Detailed information
Bioinformatically predicted
Overview
| Name | ccrB | Type | Machinery gene |
| Locus tag | SAJPND1_RS00240 | Genome accession | NZ_AP014652 |
| Coordinates | 51196..52824 (-) | Length | 542 a.a. |
| NCBI ID | WP_060871516.1 | Uniprot ID | - |
| Organism | Staphylococcus aureus strain TMUS2126 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 24482..72894 | 51196..52824 | within | 0 |
| SCCmec | 42871..59365 | 51196..52824 | within | 0 |
Gene organization within MGE regions
Location: 24482..72894
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SAJPND1_RS00100 (AXW71_RS00100) | yycF | 24940..25641 (+) | 702 | WP_000101976.1 | response regulator YycF | - |
| SAJPND1_RS00105 (AXW71_RS00105) | walK | 25654..27480 (+) | 1827 | WP_000871607.1 | cell wall metabolism sensor histidine kinase WalK | - |
| SAJPND1_RS00110 (AXW71_RS00110) | yycH | 27473..28807 (+) | 1335 | WP_001060140.1 | two-component system activity regulator YycH | - |
| SAJPND1_RS00115 (AXW71_RS00115) | yycI | 28808..29596 (+) | 789 | WP_001104168.1 | two-component system regulatory protein YycI | - |
| SAJPND1_RS00120 (AXW71_RS00120) | - | 29985..30785 (+) | 801 | WP_000088649.1 | MBL fold metallo-hydrolase | - |
| SAJPND1_RS00125 (AXW71_RS00125) | adsA | 31013..33331 (+) | 2319 | WP_000645771.1 | LPXTG-anchored adenosine synthase AdsA | - |
| SAJPND1_RS00135 (AXW71_RS00135) | rlmH | 33699..34178 (+) | 480 | WP_000704775.1 | 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH | - |
| SAJPND1_RS00140 (AXW71_RS00140) | - | 34500..35756 (+) | 1257 | WP_000566670.1 | DUF3578 domain-containing protein | - |
| SAJPND1_RS00145 (AXW71_RS00145) | - | 36171..36410 (+) | 240 | WP_001282728.1 | hypothetical protein | - |
| SAJPND1_RS00150 (AXW71_RS00150) | - | 36442..37116 (-) | 675 | WP_001106057.1 | IS6-like element IS257 family transposase | - |
| SAJPND1_RS00160 (AXW71_RS00160) | - | 37207..38190 (-) | 984 | Protein_27 | protein rep | - |
| SAJPND1_RS00170 (AXW71_RS00165) | mobV | 38436..39698 (-) | 1263 | WP_029163598.1 | MobV family relaxase | - |
| SAJPND1_RS00175 (AXW71_RS00170) | bleO | 40205..40609 (-) | 405 | WP_001242578.1 | bleomycin binding protein | - |
| SAJPND1_RS00180 (AXW71_RS00175) | aadD1 | 40826..41596 (-) | 771 | WP_001795128.1 | aminoglycoside O-nucleotidyltransferase ANT(4')-Ia | - |
| SAJPND1_RS00190 (AXW71_RS00185) | - | 42520..42825 (+) | 306 | Protein_32 | MaoC/PaaZ C-terminal domain-containing protein | - |
| SAJPND1_RS00195 (AXW71_RS00190) | mecA | 42871..44880 (-) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| SAJPND1_RS00200 (AXW71_RS00195) | - | 44977..45963 (+) | 987 | WP_001549960.1 | beta-lactam sensor/signal transducer MecR1 | - |
| SAJPND1_RS00205 (AXW71_RS00200) | - | 45935..46195 (+) | 261 | WP_001549961.1 | type I restriction enzyme endonuclease domain-containing protein | - |
| SAJPND1_RS00210 (AXW71_RS00205) | - | 46462..47661 (+) | 1200 | WP_073392450.1 | IS110-like element ISSep2 family transposase | - |
| SAJPND1_RS00215 (AXW71_RS00210) | - | 47758..49353 (-) | 1596 | Protein_37 | IS1182 family transposase | - |
| SAJPND1_RS00220 (AXW71_RS00215) | - | 49405..49911 (-) | 507 | WP_001092189.1 | DUF1643 domain-containing protein | - |
| SAJPND1_RS00225 (AXW71_RS00220) | - | 49926..50237 (-) | 312 | WP_000700851.1 | DUF960 family protein | - |
| SAJPND1_RS00235 (AXW71_RS00225) | - | 50324..50674 (-) | 351 | WP_000849672.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| SAJPND1_RS00240 (AXW71_RS00230) | ccrB | 51196..52824 (-) | 1629 | WP_060871516.1 | recombinase family protein | Machinery gene |
| SAJPND1_RS00245 (AXW71_RS00235) | ccrA | 52846..54195 (-) | 1350 | WP_002486033.1 | recombinase family protein | Machinery gene |
| SAJPND1_RS00250 (AXW71_RS00240) | - | 54429..56222 (-) | 1794 | WP_000079474.1 | DUF927 domain-containing protein | - |
| SAJPND1_RS00255 (AXW71_RS00245) | - | 56222..56518 (-) | 297 | WP_000273823.1 | single-stranded DNA-binding protein | - |
| SAJPND1_RS00260 (AXW71_RS00250) | - | 56711..57757 (-) | 1047 | WP_001042023.1 | hypothetical protein | - |
| SAJPND1_RS14055 (SAJPND1_00052) | - | 58212..58661 (+) | 450 | WP_001813878.1 | ATP-binding protein | - |
| SAJPND1_RS14060 (SAJPND1_00053) | - | 58772..59365 (+) | 594 | WP_001181652.1 | hypothetical protein | - |
| SAJPND1_RS00270 (AXW71_RS00265) | - | 59395..60195 (+) | 801 | WP_000749913.1 | abortive infection family protein | - |
| SAJPND1_RS00275 (AXW71_RS00270) | - | 60378..61313 (+) | 936 | WP_000251226.1 | dsDNA nuclease domain-containing protein | - |
| SAJPND1_RS00280 (AXW71_RS00275) | - | 61306..61914 (+) | 609 | WP_029163516.1 | hypothetical protein | - |
| SAJPND1_RS00285 (AXW71_RS00280) | - | 61911..62168 (+) | 258 | WP_020977950.1 | hypothetical protein | - |
| SAJPND1_RS00290 (AXW71_RS00285) | - | 62225..62977 (+) | 753 | WP_000417870.1 | hypothetical protein | - |
| SAJPND1_RS00295 (AXW71_RS00290) | - | 63224..64210 (-) | 987 | WP_000662022.1 | tRNA-dihydrouridine synthase | - |
| SAJPND1_RS00300 (AXW71_RS00295) | - | 64519..64722 (+) | 204 | WP_000398680.1 | DUF6007 family protein | - |
| SAJPND1_RS00305 (AXW71_RS00300) | - | 64771..65067 (+) | 297 | WP_000179888.1 | TfoX/Sxy family protein | - |
| SAJPND1_RS00310 (AXW71_RS00305) | - | 65276..65878 (+) | 603 | WP_000908959.1 | hypothetical protein | - |
| SAJPND1_RS00315 (AXW71_RS00310) | - | 66170..67084 (-) | 915 | WP_000814441.1 | alpha/beta hydrolase | - |
| SAJPND1_RS00320 (AXW71_RS00315) | - | 67263..67817 (+) | 555 | WP_020977952.1 | TetR/AcrR family transcriptional regulator C-terminal domain-containing protein | - |
| SAJPND1_RS00330 (AXW71_RS00320) | - | 68047..68784 (+) | 738 | WP_001792407.1 | methyltransferase domain-containing protein | - |
| SAJPND1_RS00335 (AXW71_RS00325) | - | 68940..69422 (+) | 483 | WP_000410569.1 | hypothetical protein | - |
| SAJPND1_RS00340 (AXW71_RS00330) | - | 69628..70614 (+) | 987 | WP_000710561.1 | phosphatidylinositol-specific phospholipase C | - |
| SAJPND1_RS00345 (AXW71_RS00335) | - | 70835..71604 (+) | 770 | Protein_62 | tandem-type lipoprotein | - |
| SAJPND1_RS00350 (AXW71_RS00340) | - | 71671..72438 (+) | 768 | WP_000649985.1 | tandem-type lipoprotein | - |
Sequence
Protein
Download Length: 542 a.a. Molecular weight: 62620.81 Da Isoelectric Point: 9.7970
>NTDB_id=66690 SAJPND1_RS00240 WP_060871516.1 51196..52824(-) (ccrB) [Staphylococcus aureus strain TMUS2126]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRMLKDAKEGNIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPDSKHELMINQHEANIVKYIFECYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKINNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKTLLDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRMLKDAKEGNIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPDSKHELMINQHEANIVKYIFECYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKINNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKTLLDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
Nucleotide
Download Length: 1629 bp
>NTDB_id=66690 SAJPND1_RS00240 WP_060871516.1 51196..52824(-) (ccrB) [Staphylococcus aureus strain TMUS2126]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTTTCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGATGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAGGTCAAAGATATATACGCTGATCGTGGTA
TTTCAGGTAAATCTATGAACAGACCTGAGCTCCAACGTATGTTGAAAGATGCAAAAGAAGGCAATATCGACTGTGTTATG
GTATACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTGTCAGAGCGTATGGAAGTCAATACTTCTTCTGGTAAACTCATGTTACAGATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAACGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTACCACTAGGTTATGACAAAATACCAGATAGTAAACACGAGCTAATGATTAACCAACATGAAGCTAATATTGTAAAATA
TATATTCGAGTGCTATGCCAAAGGACATGGCTATCGTAAAATTGCCAATGCATTGAATCACAAAGGATATGTCACTAAAA
AGGGGAAACCTTTCAGTATTAGTTCAATCACATACATCTTAGCTAACCCTTTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTGAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTTCATGGTAAAGGAACGA
ATCTGCTTACAGGCATTATCCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACAACGAATACACTTAAAGAT
GGGACCAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTAATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAAATAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGACTT
TATTGGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATTAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTATTTT
TGCCCCAAACACTATATCTTACTATTTAG
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTTTCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGATGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAGGTCAAAGATATATACGCTGATCGTGGTA
TTTCAGGTAAATCTATGAACAGACCTGAGCTCCAACGTATGTTGAAAGATGCAAAAGAAGGCAATATCGACTGTGTTATG
GTATACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTGTCAGAGCGTATGGAAGTCAATACTTCTTCTGGTAAACTCATGTTACAGATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAACGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTACCACTAGGTTATGACAAAATACCAGATAGTAAACACGAGCTAATGATTAACCAACATGAAGCTAATATTGTAAAATA
TATATTCGAGTGCTATGCCAAAGGACATGGCTATCGTAAAATTGCCAATGCATTGAATCACAAAGGATATGTCACTAAAA
AGGGGAAACCTTTCAGTATTAGTTCAATCACATACATCTTAGCTAACCCTTTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTGAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTTCATGGTAAAGGAACGA
ATCTGCTTACAGGCATTATCCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACAACGAATACACTTAAAGAT
GGGACCAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTAATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAAATAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGACTT
TATTGGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATTAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTATTTT
TGCCCCAAACACTATATCTTACTATTTAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrB | Staphylococcus aureus N315 |
98.708 |
100 |
0.987 |