Detailed information NTG0066730

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: SAJPND1_RS13530
• Genome accession: NZ_AP014652
• Coordinates: 2667905..2668792 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain TMUS2126
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2662905..2673792

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAJPND1_RS13495 (AXW71_RS13470)	-	2662923..2663015 (+)	93	WP_010956583.1	hypothetical protein	-
SAJPND1_RS13500 (AXW71_RS13475)	-	2663123..2663620 (-)	498	WP_001065269.1	glutathione peroxidase	-
SAJPND1_RS13505 (AXW71_RS13480)	-	2663630..2663890 (-)	261	WP_001789910.1	hypothetical protein	-
SAJPND1_RS13515 (AXW71_RS13485)	-	2664272..2664385 (-)	114	Protein_2574	hypothetical protein	-
SAJPND1_RS13520 (AXW71_RS13495)	-	2665044..2667044 (-)	2001	WP_000776739.1	ABC transporter permease	-
SAJPND1_RS13525 (AXW71_RS13500)	-	2667041..2667796 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
SAJPND1_RS13530 (AXW71_RS13505)	braS	2667905..2668792 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
SAJPND1_RS13535 (AXW71_RS13510)	braR	2668803..2669468 (-)	666	WP_000697879.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
SAJPND1_RS13540 (AXW71_RS13515)	-	2669494..2669694 (-)	201	WP_000604727.1	hypothetical protein	-
SAJPND1_RS13545 (AXW71_RS13525)	-	2669892..2671316 (+)	1425	WP_000953762.1	alkaline phosphatase	-
SAJPND1_RS14040 (SAJPND1_02637)	-	2671386..2671496 (+)	111	WP_001791296.1	hypothetical protein	-
SAJPND1_RS13555 (AXW71_RS13530)	-	2671599..2672054 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
SAJPND1_RS13560 (AXW71_RS13535)	-	2672299..2673060 (-)	762	WP_000323447.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=66730 SAJPND1_RS13530 WP_000143420.1 2667905..2668792(-) (braS) [Staphylococcus aureus strain TMUS2126]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=66730 SAJPND1_RS13530 WP_000143420.1 2667905..2668792(-) (braS) [Staphylococcus aureus strain TMUS2126]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993