Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   MPG28_RS04485 Genome accession   NZ_CP094135
Coordinates   938952..940736 (+) Length   594 a.a.
NCBI ID   WP_245077361.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe040     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 933952..945736
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG28_RS04455 (MPG28_04455) motB 934615..935382 (+) 768 WP_021301758.1 flagellar motor protein MotB -
  MPG28_RS04460 (MPG28_04460) - 935386..935823 (+) 438 WP_245077355.1 hypothetical protein -
  MPG28_RS04465 (MPG28_04465) - 936003..937664 (+) 1662 WP_245077357.1 ABC transporter permease/substrate-binding protein -
  MPG28_RS04470 (MPG28_04470) - 937666..938307 (+) 642 WP_245077359.1 ATP-binding cassette domain-containing protein -
  MPG28_RS04475 (MPG28_04475) - 938319..938498 (-) 180 WP_000468796.1 hypothetical protein -
  MPG28_RS04480 (MPG28_04480) - 938490..938951 (+) 462 WP_000437189.1 hypothetical protein -
  MPG28_RS04485 (MPG28_04485) uvrC 938952..940736 (+) 1785 WP_245077361.1 excinuclease ABC subunit UvrC Machinery gene
  MPG28_RS04490 (MPG28_04490) - 940747..942012 (+) 1266 WP_057112449.1 homoserine dehydrogenase -
  MPG28_RS04495 (MPG28_04495) - 942013..942357 (+) 345 WP_180400925.1 YraN family protein -
  MPG28_RS04500 (MPG28_04500) trxA 942446..942766 (+) 321 WP_000020200.1 thioredoxin -
  MPG28_RS04505 (MPG28_04505) trxB 942772..943707 (+) 936 WP_245077363.1 thioredoxin-disulfide reductase -
  MPG28_RS04510 (MPG28_04510) - 943887..944708 (+) 822 WP_245077372.1 glycosyltransferase family 25 protein -
  MPG28_RS04515 (MPG28_04515) - 944915..945163 (-) 249 WP_000790557.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68843.05 Da        Isoelectric Point: 9.6114

>NTDB_id=667390 MPG28_RS04485 WP_245077361.1 938952..940736(+) (uvrC) [Helicobacter pylori strain Hpfe040]
MADLLSSLKNLSHSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSVRNNEITPNYRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGSNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQDFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEAQSLFKLECMPYRVEIFDT
SHHTNSQCVGGMVVYENHEFQKNSYRHYHLKGSNEYTQMSELLTRRALDFNKEPPPNLWVIDGGRVQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTANDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=667390 MPG28_RS04485 WP_245077361.1 938952..940736(+) (uvrC) [Helicobacter pylori strain Hpfe040]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTCACAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGTTATTTTTCTGTCCGTAATAATGAAATCACGCCCA
ATTATCGTGCAAGCTTACGCATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGATGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGTGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCTCTCATTTATAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATAGTGGGAGCAATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTTAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCAGAACAAATCTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGATTTTATCTCTCACCAATACTCTAAAAAAATCGCTCTTAGTATTCC
TAAAAAAGGCGATAAACTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCAATCGCTCTTTAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATACCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGAATTTCAAAAAAACTCCTATCGGCA
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAGTTGCTCACCAGAAGGGCTTTAGATTTTAATAAAGAGC
CACCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGTGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CCACACCGCTAACGATACTTTTAAATTGCTCCCTAGCGACAAGCGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(384-538)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.633

100

0.966

Multiple sequence alignment