Detailed information NTG0666891

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: OG782_RS17250
• Genome accession: NZ_CP108800
• Coordinates: 3937120..3939726 (-)
• Length: 868 a.a.
• NCBI ID: WP_406451913.1
• Uniprot ID: -
• Organism: Streptomyces sp. NBC_00876
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3932120..3944726

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OG782_RS17225 (OG782_17240)	-	3932331..3933629 (-)	1299	WP_406451903.1	ATP-grasp domain-containing protein	-
OG782_RS17230 (OG782_17245)	-	3933626..3934852 (-)	1227	WP_406451905.1	ATP-grasp domain-containing protein	-
OG782_RS17235 (OG782_17250)	-	3934852..3935562 (-)	711	WP_406451907.1	metallophosphoesterase	-
OG782_RS17240 (OG782_17255)	-	3935561..3936163 (+)	603	WP_406451909.1	HAD family hydrolase	-
OG782_RS17245 (OG782_17260)	-	3936409..3936969 (-)	561	WP_406451911.1	YbjN domain-containing protein	-
OG782_RS17250 (OG782_17265)	clpC	3937120..3939726 (-)	2607	WP_406451913.1	ATP-dependent chaperone ClpB	Regulator
OG782_RS17255 (OG782_17270)	-	3939922..3940326 (+)	405	WP_406451915.1	pyridoxamine 5'-phosphate oxidase family protein	-
OG782_RS17260 (OG782_17275)	-	3940424..3940744 (-)	321	WP_406451917.1	(2Fe-2S)-binding protein	-
OG782_RS17265 (OG782_17280)	-	3941080..3942048 (+)	969	WP_406451919.1	helix-turn-helix transcriptional regulator	-
OG782_RS17270 (OG782_17285)	-	3942169..3942615 (-)	447	WP_018522258.1	heat shock protein transcriptional repressor HspR	-
OG782_RS17275 (OG782_17290)	dnaJ	3942617..3943804 (-)	1188	WP_406451921.1	molecular chaperone DnaJ	-
OG782_RS17280 (OG782_17295)	grpE	3943928..3944578 (-)	651	WP_406451923.1	nucleotide exchange factor GrpE	-

Sequence

Protein

• Length: 868 a.a.
• Molecular weight: 94839.21 Da
• Isoelectric Point: 4.6876

>NTDB_id=666891 OG782_RS17250 WP_406451913.1 3937120..3939726(-) (clpC) [Streptomyces sp. NBC_00876]
MDAELTNRSRDALNAASNRAVKDGHPDLTPGHLLLALLSGEDNENIIDLLAAVEADQIAVRTETERLLGALPSVTGSTVS
PPQPNRELLAVIADAAQRAKELGDDYVSTEHLLIGTAAKGGRAGEILDGQGASAKRLLDAFEKNRGGRRVTTPDPEGQYK
ALEKFGTDFTAAAREGKLDPVIGRDQEIRRVVQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQRIVLGDVPESLKNKRLVS
LDLGAMVAGAKYRGEFEERLKTVLSEIKESDGQIITFIDELHTVVGAGAGGDSAMDAGNMLKPMLARGELRMVGATTLDE
YRERIEKDPALERRFQQVLVAEPSVEDTIAILRGLKGRYEAHHKVQIADSSLVAAATLSDRYITSRFLPDKAIDLVDEAA
SRLRMEIDSSPVEIDELQRSVDRLLMEELALKNEKDPASKQRLEKLRRDLADKQEELRGLNARWEKEKQGLNRVGELKER
LDELRGQAERAQRDGDFDTASKLLYGEIPGLERELAEADEAEQEAAGEPKETLVKEEVGPDDIADVVGAWTGIPAGRLLE
GETQKLLRMEEELGRRLIGQTEAVQAVSDAVRRTRAGIADPDRPTGSFLFLGPTGVGKTELAKALADFLFDDERAMVRID
MSEYSEKHSVARLVGAPPGYVGYEEGGQLTEAVRRRPYTVVLLDEVEKAHPEVFDILLQVLDDGRLTDGQGRTVDFRNTI
LILTSNLGSQYLVDPLTKPEEKKEQVLNVVRASFKPEFLNRLDDLVVFSALSGDELSHIAGLQIDRLAKRLADRQLALDV
TPAALAWLAEEGNDPAYGARPLRRLIQTAIGDRLAKEILAGEITDGDTVRVDRVGDGLSIGVSGARTP

Nucleotide

• Length: 2607 bp

>NTDB_id=666891 OG782_RS17250 WP_406451913.1 3937120..3939726(-) (clpC) [Streptomyces sp. NBC_00876]
GTGGACGCCGAGCTGACCAACAGGAGCCGGGACGCCCTCAACGCGGCCAGTAACAGGGCCGTGAAGGACGGGCATCCCGA
TCTGACCCCGGGGCATCTGCTGCTCGCGCTGCTCTCGGGCGAGGACAACGAGAACATCATCGACCTGCTGGCCGCCGTCG
AGGCGGACCAGATCGCCGTACGCACCGAGACCGAGCGGCTCCTGGGCGCACTGCCCAGCGTGACCGGCTCGACCGTCTCG
CCGCCGCAGCCCAACCGCGAACTGCTCGCCGTCATCGCCGACGCCGCGCAGCGGGCGAAGGAGCTCGGCGACGACTACGT
CTCCACCGAGCACCTGCTGATCGGGACCGCCGCGAAGGGCGGCCGCGCCGGTGAGATCCTCGACGGGCAGGGTGCCAGTG
CGAAGAGGCTGCTGGACGCATTCGAGAAGAACAGGGGAGGGCGCCGGGTGACGACACCGGACCCGGAGGGCCAGTACAAG
GCCCTGGAGAAATTCGGTACGGACTTCACCGCGGCCGCGCGCGAGGGCAAGCTCGACCCGGTCATCGGGCGCGACCAGGA
GATCCGCCGCGTCGTCCAGGTGCTGTCCCGCCGTACCAAGAACAACCCGGTGCTCATCGGTGAGCCCGGCGTCGGCAAGA
CGGCCGTCGTCGAAGGGCTCGCCCAGCGCATCGTCCTGGGCGACGTCCCGGAGTCCCTGAAGAACAAGCGGCTCGTCTCG
CTGGACCTGGGCGCCATGGTCGCGGGCGCGAAGTACCGCGGTGAGTTCGAGGAGCGCCTGAAGACCGTCCTCTCCGAGAT
CAAGGAGAGCGACGGCCAGATCATCACGTTCATCGACGAGCTCCACACCGTCGTGGGCGCGGGCGCCGGCGGCGACTCCG
CCATGGACGCGGGCAACATGCTCAAGCCCATGCTGGCCCGCGGCGAGCTGCGGATGGTCGGCGCCACCACGCTCGACGAG
TACCGCGAGCGGATCGAGAAGGACCCCGCCCTGGAGCGCCGCTTCCAGCAGGTGCTGGTCGCGGAGCCGTCCGTCGAGGA
CACCATCGCGATCCTGCGCGGGCTCAAGGGCCGTTACGAGGCCCACCACAAGGTGCAGATCGCGGACTCCTCGCTGGTCG
CCGCAGCCACCCTCTCCGACCGCTACATCACCTCCCGCTTCCTGCCCGACAAGGCCATCGACCTCGTCGACGAGGCGGCC
TCCCGGCTGCGCATGGAGATCGACTCCTCGCCCGTCGAGATCGACGAACTCCAGCGCTCCGTCGACCGGTTGCTCATGGA
GGAGCTGGCGCTCAAGAACGAGAAGGACCCGGCCTCCAAGCAGCGGCTGGAGAAGCTGCGCCGCGACCTCGCCGACAAGC
AGGAGGAGCTGCGCGGCCTCAACGCCCGCTGGGAGAAGGAGAAGCAGGGCCTCAACCGCGTCGGTGAGCTCAAGGAACGC
CTCGACGAGCTGCGCGGACAGGCCGAACGCGCCCAGCGCGACGGTGACTTCGACACCGCGTCCAAGCTGCTGTACGGGGA
GATCCCCGGCCTGGAGCGGGAGCTGGCCGAGGCCGACGAGGCCGAGCAGGAGGCCGCGGGCGAGCCCAAGGAGACCCTGG
TCAAGGAAGAGGTCGGACCCGACGACATCGCCGATGTCGTCGGCGCCTGGACCGGCATCCCGGCCGGACGCCTGCTGGAG
GGCGAGACCCAGAAGCTGCTGCGCATGGAGGAGGAGCTGGGCCGGCGCCTCATCGGGCAGACCGAGGCCGTGCAGGCCGT
CTCGGACGCGGTACGCCGCACCCGGGCCGGGATCGCCGACCCCGACCGGCCCACCGGATCGTTCCTCTTCCTCGGCCCCA
CCGGGGTCGGCAAGACCGAGCTGGCGAAGGCGCTCGCCGACTTCCTCTTCGACGACGAGCGGGCCATGGTCCGCATCGAC
ATGAGTGAGTACAGCGAGAAGCACAGCGTCGCCCGGCTGGTCGGTGCCCCGCCCGGGTACGTCGGCTACGAGGAGGGCGG
CCAGCTCACGGAGGCGGTCCGCCGCCGCCCGTACACCGTCGTCCTGCTGGACGAGGTGGAGAAGGCGCACCCCGAGGTCT
TCGACATCCTGCTCCAGGTCCTCGACGACGGCCGGCTCACCGACGGGCAGGGCCGGACGGTGGACTTCCGCAACACCATC
CTGATCCTGACGTCCAACCTCGGCAGCCAGTACCTGGTCGACCCGCTGACCAAGCCCGAGGAGAAGAAGGAGCAGGTCCT
GAACGTCGTGCGGGCCTCCTTCAAGCCGGAGTTCCTCAACCGGCTCGACGACCTGGTGGTCTTCTCCGCCCTGTCCGGGG
ACGAGCTCAGCCACATCGCGGGGCTCCAGATCGACCGGCTCGCCAAGCGGCTGGCCGACCGGCAGCTCGCCCTCGACGTC
ACCCCGGCCGCCCTGGCCTGGCTGGCCGAGGAGGGCAACGACCCGGCCTACGGTGCCCGGCCGCTGCGCCGCCTCATCCA
GACGGCGATCGGCGACCGGCTCGCGAAGGAGATCCTCGCGGGTGAGATCACGGACGGCGACACGGTGCGCGTGGACCGGG
TGGGCGACGGCCTGAGCATCGGCGTGAGCGGCGCCCGTACGCCGTAA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (603-764)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (771-851)

• AAA lid domain (AAA_lid_9) (344-446)

• ATPase family associated with various cellular activities (AAA) (AAA) (204-338)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (18-69)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-146)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	44.054	100	0.448
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	43.71	90.668	0.396
clpC	Lactococcus lactis subsp. cremoris KW2	46.348	82.028	0.38