Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   MPG85_RS00730 Genome accession   NZ_CP094129
Coordinates   152544..153287 (+) Length   247 a.a.
NCBI ID   WP_245050849.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe054     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 147544..158287
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG85_RS00705 (MPG85_00705) panD 149694..150044 (+) 351 WP_245050843.1 aspartate 1-decarboxylase -
  MPG85_RS00710 (MPG85_00710) - 150055..150348 (+) 294 WP_000347916.1 YbaB/EbfC family nucleoid-associated protein -
  MPG85_RS00715 (MPG85_00715) - 150348..151343 (+) 996 WP_245051473.1 PDZ domain-containing protein -
  MPG85_RS00720 (MPG85_00720) comB6 151351..152406 (+) 1056 WP_245050845.1 P-type conjugative transfer protein TrbL Machinery gene
  MPG85_RS00725 (MPG85_00725) comB7 152422..152547 (+) 126 WP_245050847.1 comB7 lipoprotein Machinery gene
  MPG85_RS00730 (MPG85_00730) comB8 152544..153287 (+) 744 WP_245050849.1 virB8 family protein Machinery gene
  MPG85_RS00735 (MPG85_00735) comB9 153287..154252 (+) 966 WP_245050851.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  MPG85_RS00740 (MPG85_00740) comB10 154245..155381 (+) 1137 WP_245050853.1 DNA type IV secretion system protein ComB10 Machinery gene
  MPG85_RS00745 (MPG85_00745) - 155447..156859 (+) 1413 WP_245050855.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  MPG85_RS00750 (MPG85_00750) gmd 156874..158019 (+) 1146 WP_245050857.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28726.99 Da        Isoelectric Point: 8.9546

>NTDB_id=667255 MPG85_RS00730 WP_245050849.1 152544..153287(+) (comB8) [Helicobacter pylori strain Hpfe054]
MKEKPFNSEQLIYLEELLSHQEKHLENKLSGFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIALILAIVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
VQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLMNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKVTRYSITEI
APTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=667255 MPG85_RS00730 WP_245050849.1 152544..153287(+) (comB8) [Helicobacter pylori strain Hpfe054]
ATGAAGGAAAAGCCTTTCAATAGCGAGCAATTGATCTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTGTTTAGATTAGAGAGGAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGCTTGATGAGTTTTATCGCTCTTATCTTAGCGATTGTTTTAATCAGTGTTCTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTTATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAATCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAGGATTTGATCAAAACGCAAAACAGCATTTAT
GTGCAAAGCCATTTGGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
CTCCATTGCGGCTAAACTCATGAACGAAAACAAGCTGGTGTATGAAAAGCGTTATAAAATCGTGCTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAGTTACTCGCTACAGCATCACTGAAATC
GCACCGACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

97.976

100

0.98

Multiple sequence alignment