Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   MPG35_RS00700 Genome accession   NZ_CP094138
Coordinates   150452..151195 (+) Length   247 a.a.
NCBI ID   WP_000660533.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe037     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 145452..156195
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG35_RS00675 (MPG35_00675) panD 147605..147955 (+) 351 WP_000142212.1 aspartate 1-decarboxylase -
  MPG35_RS00680 (MPG35_00680) - 147965..148258 (+) 294 WP_000347923.1 YbaB/EbfC family nucleoid-associated protein -
  MPG35_RS00685 (MPG35_00685) - 148258..149253 (+) 996 WP_245019996.1 PDZ domain-containing protein -
  MPG35_RS00690 (MPG35_00690) comB6 149259..150314 (+) 1056 WP_245019997.1 type IV secretion system protein Machinery gene
  MPG35_RS00695 (MPG35_00695) comB7 150330..150455 (+) 126 WP_001217867.1 hypothetical protein Machinery gene
  MPG35_RS00700 (MPG35_00700) comB8 150452..151195 (+) 744 WP_000660533.1 virB8 family protein Machinery gene
  MPG35_RS00705 (MPG35_00705) comB9 151195..152157 (+) 963 WP_245019680.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  MPG35_RS00710 (MPG35_00710) comB10 152150..153286 (+) 1137 WP_245019681.1 DNA type IV secretion system protein ComB10 Machinery gene
  MPG35_RS00715 (MPG35_00715) - 153356..154768 (+) 1413 WP_245019682.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  MPG35_RS00720 (MPG35_00720) gmd 154782..155927 (+) 1146 WP_120902685.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28670.89 Da        Isoelectric Point: 8.9546

>NTDB_id=667447 MPG35_RS00700 WP_000660533.1 150452..151195(+) (comB8) [Helicobacter pylori strain Hpfe037]
MKEKPFNSEQLIYLEELLSHQEKHLENKLSGFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAVVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLMNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKVTRYSITEI
APTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=667447 MPG35_RS00700 WP_000660533.1 150452..151195(+) (comB8) [Helicobacter pylori strain Hpfe037]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAATTGATCTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTGTTTAGATTAGAGAGGAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGCTTGATGAGTTTTATCGCTCTTGTTTTAGCGGTTGTTTTAATCAGTGTTTTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAGAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAACCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGCTCTAAAGTGTGGCAACGCTTTGAAGATTTGATTAAAACCCAAAACAGCATTTAT
GCACAAAGCCATTTGGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
TTCTATTGCGGCTAAACTCATGAATGAAAACAAACTGGTGTATGAAAAGCGTTATAAAATCGTGCTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCCAAAAACCCTACCGGCTTTAAAGTCACTCGCTACAGCATCACTGAAATC
GCACCGACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

96.761

100

0.968

Multiple sequence alignment