Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   MPG76_RS03060 Genome accession   NZ_CP094098
Coordinates   643092..644876 (-) Length   594 a.a.
NCBI ID   WP_245039065.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe081     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 638092..649876
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG76_RS03030 (MPG76_03030) - 638679..638927 (+) 249 WP_000790557.1 RNA-binding protein -
  MPG76_RS03035 (MPG76_03035) - 639132..639953 (-) 822 WP_245039061.1 glycosyltransferase family 25 protein -
  MPG76_RS03040 (MPG76_03040) trxB 640121..641056 (-) 936 WP_021307556.1 thioredoxin-disulfide reductase -
  MPG76_RS03045 (MPG76_03045) trxA 641062..641382 (-) 321 WP_000020199.1 thioredoxin -
  MPG76_RS03050 (MPG76_03050) - 641471..641815 (-) 345 WP_154456039.1 YraN family protein -
  MPG76_RS03055 (MPG76_03055) - 641816..643081 (-) 1266 WP_245039063.1 homoserine dehydrogenase -
  MPG76_RS03060 (MPG76_03060) uvrC 643092..644876 (-) 1785 WP_245039065.1 excinuclease ABC subunit UvrC Machinery gene
  MPG76_RS03065 (MPG76_03065) - 644877..645338 (-) 462 WP_245039067.1 hypothetical protein -
  MPG76_RS03070 (MPG76_03070) - 645330..645509 (+) 180 WP_000468796.1 hypothetical protein -
  MPG76_RS03075 (MPG76_03075) - 645521..646162 (-) 642 WP_245039069.1 ATP-binding cassette domain-containing protein -
  MPG76_RS03080 (MPG76_03080) - 646166..647827 (-) 1662 WP_245039071.1 ABC transporter permease/substrate-binding protein -
  MPG76_RS03085 (MPG76_03085) - 648007..648444 (-) 438 WP_001031792.1 hypothetical protein -
  MPG76_RS03090 (MPG76_03090) motB 648448..649215 (-) 768 WP_060760624.1 flagellar motor protein MotB -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68816.98 Da        Isoelectric Point: 9.5754

>NTDB_id=666819 MPG76_RS03060 WP_245039065.1 643092..644876(-) (uvrC) [Helicobacter pylori strain Hpfe081]
MADLLSSLKNLSHNSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSVHNNEITPNHRASLHIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGSHKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQDFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEAQSLFKLECMPYRVEIFDT
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYTQMSELLTRRALDFNKEPPPNLWVIDGGRAQLNIALEILKNSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTANDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=666819 MPG76_RS03060 WP_245039065.1 643092..644876(-) (uvrC) [Helicobacter pylori strain Hpfe081]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTCATAACAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCTGTCCACAATAATGAAATCACGCCCA
ATCATCGCGCAAGCTTACACATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTAGAAAACGAACAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTATATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAAGATATTTTAGACAGCTTGTATGAATTGCTCCCATTAGTTCAAAAGAAA
AATTGCATCAAAGACAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGTCTTTCTAATAACTTGCGTTTTGAAGAAGCTCTCATTTATAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCCTTTACTTGTATGGATTTGGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATAGTGGGAGCCATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTTAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTAATGCCAGAACAAATCTTATTGAAC
GCTTGCTCTAATGAAACACTTAAAGAATTGCAAGATTTTATCTCTCACCAATACTCTAAAAAAATCGCTCTTAGTATTCC
TAAAAAAGGCGATAAACTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCAATCGCTTTTTAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAACGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTAATAAAGAGC
CACCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAACAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CCACACCGCTAACGATACTTTTAAATTACTCCCTAGCGACAAGCGCTTGCAATGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCGCTTTTAAAAGAAAAGGGTATA
GGAGAAGCTAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAACAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrB/uvrC motif (UVR)

(205-239)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(384-538)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.296

100

0.963