Detailed information NTG0667267

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: OG239_RS24520
• Genome accession: NZ_CP108814
• Coordinates: 5064370..5066895 (+)
• Length: 841 a.a.
• NCBI ID: WP_328926962.1
• Uniprot ID: -
• Organism: Streptomyces sp. NBC_00868
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 5059370..5071895

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OG239_RS24485 (OG239_24465)	-	5060630..5060815 (+)	186	WP_328926956.1	DUF397 domain-containing protein	-
OG239_RS24490 (OG239_24470)	-	5060913..5061497 (+)	585	WP_328930365.1	hypothetical protein	-
OG239_RS24495 (OG239_24475)	-	5061512..5061679 (+)	168	WP_328926957.1	hypothetical protein	-
OG239_RS24500 (OG239_24480)	-	5061788..5062273 (+)	486	WP_405679108.1	BlaI/MecI/CopY family transcriptional regulator	-
OG239_RS24505 (OG239_24485)	-	5062285..5062815 (+)	531	WP_328926959.1	amino-acid N-acetyltransferase	-
OG239_RS24510 (OG239_24490)	-	5062981..5063319 (+)	339	WP_405679105.1	Lsr2 family protein	-
OG239_RS24515 (OG239_24495)	-	5063298..5063882 (-)	585	WP_405679103.1	SCO3374 family protein	-
OG239_RS24520 (OG239_24500)	clpC	5064370..5066895 (+)	2526	WP_328926962.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
OG239_RS24525 (OG239_24505)	-	5066977..5067480 (-)	504	WP_405679101.1	hypothetical protein	-
OG239_RS24530 (OG239_24510)	-	5068037..5069170 (-)	1134	WP_405679099.1	NACHT domain-containing protein	-
OG239_RS24535 (OG239_24515)	-	5069149..5069427 (-)	279	Protein_4836	hypothetical protein	-
OG239_RS24540 (OG239_24520)	-	5069680..5070231 (+)	552	WP_328926964.1	M23 family metallopeptidase	-
OG239_RS24545 (OG239_24525)	-	5070299..5071516 (-)	1218	WP_328926965.1	LamG-like jellyroll fold domain-containing protein	-

Sequence

Protein

• Length: 841 a.a.
• Molecular weight: 92960.22 Da
• Isoelectric Point: 5.8420

>NTDB_id=667267 OG239_RS24520 WP_328926962.1 5064370..5066895(+) (clpC) [Streptomyces sp. NBC_00868]
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKALESLGISLEAVRQQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGADLNRVRQQVIQLLSGYTGGGKESATAGGPAE
GTPSTSLVLDQFGRNLTQAARESKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVKGEVPETL
KDKHLYTLDLGALVAGSRYRGDFEERLKKVLKEIRTRGDIILFIDELHTLVGAGAAEGAIDAASILKPMLARGELQTIGA
TTLDEYRKHLEKDAALERRFQPIQVAEPSLPHTIEILKGLRDRYEAHHRVSITDEALVQAATLADRYISDRFLPDKAIDL
IDEAGSRMRIRRMTAPPDLREFDEKIAAVRRDKESAIDSQDFEKAASLRDKEKQLLAAKAKREKEWKAGDMDVVAEVDGE
LIAEVLATATGIPVFKLTEEESSRLLRMEDELHRRVIGQKDAIKALSQAIRRTRAGLKDPKRPGGSFIFAGPSGVGKTEL
SKTLAEFLFGDEDALISLDMSEFSEKHTVSRLFGSPPGYVGYEEGGQLTEKVRRKPFSVVLFDEVEKAHPDIFNSLLQIL
EDGRLTDSQGRVVDFKNTVIIMTTNLGTRDISKGFNLGFAAQGDTKTGYERMKAKVNEELKQHFRPEFLNRVDDTVVFHQ
LTEEDIIQIVDLMIAKVDERLKDRDMGIELSGDAKLLLAKRGYDPIMGARPLRRTIQREIEDLLSEKILFGELRPGQIVV
VGKEGEGDDAKFTFRGEEKSALPDLPPIEATGSGPDLSKGA

Nucleotide

• Length: 2526 bp

>NTDB_id=667267 OG239_RS24520 WP_328926962.1 5064370..5066895(+) (clpC) [Streptomyces sp. NBC_00868]
ATGTTCGAGAGGTTCACCGACCGCGCGCGGCGGGTTGTCGTCCTGGCTCAGGAAGAAGCCCGGATGCTCAACCACAACTA
CATCGGCACCGAGCACATCCTCCTGGGCTTGATCCACGAGGGTGAGGGTGTCGCCGCTAAGGCCCTGGAGAGCCTCGGGA
TTTCGCTCGAGGCTGTTCGCCAGCAGGTTGAGGAGATCATCGGTCAGGGGCAGCAGGCCCCGTCCGGCCACATCCCCTTC
ACCCCGCGGGCGAAGAAGGTCCTGGAGCTGTCGCTCCGAGAGGCCCTCCAGCTCGGCCACAACTACATCGGCACCGAGCA
CATCCTGCTCGGCCTGATCCGCGAGGGCGAGGGCGTCGCCGCCCAGGTCCTCGTGAAGCTGGGCGCCGATCTCAACCGAG
TCCGGCAGCAGGTCATCCAGCTGCTCTCCGGCTACACCGGCGGAGGCAAGGAGTCGGCCACGGCCGGCGGCCCGGCCGAG
GGCACGCCCTCGACCTCGCTCGTCCTGGACCAGTTCGGCCGCAACCTCACCCAGGCGGCCCGCGAATCCAAGCTCGACCC
GGTCATCGGGCGCGAGAAGGAGATCGAGCGGGTCATGCAGGTGCTGTCCCGCCGTACCAAGAACAACCCGGTCCTCATCG
GCGAGCCCGGCGTCGGCAAGACCGCCGTCGTCGAGGGCCTGGCCCAGGCGATCGTCAAGGGCGAGGTCCCCGAGACCCTC
AAGGACAAGCACCTCTACACGCTTGACCTGGGTGCCCTGGTCGCCGGTTCCCGCTACCGCGGTGACTTCGAGGAGCGCCT
GAAGAAGGTGCTCAAGGAGATCCGCACCCGCGGCGACATCATCCTGTTCATCGACGAGCTCCACACCCTCGTGGGTGCGG
GCGCCGCCGAGGGCGCGATCGACGCCGCCAGCATCCTCAAGCCCATGCTGGCCCGTGGTGAGCTCCAGACCATCGGTGCC
ACGACGCTGGACGAGTACCGCAAGCACCTCGAGAAGGACGCGGCCCTCGAGCGCCGCTTCCAGCCGATCCAGGTGGCGGA
GCCTTCCCTCCCCCACACGATCGAGATCCTCAAGGGCCTGCGCGACCGCTACGAGGCCCACCACCGCGTCTCCATCACGG
ACGAGGCCCTCGTCCAGGCGGCGACGCTGGCGGACCGGTACATCTCGGACCGCTTCCTCCCGGACAAGGCGATCGACCTG
ATCGACGAGGCCGGCTCCCGGATGCGCATCCGCCGGATGACCGCGCCGCCGGACCTCCGCGAGTTCGACGAGAAGATCGC
GGCCGTGCGCCGCGACAAGGAGTCGGCCATCGACTCCCAGGACTTCGAGAAGGCGGCGTCTCTCCGTGACAAGGAGAAGC
AGCTGCTGGCGGCGAAGGCCAAGCGCGAGAAGGAATGGAAGGCCGGCGACATGGACGTCGTCGCCGAGGTCGACGGCGAG
CTCATCGCCGAAGTCCTCGCGACCGCGACCGGCATTCCCGTCTTCAAGCTCACCGAGGAGGAGTCCTCGCGACTGCTCCG
CATGGAGGACGAGCTCCACCGTCGGGTCATCGGCCAGAAGGACGCCATCAAGGCGCTCTCGCAGGCGATCCGCCGTACCC
GTGCGGGTCTGAAGGACCCGAAGCGCCCGGGTGGCTCGTTCATCTTCGCCGGTCCGTCCGGTGTCGGTAAGACCGAGCTC
TCCAAGACGCTCGCCGAATTCCTCTTCGGTGACGAGGACGCGCTGATCTCCCTCGACATGTCGGAGTTCAGCGAGAAGCA
CACGGTTTCCCGTCTCTTCGGTTCGCCCCCCGGCTACGTGGGCTACGAAGAGGGCGGCCAGCTCACCGAGAAGGTGCGCC
GGAAGCCGTTCTCCGTCGTCCTCTTCGACGAGGTCGAGAAGGCCCACCCGGATATCTTCAATTCCCTTCTCCAGATCCTG
GAGGACGGTCGCCTGACCGACTCCCAGGGCCGGGTCGTGGACTTCAAGAACACGGTCATCATCATGACGACCAACCTGGG
TACCCGGGACATCTCGAAGGGCTTCAACCTGGGCTTCGCGGCCCAGGGCGACACCAAGACCGGCTACGAGCGGATGAAGG
CGAAGGTCAACGAAGAGCTCAAGCAGCACTTCCGGCCCGAGTTCCTCAACCGCGTCGACGACACGGTCGTCTTCCACCAG
CTCACCGAGGAAGACATCATCCAGATCGTCGACCTGATGATCGCGAAGGTCGACGAGCGCCTGAAGGACCGCGACATGGG
CATCGAGCTGAGCGGTGACGCGAAGCTCCTGCTCGCCAAGCGCGGCTACGACCCGATCATGGGTGCCCGGCCGCTGCGCC
GGACCATCCAGCGCGAGATCGAGGACCTGCTGTCGGAGAAGATCCTCTTCGGCGAGCTGCGTCCCGGTCAGATCGTGGTC
GTCGGCAAGGAGGGTGAGGGCGACGACGCCAAGTTCACCTTCCGCGGCGAGGAGAAGTCGGCTCTGCCGGACCTCCCCCC
GATCGAGGCCACGGGCTCCGGCCCGGACCTGTCGAAGGGCGCGTAA

Domains

Predicted by InterProScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (93-142)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (16-68)

• AAA lid domain (AAA_lid_9) (351-451)

• AAA domain (Cdc48 subfamily) (AAA_2) (543-714)

• ATPase family associated with various cellular activities (AAA) (AAA) (211-331)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (721-801)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	60.61	97.503	0.591
clpC	Streptococcus mutans UA159	44.699	98.692	0.441
clpC	Streptococcus thermophilus LMD-9	43.69	99.881	0.436
clpC	Streptococcus thermophilus LMG 18311	43.52	100	0.435
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	44.212	96.552	0.427
clpC	Streptococcus pneumoniae Rx1	44.195	95.244	0.421
clpC	Streptococcus pneumoniae D39	44.195	95.244	0.421
clpC	Streptococcus pneumoniae TIGR4	43.945	95.244	0.419
clpE	Streptococcus mutans UA159	53.674	74.435	0.4
clpE	Streptococcus pneumoniae TIGR4	51.887	75.624	0.392
clpE	Streptococcus pneumoniae R6	51.73	75.624	0.391
clpE	Streptococcus pneumoniae Rx1	51.73	75.624	0.391
clpE	Streptococcus pneumoniae D39	51.73	75.624	0.391
clpC	Lactococcus lactis subsp. cremoris KW2	52.419	73.722	0.386