Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   MPG50_RS00705 Genome accession   NZ_CP094134
Coordinates   150264..151007 (+) Length   247 a.a.
NCBI ID   WP_245032366.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe048     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 145264..156007
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG50_RS00680 (MPG50_00680) panD 147426..147776 (+) 351 WP_000142212.1 aspartate 1-decarboxylase -
  MPG50_RS00685 (MPG50_00685) - 147787..148080 (+) 294 WP_000347916.1 YbaB/EbfC family nucleoid-associated protein -
  MPG50_RS00690 (MPG50_00690) - 148080..149075 (+) 996 WP_245033084.1 PDZ domain-containing protein -
  MPG50_RS00695 (MPG50_00695) comB6 149083..150138 (+) 1056 WP_245033086.1 P-type conjugative transfer protein TrbL Machinery gene
  MPG50_RS00700 (MPG50_00700) comB7 150154..150267 (+) 114 WP_073422943.1 comB7 lipoprotein Machinery gene
  MPG50_RS00705 (MPG50_00705) comB8 150264..151007 (+) 744 WP_245032366.1 virB8 family protein Machinery gene
  MPG50_RS00710 (MPG50_00710) comB9 151007..151972 (+) 966 WP_245032368.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  MPG50_RS00715 (MPG50_00715) comB10 151965..153101 (+) 1137 WP_245032370.1 DNA type IV secretion system protein ComB10 Machinery gene
  MPG50_RS00720 (MPG50_00720) - 153171..154583 (+) 1413 WP_245032372.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  MPG50_RS00725 (MPG50_00725) gmd 154598..155743 (+) 1146 WP_245032374.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28718.93 Da        Isoelectric Point: 8.9546

>NTDB_id=667361 MPG50_RS00705 WP_245032366.1 150264..151007(+) (comB8) [Helicobacter pylori strain Hpfe048]
MKEKPFNSEQLIYLEELLSHQEKHLENKLSGFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAIVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAFYQQDNNPIASVSIAAKLMNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKVTRYSITEI
APTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=667361 MPG50_RS00705 WP_245032366.1 150264..151007(+) (comB8) [Helicobacter pylori strain Hpfe048]
ATGAAGGAAAAGCCTTTCAATAGCGAGCAATTGATCTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTGTTTAGATTGGAGAGGAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGCTTGATGAGTTTTATCGCTCTTGTTTTAGCGATTGTTTTAATCAGTGTTTTACCCCTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAACCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAAGATTTGATTAAAACCCAAAACAGCATTTAT
GCGCAAAGCCATTTGGAAAGAGAAGTCCATATCGTCAATATTGCGTTCTATCAGCAAGACAATAACCCCATTGCGAGCGT
CTCCATTGCGGCTAAACTCATGAACGAAAACAAGCTGGTGTATGAAAAGCGTTATAAAATCGTGCTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAGTTACTCGCTACAGCATCACTGAAATC
GCGCCGACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

96.761

100

0.968

Multiple sequence alignment