Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   MPG75_RS03190 Genome accession   NZ_CP094144
Coordinates   658807..660591 (-) Length   594 a.a.
NCBI ID   WP_245039902.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe029     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 653807..665591
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG75_RS03160 (MPG75_03160) - 654407..654655 (+) 249 WP_000790557.1 RNA-binding protein -
  MPG75_RS03165 (MPG75_03165) - 654848..655669 (-) 822 WP_245039898.1 glycosyltransferase family 25 protein -
  MPG75_RS03170 (MPG75_03170) trxB 655836..656771 (-) 936 WP_180394471.1 thioredoxin-disulfide reductase -
  MPG75_RS03175 (MPG75_03175) trxA 656777..657097 (-) 321 WP_000020199.1 thioredoxin -
  MPG75_RS03180 (MPG75_03180) - 657186..657530 (-) 345 WP_001211650.1 YraN family protein -
  MPG75_RS03185 (MPG75_03185) - 657531..658796 (-) 1266 WP_245039900.1 homoserine dehydrogenase -
  MPG75_RS03190 (MPG75_03190) uvrC 658807..660591 (-) 1785 WP_245039902.1 excinuclease ABC subunit UvrC Machinery gene
  MPG75_RS03195 (MPG75_03195) - 660592..661053 (-) 462 WP_000437191.1 hypothetical protein -
  MPG75_RS03200 (MPG75_03200) - 661045..661224 (+) 180 WP_000468796.1 hypothetical protein -
  MPG75_RS03205 (MPG75_03205) - 661236..661877 (-) 642 WP_245039904.1 ATP-binding cassette domain-containing protein -
  MPG75_RS03210 (MPG75_03210) - 661879..663540 (-) 1662 WP_245039906.1 ABC transporter permease/substrate-binding protein -
  MPG75_RS03215 (MPG75_03215) - 663723..664160 (-) 438 WP_001031792.1 hypothetical protein -
  MPG75_RS03220 (MPG75_03220) motB 664164..664931 (-) 768 WP_001085329.1 flagellar motor protein MotB -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68818.16 Da        Isoelectric Point: 9.8211

>NTDB_id=667553 MPG75_RS03190 WP_245039902.1 658807..660591(-) (uvrC) [Helicobacter pylori strain Hpfe029]
MADLLSSLKNLSHSSGVYQYFDKNRQLLYIGKAKNLKKRIRSYFSIHNNEITPNHRTSLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKKCLEMIENKDKLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGSNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQDFISHKYSKKIALSIPKKGDKLALIGIAMKNAQEIFSQEKTSNEDLILEEARSLFKLECMPYRVEIFDT
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYTQMSELLTRRALDFNKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTANDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASMKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=667553 MPG75_RS03190 WP_245039902.1 658807..660591(-) (uvrC) [Helicobacter pylori strain Hpfe029]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAGAAGCTATTTTTCTATCCACAATAATGAAATCACGCCTA
ACCATCGCACCAGCTTACGAATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAACAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAACCCAAATACAACATTCTTTTAAGAGATGATAAAACTTA
CCCCTATATTTATATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCATTAGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTGAAAATCGCTAAAAAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTACGATTTGGATATTTTTGCTTTTTATAGTGGGAGCAATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTCAACGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTAATGCCAGAACAAATCTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGATTTTATCTCTCATAAATACTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGGAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTCTTTAAATTAGAGTGTATGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCACGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAACGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTAATAAAGAGC
CGCCGCCTAATTTGTGGGTGATCGATGGAGGGAGAGCACAATTAAACATCGCTTTAGAAATTTTAAAAAGTAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATCAT
CCACACCGCTAACGATACTTTTAAATTGCTCCCTAGCGACAAGCGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGCATA
GGAGAAGCCAGCATGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCTGTTTTAAAAAAACGGATTTAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.296

100

0.963

Multiple sequence alignment