Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   MPG41_RS03110 Genome accession   NZ_CP094109
Coordinates   649552..651336 (-) Length   594 a.a.
NCBI ID   WP_245068378.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe072     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 644552..656336
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG41_RS03080 (MPG41_03080) - 645134..645382 (+) 249 WP_000790557.1 RNA-binding protein -
  MPG41_RS03085 (MPG41_03085) - 645593..646414 (-) 822 WP_245068374.1 glycosyltransferase family 25 protein -
  MPG41_RS03090 (MPG41_03090) trxB 646581..647516 (-) 936 WP_180535080.1 thioredoxin-disulfide reductase -
  MPG41_RS03095 (MPG41_03095) trxA 647522..647842 (-) 321 WP_057112447.1 thioredoxin -
  MPG41_RS03100 (MPG41_03100) - 647931..648275 (-) 345 WP_001211649.1 YraN family protein -
  MPG41_RS03105 (MPG41_03105) - 648276..649541 (-) 1266 WP_245068376.1 homoserine dehydrogenase -
  MPG41_RS03110 (MPG41_03110) uvrC 649552..651336 (-) 1785 WP_245068378.1 excinuclease ABC subunit UvrC Machinery gene
  MPG41_RS03115 (MPG41_03115) - 651337..651798 (-) 462 WP_000437191.1 hypothetical protein -
  MPG41_RS03120 (MPG41_03120) - 651790..651969 (+) 180 WP_000468796.1 hypothetical protein -
  MPG41_RS03125 (MPG41_03125) - 651981..652622 (-) 642 WP_245068380.1 ATP-binding cassette domain-containing protein -
  MPG41_RS03130 (MPG41_03130) - 652626..654287 (-) 1662 WP_245068382.1 ABC transporter permease/substrate-binding protein -
  MPG41_RS03135 (MPG41_03135) - 654648..655466 (+) 819 WP_245068383.1 site-specific DNA-methyltransferase -
  MPG41_RS03140 (MPG41_03140) - 655460..655630 (+) 171 WP_245068384.1 hypothetical protein -
  MPG41_RS03145 (MPG41_03145) - 655674..656030 (+) 357 WP_245068554.1 endonuclease VII domain-containing protein -
  MPG41_RS03150 (MPG41_03150) - 656042..656293 (-) 252 Protein_607 osmoprotection protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68790.13 Da        Isoelectric Point: 9.7848

>NTDB_id=666959 MPG41_RS03110 WP_245068378.1 649552..651336(-) (uvrC) [Helicobacter pylori strain Hpfe072]
MADLLSSLKNLSHSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSVRNNEITPNHRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGNNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQEFISHKYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFKLECMPYRVEIFDT
SHHANSQCVGGMVVYENHAFQKNSYRRYHLKGSNEYTQMSELLTRRALDFAKEPPPNLWVIDGGRVQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTTNDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASDQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=666959 MPG41_RS03110 WP_245068378.1 649552..651336(-) (uvrC) [Helicobacter pylori strain Hpfe072]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGTTATTTTTCTGTCCGTAATAATGAAATCACGCCCA
ATCATCGTGCAAGCTTACGAATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATCTTAGAAAATTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGATGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAAGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAAGACAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTGAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGATAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATAGTGGGAACAATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTTAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTAATGCCTGAACAGATTTTACTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCTCATAAATACTCTAAAAAAATCGCTCTTAGTATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTCTTTAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGCATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTGCCAAAGAGC
CGCCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGTGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CCACACCACTAACGATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGATCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(205-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

97.138

100

0.971