Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   MPG30_RS04460 Genome accession   NZ_CP094131
Coordinates   942583..944367 (+) Length   594 a.a.
NCBI ID   WP_245047071.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe052     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 937583..949367
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG30_RS04430 (MPG30_04430) motB 938243..939010 (+) 768 WP_001085319.1 flagellar motor protein MotB -
  MPG30_RS04435 (MPG30_04435) - 939014..939451 (+) 438 WP_001031792.1 hypothetical protein -
  MPG30_RS04440 (MPG30_04440) - 939631..941292 (+) 1662 WP_245047065.1 ABC transporter permease/substrate-binding protein -
  MPG30_RS04445 (MPG30_04445) - 941297..941938 (+) 642 WP_245047067.1 ATP-binding cassette domain-containing protein -
  MPG30_RS04450 (MPG30_04450) - 941950..942129 (-) 180 WP_000468796.1 hypothetical protein -
  MPG30_RS04455 (MPG30_04455) - 942121..942582 (+) 462 WP_245047069.1 hypothetical protein -
  MPG30_RS04460 (MPG30_04460) uvrC 942583..944367 (+) 1785 WP_245047071.1 excinuclease ABC subunit UvrC Machinery gene
  MPG30_RS04465 (MPG30_04465) - 944378..945643 (+) 1266 WP_245047073.1 homoserine dehydrogenase -
  MPG30_RS04470 (MPG30_04470) - 945644..945988 (+) 345 WP_096468309.1 YraN family protein -
  MPG30_RS04475 (MPG30_04475) trxA 946077..946397 (+) 321 WP_000020200.1 thioredoxin -
  MPG30_RS04480 (MPG30_04480) trxB 946403..947338 (+) 936 WP_154410486.1 thioredoxin-disulfide reductase -
  MPG30_RS04485 (MPG30_04485) - 947505..948326 (+) 822 WP_245047075.1 glycosyltransferase family 25 protein -
  MPG30_RS04490 (MPG30_04490) - 948521..948769 (-) 249 WP_000790556.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68729.99 Da        Isoelectric Point: 9.7098

>NTDB_id=667305 MPG30_RS04460 WP_245047071.1 942583..944367(+) (uvrC) [Helicobacter pylori strain Hpfe052]
MADLLSSLKNLSHSSGVYQYFDKNHQLLYIGKAKNLKKRIKSYFSVRNNEITPNHRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGSNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLS
ACSNETLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFKLECMPYRVEIFDT
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYTQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTANNTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=667305 MPG30_RS04460 WP_245047071.1 942583..944367(+) (uvrC) [Helicobacter pylori strain Hpfe052]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTCATAGCAGCGGCGTGTATCAATATTTTGATAAAAACCACCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGTATCAAAAGCTATTTTTCTGTCCGTAATAATGAAATCACGCCCA
ATCATCGTGCAAGCTTACGAATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAACTCTTTAATCAAACAGCTCAAACCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAAGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATAGTGGGAGCAATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTCAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCTATCATCAATCATTACCAATCGCATTTGCCCTTAATGCCTGAACAAATCTTATTGAGC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCTCATCAATACTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGTCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTCTTTAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAACCATGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTGCCAAAGAGC
CGCCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGAGGTGCTAAAGACATTAT
CCATACCGCTAACAATACTTTTAAATTGCTCCCTAGCGACAAGCGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTGTTAGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCTGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

97.138

100

0.971

Multiple sequence alignment