Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/comE3   Type   Machinery gene
Locus tag   MPG75_RS06900 Genome accession   NZ_CP094144
Coordinates   1436216..1437529 (-) Length   437 a.a.
NCBI ID   WP_245039203.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe029     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1400399..1448534 1436216..1437529 within 0


Gene organization within MGE regions


Location: 1400399..1448534
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG75_RS06710 (MPG75_06710) prfA 1400399..1401457 (-) 1059 WP_245039170.1 peptide chain release factor 1 -
  MPG75_RS06715 (MPG75_06715) rpsT 1401571..1401840 (-) 270 WP_001273632.1 30S ribosomal protein S20 -
  MPG75_RS06720 (MPG75_06720) glmM 1401930..1403267 (+) 1338 WP_000688362.1 phosphoglucosamine mutase -
  MPG75_RS06725 (MPG75_06725) lspA 1403261..1403734 (+) 474 WP_245039172.1 signal peptidase II -
  MPG75_RS06735 (MPG75_06735) ureA 1404114..1404830 (+) 717 WP_000779229.1 urease subunit alpha -
  MPG75_RS06740 (MPG75_06740) ureB 1404834..1406543 (+) 1710 WP_000724309.1 urease subunit beta -
  MPG75_RS06745 (MPG75_06745) ureI 1406735..1407322 (+) 588 WP_000901257.1 acid-activated urea channel protein UreI -
  MPG75_RS06750 (MPG75_06750) ureE 1407324..1407836 (+) 513 WP_245039174.1 urease accessory protein UreE -
  MPG75_RS06755 (MPG75_06755) - 1407848..1408618 (+) 771 WP_245039176.1 urease accessory protein UreF -
  MPG75_RS06760 (MPG75_06760) ureG 1408647..1409246 (+) 600 WP_000238747.1 urease accessory protein UreG -
  MPG75_RS06765 (MPG75_06765) - 1409246..1410043 (+) 798 WP_245039178.1 urease accessory protein UreD -
  MPG75_RS06770 (MPG75_06770) - 1410115..1411596 (-) 1482 Protein_1318 hypothetical protein -
  MPG75_RS06775 (MPG75_06775) - 1411608..1412412 (-) 805 Protein_1319 hypothetical protein -
  MPG75_RS06780 (MPG75_06780) - 1412414..1413125 (-) 712 Protein_1320 M protein -
  MPG75_RS06785 (MPG75_06785) - 1413591..1413800 (-) 210 WP_000849012.1 hypothetical protein -
  MPG75_RS06790 (MPG75_06790) - 1414118..1417675 (+) 3558 WP_245039180.1 bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase -
  MPG75_RS06795 (MPG75_06795) putP 1417702..1419201 (+) 1500 WP_245039182.1 sodium/proline symporter PutP -
  MPG75_RS06800 (MPG75_06800) - 1419230..1420120 (+) 891 Protein_1324 DNA cytosine methyltransferase -
  MPG75_RS06805 (MPG75_06805) - 1420117..1420815 (+) 699 WP_245039184.1 site-specific DNA-methyltransferase -
  MPG75_RS06810 (MPG75_06810) - 1420867..1420938 (+) 72 Protein_1326 agmatine deiminase -
  MPG75_RS06815 (MPG75_06815) - 1421115..1421843 (-) 729 WP_245039186.1 TerC family protein -
  MPG75_RS06820 (MPG75_06820) corA 1421850..1422812 (-) 963 WP_245028342.1 magnesium/cobalt transporter CorA -
  MPG75_RS06825 (MPG75_06825) - 1422828..1424036 (-) 1209 WP_245039188.1 phosphoglycerate kinase -
  MPG75_RS06830 (MPG75_06830) gap 1424052..1425044 (-) 993 WP_245039190.1 type I glyceraldehyde-3-phosphate dehydrogenase -
  MPG75_RS06835 (MPG75_06835) ung 1425133..1425834 (-) 702 WP_245039192.1 uracil-DNA glycosylase -
  MPG75_RS06840 (MPG75_06840) - 1425855..1426562 (-) 708 WP_220846675.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  MPG75_RS06845 (MPG75_06845) - 1426549..1427724 (-) 1176 WP_245039194.1 SH3 domain-containing protein -
  MPG75_RS06850 (MPG75_06850) - 1427731..1429095 (-) 1365 WP_245039196.1 S41 family peptidase -
  MPG75_RS06855 (MPG75_06855) - 1429206..1429478 (-) 273 Protein_1335 adenine specific DNA methyltransferase 2 domain protein -
  MPG75_RS06860 (MPG75_06860) - 1429504..1430397 (-) 894 WP_245039198.1 HpyAIV family type II restriction enzyme -
  MPG75_RS06865 (MPG75_06865) - 1430397..1431476 (-) 1080 WP_000346767.1 site-specific DNA-methyltransferase -
  MPG75_RS06870 (MPG75_06870) nadC 1431679..1432500 (-) 822 WP_245039199.1 carboxylating nicotinate-nucleotide diphosphorylase -
  MPG75_RS06875 (MPG75_06875) nadA 1432500..1433510 (-) 1011 WP_245039200.1 quinolinate synthase NadA -
  MPG75_RS06880 (MPG75_06880) - 1433500..1434303 (-) 804 WP_245039201.1 phosphatidylserine decarboxylase -
  MPG75_RS06885 (MPG75_06885) - 1434300..1434803 (-) 504 WP_120910561.1 helix-turn-helix domain-containing protein -
  MPG75_RS06890 (MPG75_06890) - 1434816..1435310 (-) 495 WP_014537179.1 hypothetical protein -
  MPG75_RS06895 (MPG75_06895) mqnP 1435303..1436145 (-) 843 WP_232255053.1 menaquinone biosynthesis prenyltransferase MqnP -
  MPG75_RS06900 (MPG75_06900) comEC/comE3 1436216..1437529 (-) 1314 WP_245039203.1 ComEC/Rec2 family competence protein Machinery gene
  MPG75_RS06905 (MPG75_06905) - 1437526..1438986 (-) 1461 WP_245039205.1 replicative DNA helicase -
  MPG75_RS06910 (MPG75_06910) - 1438997..1440391 (-) 1395 WP_245039207.1 NAD(P)H-hydrate dehydratase -
  MPG75_RS06915 (MPG75_06915) crdS 1440394..1441596 (-) 1203 WP_245040133.1 copper-sensing histidine kinase CrdS -
  MPG75_RS06920 (MPG75_06920) crdR 1441562..1442203 (-) 642 WP_245039209.1 copper response regulator transcription factor CrdR -
  MPG75_RS06925 (MPG75_06925) - 1442288..1443559 (-) 1272 Protein_1349 restriction endonuclease subunit R -
  MPG75_RS06930 (MPG75_06930) - 1443575..1444357 (-) 783 WP_245039211.1 site-specific DNA-methyltransferase -
  MPG75_RS06935 (MPG75_06935) - 1444344..1445207 (-) 864 Protein_1351 site-specific DNA-methyltransferase -
  MPG75_RS06940 (MPG75_06940) - 1445352..1445711 (+) 360 WP_280636864.1 type II restriction endonuclease -
  MPG75_RS06945 (MPG75_06945) - 1445714..1446589 (+) 876 WP_245039215.1 Dam family site-specific DNA-(adenine-N6)-methyltransferase -

Sequence

Protein


Download         Length: 437 a.a.        Molecular weight: 50088.02 Da        Isoelectric Point: 9.8515

>NTDB_id=667561 MPG75_RS06900 WP_245039203.1 1436216..1437529(-) (comEC/comE3) [Helicobacter pylori strain Hpfe029]
MKDKTFQGAFELLTTPKEYLLCGVILSLLLVLNLYLEYLNYQKLDFSKPTSLNAQILLQYPKTKDQKTYFVLKLQSKGMI
FYTTIKEPLKNLQYRHAQFFGKIKPCSFLESLKSCFFQTYSFSLTRKQDFKSHWRHFIDSAHSSALVGNLYRALFIGDSL
NKDLRDRANALGINHLLAISGFHLGILSASVYFLFSLFYTPLQKRYFPYRNAFYDIGVLVWVFLLGYLLLLDFLPSFFRA
FLMGLLGFLACFFGVRLLSFKLLILACCIAIALLPKLLFSVGFLLSVCGVWYIFLFLKHTQAFFKTSSFLARSFQVISLS
ALVFLNMLIIAHAFFPMFSPYQLFSIPLGLIFIVFFPLSLFLHAVGLGSLLDGILNMPLMIPTISVFSPLWLLGAHLFLT
ILSARFFKVYLSMNVLSAGFFLYCCYQYIIMPSSIVG

Nucleotide


Download         Length: 1314 bp        

>NTDB_id=667561 MPG75_RS06900 WP_245039203.1 1436216..1437529(-) (comEC/comE3) [Helicobacter pylori strain Hpfe029]
TTGAAAGATAAAACTTTTCAGGGGGCGTTTGAACTTCTTACAACCCCCAAAGAATATTTGTTGTGTGGGGTTATTTTAAG
CCTTTTGTTGGTGCTTAATCTTTATTTAGAATATTTGAATTACCAAAAGCTTGATTTTTCAAAACCTACAAGCCTGAACG
CTCAAATCTTGTTGCAATACCCTAAAACTAAAGATCAAAAAACCTATTTTGTTTTAAAGCTCCAGTCAAAGGGCATGATC
TTTTACACTACCATTAAAGAGCCTTTAAAAAACCTCCAATACCGCCATGCGCAATTTTTTGGCAAAATCAAACCTTGCTC
ATTTTTAGAGTCTCTAAAATCATGCTTTTTTCAAACTTATTCTTTTTCTTTAACACGAAAACAAGATTTCAAATCGCATT
GGCGCCATTTCATTGACAGCGCTCATTCAAGCGCTTTAGTGGGTAATTTGTATCGAGCGTTGTTTATAGGGGATAGCTTG
AATAAAGATTTAAGAGATAGGGCTAACGCGCTAGGGATCAACCACTTACTGGCCATTAGCGGGTTTCATTTAGGGATTTT
GAGCGCGAGCGTGTATTTTCTTTTCTCTCTTTTTTATACCCCCTTACAAAAACGCTATTTCCCTTATAGGAACGCTTTTT
ATGATATAGGGGTTTTGGTGTGGGTTTTTTTGCTAGGGTATTTATTGCTATTAGATTTTTTACCCTCTTTTTTCAGGGCG
TTTTTAATGGGCTTGTTAGGGTTTTTGGCATGCTTTTTTGGGGTAAGGCTTTTGAGTTTTAAACTTTTGATTTTAGCGTG
CTGTATCGCTATAGCGTTACTCCCTAAATTGCTTTTTAGCGTGGGGTTTTTGCTTTCTGTTTGTGGGGTGTGGTATATCT
TTTTATTTTTAAAACACACTCAAGCCTTTTTTAAAACCTCTTCTTTTTTGGCGCGATCTTTTCAGGTCATAAGCTTAAGC
GCGCTAGTGTTTTTGAACATGCTCATTATTGCGCATGCCTTTTTCCCTATGTTTTCGCCCTACCAACTCTTTAGCATTCC
TTTAGGCTTGATTTTTATCGTGTTTTTCCCTTTGAGTTTGTTCTTGCATGCTGTGGGTTTGGGGTCTTTGCTGGATGGTA
TTTTAAACATGCCTTTAATGATTCCTACGATTTCGGTTTTTTCGCCTTTATGGCTTTTGGGGGCGCATTTATTTTTAACG
ATTCTAAGCGCGCGTTTTTTTAAAGTTTATTTAAGCATGAATGTTTTAAGCGCGGGCTTTTTCTTGTATTGTTGCTATCA
ATATATTATAATGCCTAGTTCAATTGTAGGTTAG

Domains

Predicted by InterproScan.

Competence protein (Competence)

(159-390)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/comE3 Helicobacter pylori 26695

95.195

100

0.952

Multiple sequence alignment