGCGCTAAAGACATTAT
CCACACCGCTAACGATACTTTTAAATTGCTCCCTAGCGACAAGCGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAAGGCATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATTTAA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(205-239)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

97.306

100

0.973

Multiple sequence alignment