Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   MPG50_RS03095 Genome accession   NZ_CP094134
Coordinates   640614..642398 (-) Length   594 a.a.
NCBI ID   WP_245032913.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe048     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 635614..647398
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG50_RS03065 (MPG50_03065) - 636206..636454 (+) 249 WP_000790557.1 RNA-binding protein -
  MPG50_RS03070 (MPG50_03070) - 636660..637481 (-) 822 WP_245032909.1 glycosyltransferase family 25 protein -
  MPG50_RS03075 (MPG50_03075) trxB 637644..638579 (-) 936 WP_021301752.1 thioredoxin-disulfide reductase -
  MPG50_RS03080 (MPG50_03080) trxA 638585..638905 (-) 321 WP_245032911.1 thioredoxin -
  MPG50_RS03085 (MPG50_03085) - 638993..639337 (-) 345 WP_231173838.1 YraN family protein -
  MPG50_RS03090 (MPG50_03090) - 639338..640603 (-) 1266 WP_050850922.1 homoserine dehydrogenase -
  MPG50_RS03095 (MPG50_03095) uvrC 640614..642398 (-) 1785 WP_245032913.1 excinuclease ABC subunit UvrC Machinery gene
  MPG50_RS03100 (MPG50_03100) - 642399..642860 (-) 462 WP_120874094.1 hypothetical protein -
  MPG50_RS03105 (MPG50_03105) - 642852..643031 (+) 180 WP_000468796.1 hypothetical protein -
  MPG50_RS03110 (MPG50_03110) - 643043..643684 (-) 642 WP_245032915.1 ATP-binding cassette domain-containing protein -
  MPG50_RS03115 (MPG50_03115) - 643688..645349 (-) 1662 WP_245032917.1 ABC transporter permease/substrate-binding protein -
  MPG50_RS03120 (MPG50_03120) - 645531..645968 (-) 438 WP_001031792.1 hypothetical protein -
  MPG50_RS03125 (MPG50_03125) motB 645972..646739 (-) 768 WP_001085319.1 flagellar motor protein MotB -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68820.03 Da        Isoelectric Point: 9.6704

>NTDB_id=667365 MPG50_RS03095 WP_245032913.1 640614..642398(-) (uvrC) [Helicobacter pylori strain Hpfe048]
MADLLSSLKNLSHSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSVRNNEITPNHRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYSKIAKECLEMIENKDKLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGGNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQVIINHYQSHLPLMPEQILLN
ACSNETLKELQDFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEVRSLFQLECMPYRVEIFDT
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYTQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGDAKDIIHTANNTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=667365 MPG50_RS03095 WP_245032913.1 640614..642398(-) (uvrC) [Helicobacter pylori strain Hpfe048]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCTGTCCGTAATAATGAAATCACGCCCA
ATCATCGTGCAAGCTTACGCATCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTCTAGAAAATTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCCTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTGATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAAGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTCAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATAGTGGGGGTAATAAGGCGGT
GTTAGTAAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTCAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGTCATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCTGAACAAATCTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGATTTTATCTCTCACCAATACTCTAAAAAAATCGCTCTTAGTATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCCA
ATGAAGATCTGATTTTAGAAGAAGTGCGATCGCTCTTTCAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGACACC
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTGCCAAAGAGC
CGCCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGAGACGCTAAAGACATTAT
CCACACCGCTAACAATACTTTTAAATTGCTCCCTAGCGACAAGCGCTTGCAGTGGGTGCAAAAATTACGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAACAAGAAAAAAA
CGCCGTTTTAAAAAAACGAATTTAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.296

100

0.963

Multiple sequence alignment