Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   MPG53_RS03130 Genome accession   NZ_CP094139
Coordinates   644853..646637 (-) Length   594 a.a.
NCBI ID   WP_245061094.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe036     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 639853..651637
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG53_RS03100 (MPG53_03100) - 640438..640686 (+) 249 WP_000790564.1 RNA-binding protein -
  MPG53_RS03105 (MPG53_03105) - 640888..641715 (-) 828 WP_245061090.1 glycosyltransferase family 25 protein -
  MPG53_RS03110 (MPG53_03110) trxB 641882..642817 (-) 936 WP_245061092.1 thioredoxin-disulfide reductase -
  MPG53_RS03115 (MPG53_03115) trxA 642823..643143 (-) 321 WP_000020200.1 thioredoxin -
  MPG53_RS03120 (MPG53_03120) - 643232..643576 (-) 345 WP_001211650.1 YraN family protein -
  MPG53_RS03125 (MPG53_03125) - 643577..644842 (-) 1266 WP_154443338.1 homoserine dehydrogenase -
  MPG53_RS03130 (MPG53_03130) uvrC 644853..646637 (-) 1785 WP_245061094.1 excinuclease ABC subunit UvrC Machinery gene
  MPG53_RS03135 (MPG53_03135) - 646638..647099 (-) 462 WP_000437188.1 hypothetical protein -
  MPG53_RS03140 (MPG53_03140) - 647091..647270 (+) 180 WP_000468796.1 hypothetical protein -
  MPG53_RS03145 (MPG53_03145) - 647282..647923 (-) 642 WP_245061096.1 ATP-binding cassette domain-containing protein -
  MPG53_RS03150 (MPG53_03150) - 647925..649586 (-) 1662 WP_245061098.1 ABC transporter permease/substrate-binding protein -
  MPG53_RS03155 (MPG53_03155) - 649770..650207 (-) 438 WP_245061100.1 hypothetical protein -
  MPG53_RS03160 (MPG53_03160) motB 650211..650978 (-) 768 WP_245061102.1 flagellar motor protein MotB -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68815.05 Da        Isoelectric Point: 9.6981

>NTDB_id=667471 MPG53_RS03130 WP_245061094.1 644853..646637(-) (uvrC) [Helicobacter pylori strain Hpfe036]
MADLLSSLKNLSHSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSVRNNEITPNYRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYSKIAKKCLEMIENKDKLIKELELKMEHLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGSNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEVRSLFQLECMPYRVEIFDT
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYTQMSELLTRRALDFTKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTANDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=667471 MPG53_RS03130 WP_245061094.1 644853..646637(-) (uvrC) [Helicobacter pylori strain Hpfe036]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCTGTCCGTAATAATGAAATCACGCCCA
ATTATCGTGCAAGCTTACGCATCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTAGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAGCCAAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTATATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCATTAGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTCAAAAATCGCTAAAAAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCACCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATAGTGGGAGCAATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTTAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCTGAACAAATCTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCTCATCAATACTCTAAAAAAATCGCTCTTAGTATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGTGCGATCGCTCTTTCAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTACCAAAGAGC
CGCCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATCAT
CCACACCGCTAACGATACTTTTAAATTGCTCCCTAGCGACAAGCGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATTTAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.465

100

0.965

Multiple sequence alignment