Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   MPG50_RS07245 Genome accession   NZ_CP094134
Coordinates   1516311..1518674 (-) Length   787 a.a.
NCBI ID   WP_245032112.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe048     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1511311..1523674
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG50_RS07220 (MPG50_07220) lpxE 1511828..1512361 (+) 534 WP_245033191.1 lipid A 1-phosphatase LpxE -
  MPG50_RS07225 (MPG50_07225) nspC 1512371..1513588 (-) 1218 WP_245032106.1 carboxynorspermidine decarboxylase -
  MPG50_RS07230 (MPG50_07230) cheV1 1513585..1514550 (-) 966 WP_245032108.1 chemotaxis protein CheV1 -
  MPG50_RS07235 (MPG50_07235) - 1514651..1515991 (-) 1341 WP_245032110.1 hypothetical protein -
  MPG50_RS07245 (MPG50_07245) comB4 1516311..1518674 (-) 2364 WP_245032112.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  MPG50_RS07250 (MPG50_07250) comB3 1518677..1518940 (-) 264 WP_000584953.1 hypothetical protein Machinery gene
  MPG50_RS07255 (MPG50_07255) comB2 1518940..1519221 (-) 282 WP_001272686.1 TrbC/VirB2 family protein Machinery gene
  MPG50_RS07260 (MPG50_07260) - 1519366..1520193 (-) 828 WP_245032114.1 DUF5718 family protein -
  MPG50_RS07265 (MPG50_07265) - 1520283..1521335 (-) 1053 WP_245032116.1 MnmA/TRMU family protein -
  MPG50_RS07270 (MPG50_07270) dnaG 1521332..1523011 (-) 1680 WP_245032118.1 DNA primase -
  MPG50_RS07275 (MPG50_07275) groES 1523288..1523644 (+) 357 WP_120813873.1 co-chaperone GroES -

Sequence

Protein


Download         Length: 787 a.a.        Molecular weight: 90224.89 Da        Isoelectric Point: 9.1027

>NTDB_id=667377 MPG50_RS07245 WP_245032112.1 1516311..1518674(-) (comB4) [Helicobacter pylori strain Hpfe048]
MLEKLLSAIKQKVSNYFLGVLPKSYSMSEENNILGLYDEHFLLTKNENLVGILRLEGVSYTHLSTEQLQDLFTERQMALD
SLEKVVVRLVVKRRKIDHQQNIQTNSKYLQAILNQFENKEVYENQYFLVLESAHSLQGVLEHKKKSLMHANRENFKDILS
YKAHFLQETLKSLEIQLKNYAPKLLSSKEVLNFYAEYINGFDLPLKPLVGGYLSDSYIASSITFEKDYFTQESFNQKTYN
RLIGIKAYESERITSIAIGALLYQETPLDIIFSIEPMSVNKTLSFLKERAKFSMSNLVKNELLEYQELVKTKRLSMQKFA
LNILIKAPSLEDLDTQTSLVLGLLFKENLVGVIETFGLKGGYFSFFPERIHLNHRLRFLTSKALACLMVFERQNLGFKAN
SWGNSPLSVFKNLDYSPFLFNFHNQEVSHNNAKEIARVNGHTLIIGATGSGKSTLISFLMMSALKYQNMRLLAFDRMQGL
YSFTKFFKGHYHDGKSFSINPFCLEPNLQNLEFLQSFFLSMFDLAPSRDKEALEDMNAILGAIKSLYETLYPKAFSLLDF
KETLKRTSSNQLGLSLEPYLNNPLFNALNDAFNSNAFLNVINLDAITQNPKDLGLLAYYLFYKILEESRKNDSGFLVFLD
EFKSYVENDLLNAKINALVTQARKANGVVVLALQDIYQLSGVKNAHSFLSNMGTLILYPQKNARELKHHFNVPLSETEIS
FLENTPLYARQVLVKNLGNGSSNMIDVSLESLGRYLKIFNSDSSHVNKVKALQKDYPKEWREKLLKS

Nucleotide


Download         Length: 2364 bp        

>NTDB_id=667377 MPG50_RS07245 WP_245032112.1 1516311..1518674(-) (comB4) [Helicobacter pylori strain Hpfe048]
ATGTTAGAAAAGCTTTTGAGCGCCATCAAACAAAAAGTTTCAAACTATTTTTTAGGGGTTTTGCCTAAAAGCTATTCTAT
GAGCGAAGAAAACAACATTTTAGGTTTGTATGATGAGCATTTCTTACTCACTAAAAACGAAAACTTAGTGGGAATCCTCC
GTTTAGAGGGGGTGAGTTACACCCATTTAAGCACGGAGCAATTGCAAGATCTTTTCACCGAGCGCCAAATGGCGTTGGAT
TCTTTAGAAAAAGTTGTGGTGCGCCTTGTGGTTAAAAGGCGTAAAATTGATCACCAACAAAACATTCAAACTAATTCCAA
ATACTTGCAAGCGATTTTGAATCAATTTGAAAATAAAGAAGTGTATGAAAATCAGTATTTTTTAGTTTTAGAAAGCGCGC
ACTCTTTACAGGGCGTTTTAGAGCATAAGAAAAAATCTCTTATGCATGCCAATAGGGAAAATTTTAAGGACATTCTCTCT
TATAAAGCGCATTTTTTGCAAGAAACTTTAAAAAGCCTAGAAATCCAGCTCAAAAACTATGCCCCCAAACTCTTAAGCTC
CAAAGAAGTTTTGAATTTTTATGCGGAATACATTAACGGGTTTGATCTCCCTTTAAAGCCCTTAGTAGGGGGGTATTTGA
GCGATAGCTATATCGCTAGTTCTATCACTTTTGAAAAAGATTATTTCACTCAAGAAAGCTTTAATCAAAAAACCTATAAC
CGCTTGATTGGCATTAAAGCTTATGAGAGCGAGCGCATCACTTCTATAGCGATCGGAGCGCTTTTATACCAAGAAACGCC
TTTAGACATTATCTTTTCTATAGAGCCTATGAGCGTCAATAAAACGCTGAGTTTTTTAAAAGAGAGGGCCAAATTTAGCA
TGTCCAATCTCGTTAAAAACGAGCTGCTAGAATACCAAGAACTGGTCAAAACCAAACGCCTATCCATGCAAAAATTTGCC
TTAAACATTCTTATCAAAGCCCCTAGTTTAGAGGATTTAGACACTCAAACAAGCTTAGTTTTAGGGCTTTTATTTAAAGA
AAACTTAGTGGGCGTTATAGAAACTTTTGGCTTGAAGGGGGGGTATTTTTCCTTTTTCCCTGAACGCATCCACTTAAACC
ACCGCTTGCGTTTTTTAACTTCTAAAGCCCTAGCGTGTTTAATGGTGTTTGAAAGGCAAAATTTAGGTTTTAAGGCTAAT
TCATGGGGGAATAGCCCTTTGAGCGTGTTTAAAAATTTGGATTATTCCCCCTTTTTATTCAATTTCCACAACCAAGAAGT
GAGCCATAACAACGCTAAAGAAATCGCCAGAGTGAATGGGCATACCTTAATTATAGGGGCTACCGGGAGCGGTAAAAGCA
CGCTGATTAGCTTTTTAATGATGAGCGCTTTGAAATACCAAAACATGCGCCTTTTAGCATTTGATAGGATGCAAGGGCTG
TATTCTTTCACAAAATTTTTTAAAGGGCATTACCATGACGGCAAATCTTTTAGCATCAACCCCTTTTGTTTAGAGCCTAA
TTTGCAGAATTTAGAATTTTTGCAATCCTTCTTTTTGAGCATGTTTGATCTTGCTCCTTCAAGGGATAAAGAAGCATTAG
AAGACATGAATGCGATTTTGGGCGCGATTAAGAGCCTTTATGAGACTTTATACCCTAAAGCTTTTAGTTTGTTAGATTTT
AAAGAAACGCTTAAAAGAACCTCATCCAATCAATTGGGTTTGAGTTTAGAGCCGTATTTGAATAACCCCCTTTTTAACGC
CTTGAATGACGCGTTCAACTCCAACGCTTTTTTAAATGTGATAAACCTAGATGCCATCACCCAAAACCCTAAAGACTTAG
GGCTTTTAGCCTATTATTTGTTTTATAAAATCTTAGAAGAATCCAGGAAAAACGACAGCGGTTTTTTGGTTTTTTTAGAC
GAGTTTAAATCCTATGTGGAAAACGATTTATTGAACGCTAAAATTAACGCTTTAGTCACGCAAGCCAGAAAGGCTAATGG
TGTGGTGGTGTTGGCTTTGCAAGACATTTACCAATTAAGCGGGGTTAAAAACGCCCATAGTTTTTTAAGCAACATGGGGA
CTCTTATTTTGTATCCGCAAAAAAACGCTAGGGAGTTGAAACACCATTTCAATGTGCCTTTGAGCGAAACTGAAATTTCT
TTTTTAGAAAACACCCCTTTGTATGCCAGGCAGGTTTTAGTCAAAAATCTGGGTAACGGGAGTTCTAACATGATTGATGT
GAGTTTGGAAAGCTTAGGGCGTTATTTGAAAATCTTTAATTCAGACTCTAGCCATGTGAATAAAGTGAAAGCGTTACAAA
AAGACTACCCTAAAGAGTGGCGTGAGAAACTTTTGAAGAGCTAG

Domains

Predicted by InterproScan.

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(176-375)

FtsK/SpoIIIE family (FtsK_SpoIIIE)

(426-466)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

97.332

100

0.973

Multiple sequence alignment