Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   MPF95_RS03165 Genome accession   NZ_CP094136
Coordinates   653283..655067 (-) Length   594 a.a.
NCBI ID   WP_245067571.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe039     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 648283..660067
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPF95_RS03135 (MPF95_03135) - 648863..649111 (+) 249 WP_000790557.1 RNA-binding protein -
  MPF95_RS03140 (MPF95_03140) - 649324..650145 (-) 822 WP_245067569.1 glycosyltransferase family 25 protein -
  MPF95_RS03145 (MPF95_03145) trxB 650312..651247 (-) 936 WP_120945573.1 thioredoxin-disulfide reductase -
  MPF95_RS03150 (MPF95_03150) trxA 651253..651573 (-) 321 WP_220853010.1 thioredoxin -
  MPF95_RS03155 (MPF95_03155) - 651662..652006 (-) 345 WP_001211650.1 YraN family protein -
  MPF95_RS03160 (MPF95_03160) - 652007..653272 (-) 1266 WP_057112449.1 homoserine dehydrogenase -
  MPF95_RS03165 (MPF95_03165) uvrC 653283..655067 (-) 1785 WP_245067571.1 excinuclease ABC subunit UvrC Machinery gene
  MPF95_RS03170 (MPF95_03170) - 655068..655529 (-) 462 WP_245067573.1 hypothetical protein -
  MPF95_RS03175 (MPF95_03175) - 655521..655700 (+) 180 WP_000468796.1 hypothetical protein -
  MPF95_RS03180 (MPF95_03180) - 655712..656353 (-) 642 WP_245067574.1 ATP-binding cassette domain-containing protein -
  MPF95_RS03185 (MPF95_03185) - 656357..658018 (-) 1662 WP_245067576.1 ABC transporter permease/substrate-binding protein -
  MPF95_RS03190 (MPF95_03190) - 658198..658635 (-) 438 WP_001031792.1 hypothetical protein -
  MPF95_RS03195 (MPF95_03195) motB 658639..659406 (-) 768 WP_245067585.1 flagellar motor protein MotB -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68809.98 Da        Isoelectric Point: 9.5694

>NTDB_id=667408 MPF95_RS03165 WP_245067571.1 653283..655067(-) (uvrC) [Helicobacter pylori strain Hpfe039]
MADLLSSLKNLSHSSGVYQYFDKNHQLLYIGKAKNLKKRIRSYFSIHNNEITPNYRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSSNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGSNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFQLECMPYRVEIFDT
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYTQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGTKDIIHTANDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=667408 MPF95_RS03165 WP_245067571.1 653283..655067(-) (uvrC) [Helicobacter pylori strain Hpfe039]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCACCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAGAAGCTATTTTTCTATCCACAATAATGAAATCACGCCCA
ATTATCGCGCGAGCTTACGAATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAACAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAACAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGTCCTTTTACGAGCGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTGAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAGCAATTTGCGTTTTGAAGAAGCCCTCATTTATAGGGATAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATAGCGGGAGCAATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTTAATGGGTTTGACA
CTGATGAAGCAATGAAACAAGCTATTATCAATCATTACCAATCGCATTTGCCTTTAATGCCTGAACAAATCTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCTCACCAATACTCTAAAAAAATCGCTCTTAGTATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTCTTTCAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTGCCAAAGAGC
CGCCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGCACAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCACTAAAGACATCAT
CCACACCGCTAACGATACTTTTAAATTGCTTCCTAGCGACAAGCGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAAGGCATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATTTAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.633

100

0.966

Multiple sequence alignment